Mannose-Binding Lectins as Potent Antivirals against SARS-CoV-2.
COVID-19
SARS-CoV-2
antivirals
glycans
mannose-biding lectins
natural compounds
Journal
Viruses
ISSN: 1999-4915
Titre abrégé: Viruses
Pays: Switzerland
ID NLM: 101509722
Informations de publication
Date de publication:
06 09 2023
06 09 2023
Historique:
received:
23
05
2023
revised:
17
08
2023
accepted:
30
08
2023
medline:
29
9
2023
pubmed:
28
9
2023
entrez:
28
9
2023
Statut:
epublish
Résumé
The SARS-CoV-2 entry into host cells is mainly mediated by the interactions between the viral spike protein (S) and the ACE-2 cell receptor, which are highly glycosylated. Therefore, carbohydrate binding agents may represent potential candidates to abrogate virus infection. Here, we evaluated the in vitro anti-SARS-CoV-2 activity of two mannose-binding lectins isolated from the Brazilian plants
Identifiants
pubmed: 37766292
pii: v15091886
doi: 10.3390/v15091886
pmc: PMC10536204
pii:
doi:
Substances chimiques
Antiviral Agents
0
Mannose-Binding Lectins
0
Lectins
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
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