Neighborhood Deprivation and Neural Tube Defects.
Journal
Epidemiology (Cambridge, Mass.)
ISSN: 1531-5487
Titre abrégé: Epidemiology
Pays: United States
ID NLM: 9009644
Informations de publication
Date de publication:
01 11 2023
01 11 2023
Historique:
medline:
29
9
2023
pubmed:
28
9
2023
entrez:
27
9
2023
Statut:
ppublish
Résumé
Individual measures of socioeconomic status (SES) have been associated with an increased risk of neural tube defects (NTDs); however, the association between neighborhood SES and NTD risk is unknown. Using data from the National Birth Defects Prevention Study (NBDPS) from 1997 to 2011, we investigated the association between measures of census tract SES and NTD risk. The study population included 10,028 controls and 1829 NTD cases. We linked maternal addresses to census tract SES measures and used these measures to calculate the neighborhood deprivation index. We used generalized estimating equations to calculate adjusted odds ratios (aORs) and 95% confidence intervals (CIs) estimating the impact of quartiles of census tract deprivation on NTDs adjusting for maternal race-ethnicity, maternal education, and maternal age at delivery. Quartiles of higher neighborhood deprivation were associated with NTDs when compared with the least deprived quartile (Q2: aOR = 1.2; 95% CI = 1.0, 1.4; Q3: aOR = 1.3, 95% CI = 1.1, 1.5; Q4 (highest): aOR = 1.2; 95% CI = 1.0, 1.4). Results for spina bifida were similar; however, estimates for anencephaly and encephalocele were attenuated. Associations differed by maternal race-ethnicity. Our findings suggest that residing in a census tract with more socioeconomic deprivation is associated with an increased risk for NTDs, specifically spina bifida.
Sections du résumé
BACKGROUND
Individual measures of socioeconomic status (SES) have been associated with an increased risk of neural tube defects (NTDs); however, the association between neighborhood SES and NTD risk is unknown. Using data from the National Birth Defects Prevention Study (NBDPS) from 1997 to 2011, we investigated the association between measures of census tract SES and NTD risk.
METHODS
The study population included 10,028 controls and 1829 NTD cases. We linked maternal addresses to census tract SES measures and used these measures to calculate the neighborhood deprivation index. We used generalized estimating equations to calculate adjusted odds ratios (aORs) and 95% confidence intervals (CIs) estimating the impact of quartiles of census tract deprivation on NTDs adjusting for maternal race-ethnicity, maternal education, and maternal age at delivery.
RESULTS
Quartiles of higher neighborhood deprivation were associated with NTDs when compared with the least deprived quartile (Q2: aOR = 1.2; 95% CI = 1.0, 1.4; Q3: aOR = 1.3, 95% CI = 1.1, 1.5; Q4 (highest): aOR = 1.2; 95% CI = 1.0, 1.4). Results for spina bifida were similar; however, estimates for anencephaly and encephalocele were attenuated. Associations differed by maternal race-ethnicity.
CONCLUSIONS
Our findings suggest that residing in a census tract with more socioeconomic deprivation is associated with an increased risk for NTDs, specifically spina bifida.
Identifiants
pubmed: 37757869
doi: 10.1097/EDE.0000000000001655
pii: 00001648-202311000-00002
doi:
Types de publication
Journal Article
Research Support, U.S. Gov't, P.H.S.
Langues
eng
Sous-ensembles de citation
IM
Pagination
774-785Informations de copyright
Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.
Déclaration de conflit d'intérêts
The authors report no conflicts of interest.
Références
Avagliano L, Massa V, George TM, Qureshy S, Bulfamante GP, Finnell RH. Overview on neural tube defects: from development to physical characteristics. Birth Defects Res. 2019;111:1455–1467.
Williams J, Mai CT, Mulinare J, et al.; Centers for Disease Control and Prevention. Updated estimates of neural tube defects prevented by mandatory folic acid fortification - United States, 1995-2011. MMWR Morb Mortal Wkly Rep. 2015;64:1–5.
Blencowe H, Kancherla V, Moorthie S, Darlison MW, Modell B. Estimates of global and regional prevalence of neural tube defects for 2015: a systematic analysis. Ann N Y Acad Sci. 2018;1414:31–46.
