Characteristics of Children and Adolescents with Hyperinsulinemia Undergoing Oral Glucose Tolerance Test: A Single-Center Retrospective Observational Study.

diabetes mellitus glycemic dysregulation hyperinsulinism insulin resistance metabolic syndrome obesity oral glucose tolerance test pediatric endocrinology personalized medicine

Journal

Diseases (Basel, Switzerland)
ISSN: 2079-9721
Titre abrégé: Diseases
Pays: Switzerland
ID NLM: 101636232

Informations de publication

Date de publication:
28 Aug 2023
Historique:
received: 31 07 2023
revised: 22 08 2023
accepted: 25 08 2023
medline: 27 9 2023
pubmed: 27 9 2023
entrez: 27 9 2023
Statut: epublish

Résumé

The aim of this study was to evaluate a potential correlation between results of the oral glucose tolerance test (OGTT) and the auxological/metabolic parameters in a cohort of overweight patients assessed for suspicion of hyperinsulinism. We analyzed 206 patients, comparing those with insulin peak below (nonhyperinsulinemic) and over 100 uIU/mL (hyperinsulinemic) at the OGTT. We found a significant difference in weight (

Identifiants

pubmed: 37754306
pii: diseases11030110
doi: 10.3390/diseases11030110
pmc: PMC10530243
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Clelia Cipolla (C)

Department of Life Sciences and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo Francesco Vito n. 1, 00168 Rome, Italy.

Ilaria Lazzareschi (I)

Department of Life Sciences and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo Francesco Vito n. 1, 00168 Rome, Italy.
Università Cattolica Sacro Cuore, 00168 Rome, Italy.

Antonietta Curatola (A)

Department of Life Sciences and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo Francesco Vito n. 1, 00168 Rome, Italy.

Claudia Lasorella (C)

Department of Life Sciences and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo Francesco Vito n. 1, 00168 Rome, Italy.

Lucia Celeste Pane (LC)

Department of Life Sciences and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo Francesco Vito n. 1, 00168 Rome, Italy.

Linda Sessa (L)

Department of Life Sciences and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo Francesco Vito n. 1, 00168 Rome, Italy.

Giulia Rotunno (G)

Department of Life Sciences and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo Francesco Vito n. 1, 00168 Rome, Italy.

Donato Rigante (D)

Department of Life Sciences and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo Francesco Vito n. 1, 00168 Rome, Italy.
Università Cattolica Sacro Cuore, 00168 Rome, Italy.

Giorgio Sodero (G)

Department of Life Sciences and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo Francesco Vito n. 1, 00168 Rome, Italy.

Classifications MeSH