Extracellular Vesicles and Their Impact on the Biology of Protozoan Parasites.

extracellular vesicles immune response intercellular communication protozoa

Journal

Tropical medicine and infectious disease
ISSN: 2414-6366
Titre abrégé: Trop Med Infect Dis
Pays: Switzerland
ID NLM: 101709042

Informations de publication

Date de publication:
15 Sep 2023
Historique:
received: 07 08 2023
revised: 11 09 2023
accepted: 11 09 2023
medline: 27 9 2023
pubmed: 27 9 2023
entrez: 27 9 2023
Statut: epublish

Résumé

Extracellular vesicles (EVs) are lipid-membrane-bound structures produced naturally by all cells and have a variety of functions. EVs act as vehicles for transporting important molecular signals from one cell to another. Several parasites have been shown to secrete EVs, and their biological functions have been extensively studied. EVs have been shown to facilitate communication with the host cells (such as modulation of the host's immune system or promoting attachment and invasion into the host cells) or for communication between parasitic cells (e.g., transferring drug-resistance genes or factors modulating stage conversion). It is clear that EVs play an important role in host-parasite interactions. In this review, we summarized the latest research on the EVs secreted by protozoan parasites and their role in host-parasite and parasite-parasite communications.

Identifiants

pubmed: 37755909
pii: tropicalmed8090448
doi: 10.3390/tropicalmed8090448
pmc: PMC10537256
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

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Auteurs

Manu Sharma (M)

Division of Infectious Diseases, School of Medicine, Stanford University, Stanford, CA 94305, USA.

Daniela Lozano-Amado (D)

Division of Infectious Diseases, School of Medicine, Stanford University, Stanford, CA 94305, USA.

Debabrata Chowdhury (D)

Division of Infectious Diseases, School of Medicine, Stanford University, Stanford, CA 94305, USA.

Upinder Singh (U)

Division of Infectious Diseases, School of Medicine, Stanford University, Stanford, CA 94305, USA.
Department of Microbiology and Immunology, School of Medicine, Stanford University, Stanford, CA 94305, USA.

Classifications MeSH