Indomethacin Induces Spermidine/Spermine-N
cancer
indomethacin
non-steroidal anti-inflammatory drugs
polyamines
Journal
Biomolecules
ISSN: 2218-273X
Titre abrégé: Biomolecules
Pays: Switzerland
ID NLM: 101596414
Informations de publication
Date de publication:
12 09 2023
12 09 2023
Historique:
received:
04
07
2023
revised:
30
08
2023
accepted:
31
08
2023
medline:
4
10
2023
pubmed:
28
9
2023
entrez:
28
9
2023
Statut:
epublish
Résumé
Indomethacin is a non-selective NSAID used against pain and inflammation. Although cyclooxygenase (COX) inhibition is considered indomethacin's primary action mechanism, COX-independent ways are associated with beneficial effects in cancer. In colon cancer cells, the activation of the peroxisome proliferator-activated receptor-γ (PPAR-γ) is related to the increase in spermidine/spermine-N
Identifiants
pubmed: 37759783
pii: biom13091383
doi: 10.3390/biom13091383
pmc: PMC10526249
pii:
doi:
Substances chimiques
Acetyltransferases
EC 2.3.1.-
Antineoplastic Agents
0
CDC2 Protein Kinase
EC 2.7.11.22
CDK1 protein, human
EC 2.7.11.22
Cyclooxygenase 2
EC 1.14.99.1
Indomethacin
XXE1CET956
methoctramine
NVJ76B897D
Oxidoreductases
EC 1.-
Peroxisome Proliferator-Activated Receptors
0
diamine N-acetyltransferase
EC 2.3.1.57
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Références
Mol Biol Rep. 2014 Jan;41(1):145-54
pubmed: 24190492
Mol Cell Biol. 2012 Apr;32(8):1453-67
pubmed: 22354986
Adv Exp Med Biol. 2020;1274:29-54
pubmed: 32894506
Cancer Chemother Pharmacol. 2006 Sep;58(3):348-53
pubmed: 16331495
Nat Rev Cancer. 2018 Nov;18(11):681-695
pubmed: 30181570
Commun Integr Biol. 2011 May;4(3):267-75
pubmed: 21980556
Nat Chem Biol. 2006 Sep;2(9):458-66
pubmed: 16921358
Biochem Pharmacol. 2001 Dec 15;62(12):1587-95
pubmed: 11755111
Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):2169-74
pubmed: 23345430
Mol Med Rep. 2012 Apr;5(4):1037-42
pubmed: 22294330
J Radiat Res. 2019 May 1;60(3):281-288
pubmed: 30839063
Lung Cancer. 2012 Aug;77(2):246-51
pubmed: 22480996
Cancer Manag Res. 2018 Oct 15;10:4631-4640
pubmed: 30410398
J Lipid Res. 2013 Nov;54(11):3116-29
pubmed: 23943857
BMC Mol Biol. 2007 Aug 10;8:66
pubmed: 17692122
Biochem J. 2006 Feb 15;394(Pt 1):317-24
pubmed: 16262603
Cells. 2021 Jun 13;10(6):
pubmed: 34199169
Cancer Causes Control. 2011 Dec;22(12):1709-20
pubmed: 21987079
Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7859-64
pubmed: 12810952
Expert Rev Mol Med. 2013 Feb 22;15:e3
pubmed: 23432971
Oncol Rep. 2012 Jan;27(1):94-100
pubmed: 21956494
Exp Cell Res. 1996 Jan 10;222(1):179-88
pubmed: 8549662
Int J Oncol. 2017 Dec;51(6):1661-1673
pubmed: 29075787
Exp Cell Res. 1993 Sep;208(1):48-53
pubmed: 7689479
Br J Cancer. 2008 Jan 15;98(1):232-7
pubmed: 18087276
RNA Biol. 2018 Feb 1;15(2):251-260
pubmed: 29168431
Int J Cancer. 2002 Apr 20;98(6):817-23
pubmed: 11948457
Int J Mol Sci. 2022 Jan 27;23(3):
pubmed: 35163356
J Biol Chem. 1991 Apr 25;266(12):7754-8
pubmed: 2019600
Am J Physiol Endocrinol Metab. 2008 Jun;294(6):E995-1010
pubmed: 18349109
J Biol Chem. 2011 Dec 23;286(51):43816-43829
pubmed: 21998300
Cancer Sci. 2019 Oct;110(10):3018-3026
pubmed: 31361372
Eur J Clin Invest. 2001 Oct;31(10):887-93
pubmed: 11737227
Cancer Res. 1991 Aug 1;51(15):4090-6
pubmed: 1855224
Cancer Lett. 2021 Oct 28;519:91-104
pubmed: 34186159
Int J Nanomedicine. 2017 Aug 22;12:6153-6168
pubmed: 28883726
Leukemia. 2018 Mar;32(3):663-674
pubmed: 28690315
Oncogene. 1992 Jan;7(1):171-80
pubmed: 1311061
Mol Cell Biol. 1990 Jul;10(7):3607-18
pubmed: 2192260
Iran J Basic Med Sci. 2020 Dec;23(12):1544-1550
pubmed: 33489027
Eurasian J Med. 2018 Jun;50(2):116-121
pubmed: 30002579
Pharmacol Rep. 2020 Oct;72(5):1152-1160
pubmed: 32710395
Curr Oncol Rep. 2021 Nov 8;23(12):146
pubmed: 34748112
J Cell Physiol. 2018 Feb;233(2):1685-1699
pubmed: 28681929
Pharmacol Res Perspect. 2015 Jun;3(3):e00149
pubmed: 26171228
Nat Commun. 2020 Jan 7;11(1):52
pubmed: 31911608
FASEB J. 2001 Oct;15(12):2057-72
pubmed: 11641233
Oncol Rep. 2019 Jan;41(1):590-598
pubmed: 30320343
J Enzyme Inhib Med Chem. 2019 Dec;34(1):740-752
pubmed: 30829081
Biomed Chromatogr. 2014 Apr;28(4):492-9
pubmed: 24122856
J Biol Chem. 2003 Nov 28;278(48):47762-75
pubmed: 14506281
Amino Acids. 2004 Jun;26(3):217-33
pubmed: 15221502
Sci Rep. 2017 May 12;7(1):1875
pubmed: 28500305
Bioinformatics. 2016 Sep 15;32(18):2866-8
pubmed: 27153664
Front Pharmacol. 2020 Feb 28;10:1670
pubmed: 32256343