Verbal Learning Impairment in Parkinson's Disease: Role of the Frontostriatal System in Working and Strategic Memory.
Parkinson’s disease
Strategic memory
Verbal learning
Journal
Neuro-degenerative diseases
ISSN: 1660-2862
Titre abrégé: Neurodegener Dis
Pays: Switzerland
ID NLM: 101189034
Informations de publication
Date de publication:
2023
2023
Historique:
received:
15
03
2023
accepted:
21
09
2023
medline:
7
12
2023
pubmed:
28
9
2023
entrez:
27
9
2023
Statut:
ppublish
Résumé
Learning is a long-term memory process, influenced by working memory control processes, including recognition of semantic properties of items by which subjects generate a semantic structure of engrams. The aim of the study was to investigate the verbal learning strategies of individuals with Parkinson's disease (PD). Thirty individuals with idiopathic PD and healthy control (HC) subjects were tested with a multi-trial word list learning, under two conditions: without cue and then with an explicit cue suggesting the categories in the list, respectively. In comparison to HC subjects, individuals with PD recalled fewer words and achieved a reduced number of categorical clusters; the strategical cue did not improve their performance. This suggests, besides a difficulty in identifying the correct learning strategy, a deficit in working memory, which undermines the strategy implementation.
Identifiants
pubmed: 37757782
pii: 000534307
doi: 10.1159/000534307
doi:
Types de publication
News
Langues
eng
Sous-ensembles de citation
IM
Pagination
20-24Informations de copyright
© 2023 S. Karger AG, Basel.