High Tumor-Infiltrating Lymphocyte Count Is Associated with Distinct Gene Expression Profile and Longer Patient Survival in Advanced Ovarian Cancer.

CD4-positive T-lymphocytes CD45-positive leukocytes CD8-positive T-lymphocytes NanoString immunohistochemistry leukocyte common antigens ovarian neoplasms

Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
05 Sep 2023
Historique:
received: 31 07 2023
revised: 26 08 2023
accepted: 03 09 2023
medline: 28 9 2023
pubmed: 28 9 2023
entrez: 28 9 2023
Statut: epublish

Résumé

Cancer-related immunity plays a significant role in the outcome of ovarian cancer, but the exact mechanisms are not fully explored. A retrospective, real-life observational study was conducted including 57 advanced ovarian cancer patients. Immunohistochemistry for CD4

Identifiants

pubmed: 37761986
pii: ijms241813684
doi: 10.3390/ijms241813684
pmc: PMC10530512
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : National Research and Innovation Fund
ID : NVKP_16-1-2016-0004
Organisme : Semmelweis University
ID : APC coverage

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Auteurs

Andras Jozsef Barna (AJ)

Department of Obstetrics and Gynecology, Saint Pantaleon Hospital, H-2400 Dunaujvaros, Hungary.
Division of Oncology, Department of Internal Medicine and Oncology, Semmelweis University, H-1083 Budapest, Hungary.

Zoltan Herold (Z)

Division of Oncology, Department of Internal Medicine and Oncology, Semmelweis University, H-1083 Budapest, Hungary.

Miklos Acs (M)

Department of Surgery, University Hospital, D-93053 Regensburg, Germany.

Sandor Bazsa (S)

Department of Obstetrics and Gynecology, Saint Pantaleon Hospital, H-2400 Dunaujvaros, Hungary.

Jozsef Gajdacsi (J)

Directorate General of Medical Quality Assurance, Semmelweis University, H-1085 Budapest, Hungary.

Tamas Marton Garay (TM)

Division of Oncology, Department of Internal Medicine and Oncology, Semmelweis University, H-1083 Budapest, Hungary.
Faculty of Information Technology and Bionics, Pazmany Peter Catholic University, H-1083 Budapest, Hungary.

Magdolna Herold (M)

Division of Oncology, Department of Internal Medicine and Oncology, Semmelweis University, H-1083 Budapest, Hungary.
Department of Internal Medicine and Hematology, Semmelweis University, H-1088 Budapest, Hungary.

Lilla Madaras (L)

Department of Pathology, Forensic and Insurance Medicine, Semmelweis University, H-1091 Budapest, Hungary.

Dorottya Muhl (D)

Division of Oncology, Department of Internal Medicine and Oncology, Semmelweis University, H-1083 Budapest, Hungary.

Akos Nagy (A)

Department of Pathology and Experimental Cancer Research, Semmelweis University, H-1085 Budapest, Hungary.

Attila Marcell Szasz (AM)

Division of Oncology, Department of Internal Medicine and Oncology, Semmelweis University, H-1083 Budapest, Hungary.

Magdolna Dank (M)

Division of Oncology, Department of Internal Medicine and Oncology, Semmelweis University, H-1083 Budapest, Hungary.

Classifications MeSH