Comparison of the efficacy of altrenogest versus transdermal progestin patches on estrus synchronization and ovulation in mares.
altrenogest
estrus synchronization
mare
progestin
transdermal patch
Journal
Veterinary world
ISSN: 0972-8988
Titre abrégé: Vet World
Pays: India
ID NLM: 101504872
Informations de publication
Date de publication:
Aug 2023
Aug 2023
Historique:
received:
21
04
2023
accepted:
18
07
2023
medline:
28
9
2023
pubmed:
28
9
2023
entrez:
28
9
2023
Statut:
ppublish
Résumé
The adhesive progestin patch was investigated for estrus synchronization in mares because this method is convenient and safe in other species. This study aimed to compare the efficacy of a transdermal progestin patch versus oral altrenogest on estrus synchronization, preovulatory follicle development, and ovulation. Twenty-four broodmares were randomly divided into two groups. In Group 1, mares (n = 12) were fed 0.044 mg/kg altrenogest daily for 14 days. Group 2 (n = 12) mares were treated with adhesive transdermal progestin patches for 14 days. Mares were observed for estrus daily, from day 3 until day 7, after hormone withdrawal. Follicular development was determined by ultrasonography. The preovulatory follicle size and ovulation time after hormone treatments and ovulation rate were determined for both groups. Plasma progesterone levels were measured during the experimental periods and 2 days after hormone termination in both groups. The results revealed that the transdermal progestin patch efficiently controlled follicular growth and estrus synchronization in mares. The percentage of mares exhibiting estrus was similar in the altrenogest (100.00%) and transdermal patch (91.67%) groups. Ovulation rates were equivalent with either altrenogest or progestin patch protocols (91.67% [11/12] vs. 83.33% [10/12]). In addition, the preovulatory follicle size was similar in mares treated with altrenogest and progestin patches. This study revealed that the transdermal progestin patch provides effective estrus synchronization and ovulation, similar to altrenogest treatment. However, the transdermal patch was more convenient with a shorter predictable ovulation time after estrus synchronization and should be considered as an alternative method for mares.
Sections du résumé
Background and Aim
UNASSIGNED
The adhesive progestin patch was investigated for estrus synchronization in mares because this method is convenient and safe in other species. This study aimed to compare the efficacy of a transdermal progestin patch versus oral altrenogest on estrus synchronization, preovulatory follicle development, and ovulation.
Materials and Methods
UNASSIGNED
Twenty-four broodmares were randomly divided into two groups. In Group 1, mares (n = 12) were fed 0.044 mg/kg altrenogest daily for 14 days. Group 2 (n = 12) mares were treated with adhesive transdermal progestin patches for 14 days. Mares were observed for estrus daily, from day 3 until day 7, after hormone withdrawal. Follicular development was determined by ultrasonography. The preovulatory follicle size and ovulation time after hormone treatments and ovulation rate were determined for both groups. Plasma progesterone levels were measured during the experimental periods and 2 days after hormone termination in both groups.
Results
UNASSIGNED
The results revealed that the transdermal progestin patch efficiently controlled follicular growth and estrus synchronization in mares. The percentage of mares exhibiting estrus was similar in the altrenogest (100.00%) and transdermal patch (91.67%) groups. Ovulation rates were equivalent with either altrenogest or progestin patch protocols (91.67% [11/12] vs. 83.33% [10/12]). In addition, the preovulatory follicle size was similar in mares treated with altrenogest and progestin patches.
Conclusion
UNASSIGNED
This study revealed that the transdermal progestin patch provides effective estrus synchronization and ovulation, similar to altrenogest treatment. However, the transdermal patch was more convenient with a shorter predictable ovulation time after estrus synchronization and should be considered as an alternative method for mares.
Identifiants
pubmed: 37766710
doi: 10.14202/vetworld.2023.1667-1672
pii: Vetworld-16-1667
pmc: PMC10521185
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1667-1672Informations de copyright
Copyright: © Kajaysri and Wutthiwitthayaphong.
Déclaration de conflit d'intérêts
The authors declare that they have no competing interests.
Références
Theriogenology. 1988 Jul;30(1):181-93
pubmed: 16726461
Am J Obstet Gynecol. 2004 Apr;190(4 Suppl):S49-53
pubmed: 15105798
Equine Vet J. 1983 Oct;15(4):371-2
pubmed: 6641685
Theriogenology. 2017 Sep 15;100:66-71
pubmed: 28708535
Vet J. 2005 Jan;169(1):113-5
pubmed: 15683772
J Anim Sci. 1983 Apr;56(4):901-10
pubmed: 6406416
Theriogenology. 2007 Nov;68(8):1183-91
pubmed: 17904213
Vet World. 2020 Oct;13(10):2039-2045
pubmed: 33281335
J Equine Vet Sci. 2019 Jan;72:41-46
pubmed: 30929782
Theriogenology. 1992 Dec;38(6):1091-106
pubmed: 16727207
Vet Clin North Am Small Anim Pract. 2022 May;52(3):631-657
pubmed: 35465903
Theriogenology. 2009 Aug;72(3):417-24
pubmed: 19476990
Theriogenology. 1981 Aug;16(2):231-7
pubmed: 16725636
Vet J. 2013 Aug;197(2):324-8
pubmed: 23384437