Exploring the Synthetic Chemistry of Phenyl-3-(5-aryl-2-furyl)- 2-propen-1-ones as Urease Inhibitors: Mechanistic Approach through Urease Inhibition, Molecular Docking and Structure-Activity Relationship.
Claisen–Schmidt condensation
SAR
furan carbaldehyde
furan chalcones
molecular docking
urease inhibition
Journal
Biomedicines
ISSN: 2227-9059
Titre abrégé: Biomedicines
Pays: Switzerland
ID NLM: 101691304
Informations de publication
Date de publication:
30 Aug 2023
30 Aug 2023
Historique:
received:
02
08
2023
revised:
22
08
2023
accepted:
25
08
2023
medline:
28
9
2023
pubmed:
28
9
2023
entrez:
28
9
2023
Statut:
epublish
Résumé
Furan chalcone scaffolds belong to the most privileged and promising oxygen-containing heterocyclic class of compounds, which have a wide spectrum of therapeutic applications in the field of pharmaceutics, pharmacology, and medicinal chemistry. This research described the synthesis of a series of twelve novel and seven reported furan chalcone (conventional synthetic approach) analogues
Identifiants
pubmed: 37760869
pii: biomedicines11092428
doi: 10.3390/biomedicines11092428
pmc: PMC10525509
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : The Researchers Supporting Project Number (RSP2023R457), King Saud University, Riyadh, Saudi Arabia.
ID : Researchers Supporting Project Number (RSP2023R457)
Références
Microbiol Rev. 1989 Mar;53(1):85-108
pubmed: 2651866
Farmaco. 2000 Apr;55(4):256-63
pubmed: 10966156
Drug Des Devel Ther. 2021 Jul 29;15:3289-3312
pubmed: 34354342
Sci Rep. 2017 Mar 03;7:42717
pubmed: 28256516
Pharmaceuticals (Basel). 2022 Oct 11;15(10):
pubmed: 36297362
J Biol Chem. 1992 Oct 5;267(28):20024-7
pubmed: 1400317
Farmaco. 2001 Dec;56(12):919-27
pubmed: 11829111
Eur J Med Chem. 2019 Mar 1;165:133-141
pubmed: 30665143
Nucleic Acids Res. 2021 Jul 2;49(W1):W5-W14
pubmed: 33893803
Sci Rep. 2020 May 22;10(1):8503
pubmed: 32444844
Sci Rep. 2023 Jun 22;13(1):10136
pubmed: 37349372
Chem Rev. 2017 Jun 28;117(12):7762-7810
pubmed: 28488435
Molecules. 2022 Feb 02;27(3):
pubmed: 35164286
J Inorg Biochem. 2008 Oct;102(10):1846-53
pubmed: 18728000
Prog Mol Biol Transl Sci. 2020;174:307-330
pubmed: 32828469
Int J Mol Sci. 2022 Sep 19;23(18):
pubmed: 36142889
Nat Struct Biol. 2001 Jun;8(6):505-9
pubmed: 11373617
Arch Pharm (Weinheim). 2013 Jun;346(6):423-46
pubmed: 23712847
J Enzyme Inhib Med Chem. 2020 Dec;35(1):404-413
pubmed: 31880473
Antimicrob Agents Chemother. 2002 Aug;46(8):2613-8
pubmed: 12121941
Bioorg Chem. 2020 Jan;94:103359
pubmed: 31640931
Eur J Med Chem. 2010 Nov;45(11):5200-7
pubmed: 20828889
Daru. 2022 Jun;30(1):29-37
pubmed: 35040104
Nat Rev Mol Cell Biol. 2001 Jun;2(6):457-66
pubmed: 11389469
J Comput Chem. 2010 Jan 30;31(2):455-61
pubmed: 19499576
Mini Rev Med Chem. 2018;18(2):113-141
pubmed: 27488585
Mini Rev Med Chem. 2022;22(9):1268-1280
pubmed: 34983345
Sci Rep. 2023 Jan 2;13(1):21
pubmed: 36593349
J Enzyme Inhib Med Chem. 2009 Feb;24(1):151-6
pubmed: 18608771
J Adv Res. 2018 Jan 31;13:101-112
pubmed: 30094085
PLoS One. 2022 Dec 15;17(12):e0278027
pubmed: 36520942
Pharmaceuticals (Basel). 2023 Feb 23;16(3):
pubmed: 36986444
J Enzyme Inhib Med Chem. 2009 Apr;24(2):437-46
pubmed: 18629680
Bioorg Chem. 2020 Jan;95:103479
pubmed: 31901517
Chem Commun (Camb). 2003 May 21;(10):1109-13
pubmed: 12778695
Pharmaceuticals (Basel). 2023 Jun 01;16(6):
pubmed: 37375776
Molecules. 2004 Mar 31;9(4):241-55
pubmed: 18007428
Int J Mol Sci. 2023 Feb 03;24(3):
pubmed: 36769327
Mol Microbiol. 1993 Sep;9(5):907-13
pubmed: 7934918