Canfield MA, Mai CT, Wang Y, et al.; National Birth Defects Prevention Network. The association between race/ethnicity and major birth defects in the United States, 1999-2007. Am J Public Health. 2014;104:e14–e23.
Frey L, Hauser WA. Epidemiology of neural tube defects. Epilepsia. 2003;44:4–13.
Copp AJ, Stanier P, Greene ND. Neural tube defects: recent advances, unsolved questions, and controversies. Lancet Neurol. 2013;12:799–810.
Endalifer ML, Diress G. Epidemiology and determinant factors of neural tube defect: narrative review. Surg Neurol Int. 2020;11:81.
Kim J, Langlois PH, Mitchell LE, Agopian AJ. Maternal occupation and the risk of neural tube defects in offspring. Arch Environ Occup Health. 2018;73:304–312.
Bibbins-Domingo K, Grossman DC, Curry SJ, et al.; US Preventive Services Task Force. Folic acid supplementation for the prevention of neural tube defects: US preventive services task force recommendation statement. JAMA. 2017;317:183–189.
Murphy ME, Westmark CJ. Folic acid fortification and neural tube defect risk: analysis of the food fortification initiative dataset. Nutrients. 2020;12:247.
Agha MM, Glazier RH, Moineddin R, Moore AM, Guttmann A. Food fortification and decline in the prevalence of neural tube defects: does public intervention reduce the socioeconomic gap in prevalence?. Int J Environ Res Public Health. 2013;10:1312–1323.
Grewal J, Carmichael SL, Song J, Shaw GM. Neural tube defects: an analysis of neighbourhood- and individual-level socio-economic characteristics. Paediatr Perinat Epidemiol. 2009;23:116–124.
Olesen C, Thrane N, Rønholt AM, Olsen J, Henriksen TB. Association between social position and congenital anomalies: a population-based study among 19,874 Danish women. Scand J Public Health. 2009;37:246–251.
Rosano A, Del Bufalo E, Burgio A. [Socioeconomic status and risk of congenital malformations]. Epidemiol Prev. 2008;32:21–26.
Diez Roux AV, Mair C. Neighborhoods and health. Ann N Y Acad Sci. 2010;1186:125–145.
Wasserman CR, Shaw GM, Selvin S, Gould JB, Syme SL. Socioeconomic status, neighborhood social conditions, and neural tube defects. Am J Public Health. 1998;88:1674–1680.
Vrijheid M, Dolk H, Stone D, Abramsky L, Alberman E, Scott JE. Socioeconomic inequalities in risk of congenital anomaly. Arch Dis Child. 2000;82:349–352.
Messer LC, Laraia BA, Kaufman JS, et al. The development of a standardized neighborhood deprivation index. J Urban Health. 2006;83:1041–1062.
Ekeke P, Mendez DD, Yanowitz TD, Catov JM. Racial differences in the biochemical effects of stress in pregnancy. Int J Environ Res Public Health. 2020;17:6941.
Elo IT, Culhane JF, Kohler IV, et al. Neighbourhood deprivation and small-for-gestational-age term births in the United States. Paediatr Perinat Epidemiol. 2009;23:87–96.
Janevic T, Stein CR, Savitz DA, Kaufman JS, Mason SM, Herring AH. Neighborhood deprivation and adverse birth outcomes among diverse ethnic groups. Ann Epidemiol. 2010;20:445–451.
Reefhuis J, Gilboa SM, Anderka M, et al.; National Birth Defects Prevention Study. The national birth defects prevention study: a review of the methods. Birth Defects Res A Clin Mol Teratol. 2015;103:656–669.
Rasmussen SA, Olney RS, Holmes LB, Lin AE, Keppler-Noreuil KM, Moore CA; National Birth Defects Prevention Study. Guidelines for case classification for the national birth defects prevention study. Birth Defects Res A Clin Mol Teratol. 2003;67:193–201.
McGuinn LA, Windham GC, Messer LC, et al. Air pollution, neighborhood deprivation, and autism spectrum disorder in the study to explore early development. Environ Epidemiol. 2019;3:e067.
O’Campo P, Burke JG, Culhane J, et al. Neighborhood deprivation and preterm birth among non-Hispanic black and white women in eight geographic areas in the United States. Am J Epidemiol. 2007;167:155–163.
