Serum Levels of S100B Protein and Myelin Basic Protein as a Potential Biomarkers of Recurrent Depressive Disorders.
S100B protein
depressive disorders
depressive episode
glial fibrillar acid protein
myelin basic protein
proteins of nerve tissue damage
recurrent depressive disorder
Journal
Journal of personalized medicine
ISSN: 2075-4426
Titre abrégé: J Pers Med
Pays: Switzerland
ID NLM: 101602269
Informations de publication
Date de publication:
21 Sep 2023
21 Sep 2023
Historique:
received:
15
08
2023
revised:
13
09
2023
accepted:
19
09
2023
medline:
28
9
2023
pubmed:
28
9
2023
entrez:
28
9
2023
Statut:
epublish
Résumé
Nowadays, nervous tissue damage proteins in serum are considered promising drug targets and biomarkers of Mood Disorders. In a cross-sectional naturalistic study, the S100B, MBP and GFAP levels in the blood serum were compared between two diagnostic groups (patients with Depressive Episode (DE, n = 28) and patients with Recurrent Depressive Disorder (RDD, n = 21)), and healthy controls (n = 25). The diagnostic value of serum markers was assessed by ROC analysis. In the DE group, we did not find changed levels of S100B, MBP and GFAP compared with controls. In the RDD group, we found decreased S100B level (
Identifiants
pubmed: 37763190
pii: jpm13091423
doi: 10.3390/jpm13091423
pmc: PMC10532562
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : The Russian Science Foundation
ID : 22-15-00084
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