Chitosan-Based Self-Healing Hydrogel: From Fabrication to Biomedical Application.
chitosan
customized drug delivery
fabrication
hydrogel
self-healing
smart biosensors
three/four dimensional (3D/4D) printing
tissue engineering
Journal
Polymers
ISSN: 2073-4360
Titre abrégé: Polymers (Basel)
Pays: Switzerland
ID NLM: 101545357
Informations de publication
Date de publication:
14 Sep 2023
14 Sep 2023
Historique:
received:
26
07
2023
revised:
04
09
2023
accepted:
11
09
2023
medline:
28
9
2023
pubmed:
28
9
2023
entrez:
28
9
2023
Statut:
epublish
Résumé
Biocompatible self-healing hydrogels are new-generation smart soft materials that hold great promise in biomedical fields. Chitosan-based self-healing hydrogels, mainly prepared via dynamic imine bonds, have attracted broad attention due to their mild preparation conditions, excellent biocompatibility, and self-recovery ability under a physiological environment. In this review, we present a comprehensive overview of the design and fabrication of chitosan-based self-healing hydrogels, and summarize their biomedical applications in tissue regeneration, customized drug delivery, smart biosensors, and three/four dimensional (3D/4D) printing. Finally, we will discuss the challenges and future perspectives for the development of chitosan-based self-healing hydrogels in the biomedical field.
Identifiants
pubmed: 37765622
pii: polym15183768
doi: 10.3390/polym15183768
pmc: PMC10535505
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
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