Textor J, van der Zander B, Gilthorpe MS, Liskiewicz M, Ellison GT. Robust causal inference using directed acyclic graphs: the R package “dagitty.”. Int J Epidemiol. 2016;45:1887–1894.
Wasserstein RL, Lazar NA. The ASA statement on p-values: context, process, and purpose. The Am Stat. 2016;70:129–133.
Williams LJ, Mai CT, Edmonds LD, et al. Prevalence of spina bifida and anencephaly during the transition to mandatory folic acid fortification in the United States. Teratology. 2002;66:33–39.
Centers for Disease Control and Prevention. Spina bifida and anencephaly before and after folic acid mandate--United States, 1995-1996 and 1999-2000. MMWR Morb Mortal Wkly Rep. 2004;53:362–365.
Ren A. Chapter 61 - Environmental pollutants and neural tube defects. In: Gupta RC, ed. Reproductive and Developmental Toxicology (Third Edition). Academic Press; 2022:1221–1243.
Padula AM, Yang W, Carmichael SL, et al. Air pollution, neighborhood acculturation factors, and neural tube defects among Hispanic women in California. Birth Defects Res. 2017;109:403–422.
Padula AM, Yang W, Carmichael SL, et al. Air Pollution, neighbourhood socioeconomic factors, and neural tube defects in the San Joaquin valley of California. Paediatr Perinat Epidemiol. 2015;29:536–545.
van der Pal-de Bruin KM, de Walle HE, de Rover CM, et al. Influence of educational level on determinants of folic acid use. Paediatr Perinat Epidemiol. 2003;17:256–263.
Wang M, Wang ZP, Gong R, Zhao ZT. Maternal smoking during pregnancy and neural tube defects in offspring: a meta-analysis. Childs Nerv Syst. 2014;30:83–89.
Grewal J, Carmichael SL, Ma C, Lammer EJ, Shaw GM. Maternal periconceptional smoking and alcohol consumption and risk for select congenital anomalies. Birth Defects Res A Clin Mol Teratol. 2008;82:519–526.
Carmichael SL, Ma C, Tinker S, Rasmussen SA, Shaw GM; National Birth Defects Prevention Study. Maternal stressors and social support as risks for delivering babies with structural birth defects. Paediatr Perinat Epidemiol. 2014;28:338–344.
Adkins-Jackson PB, Chantarat T, Bailey ZD, Ponce NA. Measuring structural racism: a guide for epidemiologists and other health researchers. Am J Epidemiol. 2022;191:539–547.
Kothari CL, Paul R, Dormitorio B, et al. The interplay of race, socioeconomic status and neighborhood residence upon birth outcomes in a high black infant mortality community. SSM Popul Health. 2016;2:859–867.
Mukhtar A, Kramer MR, Oakley GP Jr, Kancherla V. Race and ethnicity and preconception folic acid supplement use among pregnant women in Georgia, PRAMS 2009 to 2011. Birth Defects Res. 2017;109:38–48.
Marchetta CM, Hamner HC. Blood folate concentrations among women of childbearing age by race/ethnicity and acculturation, NHANES 2001-2010. Matern Child Nutr. 2016;12:39–50.
Chacko MR, Anding R, Kozinetz CA, Grover JL, Smith PB. Neural tube defects: knowledge and preconceptional prevention practices in minority young women. Pediatrics. 2003;112:536–542.
Assari S. Unequal gain of equal resources across racial groups. Int J Health Policy Manag. 2018;7:1–9.
Dunlop AL, Essalmi AG, Alvalos L, et al.; Program Collaborators for Environmental Influences on Child Health Outcomes. Racial and geographic variation in effects of maternal education and neighborhood-level measures of socioeconomic status on gestational age at birth: findings from the ECHO cohorts. PLoS One. 2021;16:e0245064.
Markides KS, Eschbach K. Aging, migration, and mortality: current status of research on the Hispanic paradox. J Gerontol B Psychol Sci Soc Sci. 2005;60 Spec No 2:68–75.
American Community Survey Information Guide 2017; Census.gov.
Canfield MA, Ramadhani TA, Langlois PH, Waller DK. Residential mobility patterns and exposure misclassification in epidemiologic studies of birth defects. J Expo Sci Environ Epidemiol. 2006;16:538–543.