Binding interaction of environmental DNA with typical emerging perfluoroalkyl acids and its impact on bioavailability.

DNA, Environmental Biological Availability Acids DNA Fluorocarbons / analysis Water Pollutants, Chemical / analysis Alkanesulfonic Acids / analysis Environmental Monitoring / methods
Bioavailability DNA Density functional theory Emerging PFAAs Isothermal titration calorimetry (ITC)

Journal

The Science of the total environment
ISSN: 1879-1026
Titre abrégé: Sci Total Environ
Pays: Netherlands
ID NLM: 0330500

Informations de publication

Date de publication:
01 Jan 2024
Historique:
received: 08 03 2023
revised: 17 08 2023
accepted: 24 09 2023
medline: 15 11 2023
pubmed: 28 9 2023
entrez: 27 9 2023
Statut: ppublish

Résumé

As the replacement compounds of perfluoroalkyl acids (PFAAs), emerging PFAAs generally exhibit equal or more hazardous toxicity than legacy PFAAs. Numerous DNA as environmental organic matters coexists with emerging PFAAs, but their interactions and the resulting interaction impacts on the bioavailability of emerging PFAAs remain insufficiently understood. Here, we studied the binding strength and mechanism between DNA and emerging PFAAs (perfluorobutyric acid, perfluorobutylsulfonic acid, and hexafluoropropylene oxide dimer acid) using perfluorooctanoic acid as the control, and further investigated the impacts of DNA binding on the bioavailability of the emerging PFAAs. Isothermal titration calorimetry and quantum chemical calculation found that the emerging PFAAs could bind with DNA bases (main thymine) by van der Waals force and halogen-bond, showing the binding affinities in the range of 7.87 × 10

Identifiants

DOI: 10.1016/j.scitotenv.2023.167392 PMID: 37758138
pubmed: 37758138
pii: S0048-9697(23)06019-9
doi: 10.1016/j.scitotenv.2023.167392
pii:
doi:

Substances chimiques

DNA, Environmental 0
Acids 0
DNA 9007-49-2
Fluorocarbons 0
Water Pollutants, Chemical 0
Alkanesulfonic Acids 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

167392

Informations de copyright

Copyright © 2023 Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Chao Qin (C)

Guangdong Provincial Research Center for Environment Pollution Control and Remediation Materials, College of Life Science and Technology, Jinan University, Guangzhou 510632, China; Institute of Organic Contaminant Control and Soil Remediation, College of Resources and Environmental Sciences, Nanjing Agricultural University, Nanjing 210095, China.

Lei Xiang (L)

Guangdong Provincial Research Center for Environment Pollution Control and Remediation Materials, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.

Yi-Ze Wang (YZ)

Guangdong Provincial Research Center for Environment Pollution Control and Remediation Materials, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.

Peng-Fei Yu (PF)

Guangdong Provincial Research Center for Environment Pollution Control and Remediation Materials, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.

Can Meng (C)

Guangdong Provincial Research Center for Environment Pollution Control and Remediation Materials, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.

Yan-Wen Li (YW)

Guangdong Provincial Research Center for Environment Pollution Control and Remediation Materials, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.

Hai-Ming Zhao (HM)

Guangdong Provincial Research Center for Environment Pollution Control and Remediation Materials, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.

Xiaojie Hu (X)

Institute of Organic Contaminant Control and Soil Remediation, College of Resources and Environmental Sciences, Nanjing Agricultural University, Nanjing 210095, China.

Yanzheng Gao (Y)

Institute of Organic Contaminant Control and Soil Remediation, College of Resources and Environmental Sciences, Nanjing Agricultural University, Nanjing 210095, China.

Ce-Hui Mo (CH)

Guangdong Provincial Research Center for Environment Pollution Control and Remediation Materials, College of Life Science and Technology, Jinan University, Guangzhou 510632, China. Electronic address: tchmo@jnu.edu.cn.

Articles similaires

Environmental impact assessment of Flora and its role in offsetting carbon along National Highway-16, India.

H Ramamohan, S Raminaidu, I Sudhakara Rao et al.
1.00
India Carbon Sequestration Environmental Monitoring Carbon Biomass

The critical need for long-term biomonitoring: The case study of a major river system in Anatolia.

Irmak Kurtul
1.00
Rivers Turkey Biodiversity Environmental Monitoring Animals

Modeling NPP and NDVI time series in different bioclimatic regions of Iran.

Fahimeh Sayedzadeh, Saied Soltani, Reza Modarres
1.00
Iran Environmental Monitoring Seasons Ecosystem Forests

Beneath the surface: assessing pollution levels near major solid waste dumpsites in Lagos, Nigeria.

Udeme Olaniyan, May A Massoud, Ibrahim Alameddine et al.
1.00
Nigeria Environmental Monitoring Solid Waste Waste Disposal Facilities Refuse Disposal

Classifications MeSH

questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ADN › ADN environnemental › Binding interaction of environmental DNA with...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Pharmacocinétique › Biodisponibilité › Binding interaction of environmental DNA with...
questionsmedicales.fr › Produits chimiques inorganiques › Acides › Binding interaction of environmental DNA with...
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ADN › Binding interaction of environmental DNA with...
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Hydrocarbures halogénés › Hydrocarbures fluorés › Fluorocarbones › Binding interaction of environmental DNA with...
questionsmedicales.fr › Actions chimiques et utilisations › Actions toxiques › Polluants environnementaux › Polluants de l'eau › Polluants chimiques de l'eau › Binding interaction of environmental DNA with...
questionsmedicales.fr › Composés chimiques organiques › Composés du soufre › Acides du soufre › Acides sulfoniques › Acides alcanesulfoniques › Binding interaction of environmental DNA with...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Pratiques en santé publique › Surveillance de l'environnement › Binding interaction of environmental DNA with...