Characteristics and Drug Utilization of Patients with Hereditary Angioedema in Italy, a Real-World Analysis.
HAE
administrative databases
danazol
long-term prophylaxis
Journal
Healthcare (Basel, Switzerland)
ISSN: 2227-9032
Titre abrégé: Healthcare (Basel)
Pays: Switzerland
ID NLM: 101666525
Informations de publication
Date de publication:
10 Sep 2023
10 Sep 2023
Historique:
received:
12
06
2023
revised:
24
07
2023
accepted:
06
09
2023
medline:
28
9
2023
pubmed:
28
9
2023
entrez:
28
9
2023
Statut:
epublish
Résumé
This real-world analysis investigated the characteristics and treatment patterns of patients with hereditary angioedema (HAE) in Italy using the administrative data of health units across Italy. Patients were identified via exemption code or HAE-specific treatments (thus, all known forms, type I, II and, III, were included). The index date was that of first prescription of HAE treatments within the inclusion period (01/2010-06/2021) or of the date of exemption. The number of HAE patients included was 148 (43.2% male, mean age 43.3 years). Gastrointestinal disorders affected 36.5% patients, hypertension affected 28.4%, hypercholesterolemia affected 11.5%, and depression affected 9.5%. The frequent gastrointestinal involvement was further confirmed by the use of antiemetics and systemic antihistamines that doubled after the index date. Among patients enrolled by treatment (
Identifiants
pubmed: 37761706
pii: healthcare11182509
doi: 10.3390/healthcare11182509
pmc: PMC10530529
pii:
doi:
Types de publication
Journal Article
Langues
eng
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