How Did COVID-19 Impact the Antimicrobial Consumption and Bacterial Resistance Profiles in Brazil?
SARS-CoV-2
antimicrobial resistance
healthcare-related infections (HAIs)
Journal
Antibiotics (Basel, Switzerland)
ISSN: 2079-6382
Titre abrégé: Antibiotics (Basel)
Pays: Switzerland
ID NLM: 101637404
Informations de publication
Date de publication:
28 Aug 2023
28 Aug 2023
Historique:
received:
02
08
2023
revised:
19
08
2023
accepted:
21
08
2023
medline:
28
9
2023
pubmed:
28
9
2023
entrez:
28
9
2023
Statut:
epublish
Résumé
The indiscriminate use of antibiotics has favored the selective pressure of multidrug resistance among microorganisms. This research evaluated the pattern of antibiotic prescriptions among the Brazilian population between January 2018 and December 2021. Additionally, the study sought to analyze the incidence rates of central line-associated bloodstream infection (CLABSI) and examine the profiles of antibiotic resistance. We assessed the hospital and community antimicrobial consumption from the National Health Surveillance Agency Database and correlated it to microorganisms. The consumption of antimicrobials in the hospital environment increased by 26% in 2021, highlighting polymyxin B, which increased by 204%. In 2021, 244,266 cases of CLABSI were reported, indicating a nosocomial infection rate of 7.9%. The rate of resistance to polymyxin B was higher in
Identifiants
pubmed: 37760671
pii: antibiotics12091374
doi: 10.3390/antibiotics12091374
pmc: PMC10526034
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
ID : 401727/2020-3; 307946/2022-3
Organisme : Fundação de Apoio ao Desenvolvimento do Ensino, Ciência e Tecnologia do Estado de Mato Grosso do Sul (FUNDECT)
ID : 325/2022;113/2023;76/2023
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