The Utility of NGS Analysis in Homologous Recombination Deficiency Tracking.

DNA repair biomarkers homologous recombination deficiency loss of heterozygosity poly (ADP-ribose) polymerase (PARP) inhibitors precision oncology

Journal

Diagnostics (Basel, Switzerland)
ISSN: 2075-4418
Titre abrégé: Diagnostics (Basel)
Pays: Switzerland
ID NLM: 101658402

Informations de publication

Date de publication:
15 Sep 2023
Historique:
received: 11 08 2023
revised: 05 09 2023
accepted: 07 09 2023
medline: 28 9 2023
pubmed: 28 9 2023
entrez: 28 9 2023
Statut: epublish

Résumé

Several tumor types have been efficiently treated with PARP inhibitors (PARPis), which are now approved for the treatment of ovarian, breast, prostate, and pancreatic cancers. The

Identifiants

pubmed: 37761329
pii: diagnostics13182962
doi: 10.3390/diagnostics13182962
pmc: PMC10529941
pii:
doi:

Types de publication

Journal Article

Langues

eng

Références

Onco Targets Ther. 2022 Feb 24;15:165-180
pubmed: 35237050
Nat Commun. 2021 May 3;12(1):2487
pubmed: 33941784
Br J Cancer. 2012 Nov 6;107(10):1776-82
pubmed: 23047548
JCO Precis Oncol. 2022 Jun;6:e2100531
pubmed: 35772050
JCO Precis Oncol. 2017 Nov;1:1-13
pubmed: 35172494
Clin Cancer Res. 2022 Apr 1;28(7):1412-1421
pubmed: 34740923
Bioinformatics. 2021 Jul 27;37(13):1909-1911
pubmed: 32449758
Breast Cancer Res Treat. 2019 Apr;174(3):627-637
pubmed: 30607631
Cancer Res Treat. 2020 Oct;52(4):1135-1144
pubmed: 32340084
Front Oncol. 2020 Apr 28;10:570
pubmed: 32457830
Nat Commun. 2020 Nov 4;11(1):5584
pubmed: 33149131
NPJ Breast Cancer. 2019 Aug 8;5:23
pubmed: 31428676
Science. 2017 Mar 17;355(6330):1152-1158
pubmed: 28302823
Lancet. 2017 Oct 28;390(10106):1949-1961
pubmed: 28916367
Proc Natl Acad Sci U S A. 2010 Sep 28;107(39):16910-5
pubmed: 20837533
J Transl Med. 2021 Sep 8;19(1):385
pubmed: 34496866
Cancer Discov. 2021 Nov;11(11):2812-2827
pubmed: 34045297
J Genet Couns. 2018 Feb;27(1):131-139
pubmed: 28780754
Cancers (Basel). 2022 Jun 15;14(12):
pubmed: 35740616
Per Med. 2014 Mar;11(2):197-210
pubmed: 29751382
Oncologist. 2022 Mar 11;27(3):167-174
pubmed: 35274707
Biomark Res. 2019 Nov 15;7:25
pubmed: 31807308
Transl Oncol. 2020 Feb;13(2):410-422
pubmed: 31901781
J Clin Oncol. 2020 Dec 20;38(36):4274-4282
pubmed: 33119476
Cancer Discov. 2015 Nov;5(11):1137-54
pubmed: 26463832
ESMO Open. 2021 Jun;6(3):100144
pubmed: 34015643
Cancers (Basel). 2021 Feb 24;13(5):
pubmed: 33668244
N Engl J Med. 2020 May 28;382(22):2091-2102
pubmed: 32343890
Mod Pathol. 2021 Jun;34(6):1185-1193
pubmed: 33462368
Int J Mol Sci. 2017 Jan 04;18(1):
pubmed: 28054957
Cancers (Basel). 2022 Aug 27;14(17):
pubmed: 36077694
Recent Pat Anticancer Drug Discov. 2018;13(4):392-410
pubmed: 29512470
Nature. 2022 Oct;610(7931):343-348
pubmed: 36071165

Auteurs

Aikaterini Tsantikidi (A)

Genekor Medical S.A., 15344 Athens, Greece.

Eirini Papadopoulou (E)

Genekor Medical S.A., 15344 Athens, Greece.

Vasiliki Metaxa-Mariatou (V)

Genekor Medical S.A., 15344 Athens, Greece.

George Kapetsis (G)

Genekor Medical S.A., 15344 Athens, Greece.

Georgios Tsaousis (G)

Genekor Medical S.A., 15344 Athens, Greece.

Angeliki Meintani (A)

Genekor Medical S.A., 15344 Athens, Greece.

Chrysiida Florou-Chatzigiannidou (C)

Genekor Medical S.A., 15344 Athens, Greece.

Maria Gazouli (M)

Department of Basic Medical Sciences, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.

Christos Papadimitriou (C)

Second Department of Surgery, Aretaieion Hospital, Medical School, National and Kapodistrian University of Athens, 11528 Athens, Greece.

Eleni Timotheadou (E)

Department of Medical Oncology, Papageorgiou Hospital, School of Medicine, Aristotle University of Thessaloniki, 56429 Thessaloniki, Greece.

Athanasios Kotsakis (A)

Oncology Department, University General Hospital of Larissa, 41334 Larissa, Greece.

Anastasios Boutis (A)

First Department of Clinical Oncology, Theagenio Hospital, 54639 Thessaloniki, Greece.

Ioannis Boukovinas (I)

Oncology Department, Bioclinic of Thessaloniki, 54622 Thessaloniki, Greece.

Eleftherios Kampletsas (E)

Department of Medical, Oncology, University Hospital of Ioannina, 45500 Ioannina, Greece.

Loukas Kontovinis (L)

Oncology Department, "Euromedica" General Clinic, 54645 Thessaloniki, Greece.

Elena Fountzilas (E)

Second Department of Medical Oncology, Euromedica General Clinic, 54645 Thessaloniki, Greece.

Charalampos Andreadis (C)

Second Department of Clinical Oncology, Theagenio Hospital, 54639 Thessaloniki, Greece.

Charisios Karanikiotis (C)

Department of Medical Oncology, 424 Army General Hospital, 56429 Thessaloniki, Greece.

Dimitrios Filippou (D)

Department of Anatomy, Faculty of Health Sciences, Medical School, National and Kapodistrian University of Athens, 15772 Athens, Greece.

Georgios Theodoropoulos (G)

Department of Surgery, National and Kapodistrian University of Athens, Hippocration General Hospital, 15772 Athens, Greece.

Mustafa Özdoğan (M)

Division of Medical Oncology, Memorial Hospital, Antalya 07025, Turkey.

George Nasioulas (G)

Second Department of Medical Oncology, Euromedica General Clinic, 54645 Thessaloniki, Greece.

Classifications MeSH