Role of gender in explaining metabolic syndrome risk factors in an Iranian rural population using structural equation modelling.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
25 09 2023
Historique:
received: 07 02 2023
accepted: 10 08 2023
medline: 27 9 2023
pubmed: 26 9 2023
entrez: 25 9 2023
Statut: epublish

Résumé

Many factors can lead to an increase in the prevalence of metabolic syndrome (MetS) in different populations. Using an advanced structural equation model (SEM), this study is aimed to determine the most important risk factors of MetS, as a continuous latent variable, using a large number of males and females. We also aimed to evaluate the interrelations among the associated factors involved in the development of MetS. This study used data derived from the Fasa PERSIAN cohort study, a branch of the PERSIAN cohort study, for participants aged 35 to 70 years with 10,138 males and females. SEM was used to evaluate the direct and indirect effects, as well as gender effects of influencing factors. Results from the SEM showed that in females most changes in MetS are described by waist circumference (WC), followed by hypertension (HP) and triglyceride (TG), while in males most changes in MetS are described by WC, followed by TG then fasting blood glucose (FBG). Results from the SEM confirmed the gender effects of social status on MetS, mediated by sleep and controlled by age, BMI, ethnicity and physical activity. This study also shows that the integration of TG and WC within genders could be useful as a screening criterion for MetS in our study population.

Identifiants

pubmed: 37749166
doi: 10.1038/s41598-023-40485-y
pii: 10.1038/s41598-023-40485-y
pmc: PMC10520016
doi:

Substances chimiques

Triglycerides 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

16007

Informations de copyright

© 2023. Springer Nature Limited.

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Auteurs

Marjan Nouri-Keshtkar (M)

Department of Developmental Biology, University of Science and Culture, Tehran, Iran.
Department of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran.

Mohadeseh Shojaei Shahrokhabadi (M)

Biostatistics Research Group, Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.

Azadeh Ghaheri (A)

Department of Basic and Population Based Studies in NCD, Reproductive Epidemiology Research Center, Royan Institute, ACECR, Tehran, Iran.

Roya Hosseini (R)

Department of Basic and Population Based Studies in NCD, Reproductive Epidemiology Research Center, Royan Institute, ACECR, Tehran, Iran.
Department of Andrology, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran.

Hassan Ketabi (H)

Mobile Telecommunication Company of Iran, Tehran, Iran.

Mojtaba Farjam (M)

Noncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran.

Ding-Geng Chen (DG)

College of Health Solutions, Arizona State University, Phoenix, AZ, USA.
Department of statistics, University of Pretoria, Pretoria, South Africa.

Mehdi Rezaeian (M)

Noncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran.

Reza Homayounfar (R)

Noncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran. r_homayounfar@yahoo.com.
National Nutrition and Food Technology Research Institute, Faculty of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran. r_homayounfar@yahoo.com.

Yaser Tahamtani (Y)

Department of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran. y.tahamtani@royan-rc.ac.ir.
Department of Basic and Population Based Studies in NCD, Reproductive Epidemiology Research Center, Royan Institute, ACECR, Tehran, Iran. y.tahamtani@royan-rc.ac.ir.

Mehdi Totonchi (M)

Department of Genetics, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran. totonchimehdi@gmail.com.

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