Case Report: Tracheal infiltration with wheezing revealing Hodgkin's disease.

Hodgkin’s disease chemotherapy trachea wheezing

Journal

F1000Research
ISSN: 2046-1402
Titre abrégé: F1000Res
Pays: England
ID NLM: 101594320

Informations de publication

Date de publication:
2023
Historique:
accepted: 07 09 2023
medline: 28 9 2023
pubmed: 28 9 2023
entrez: 28 9 2023
Statut: epublish

Résumé

Hodgkin's disease with an initial tracheobronchial involvement is not common. The symptoms might be misleading, resulting in a diagnosis delay. We report the case of a 38-year-old woman with a one-month history of wheezing associated with a dry cough. The physical examination revealed a good general state of health, bilateral wheezing and supra-clavicular lymphadenopathy. The adenopathy biopsy's histopathology revealed Hodgkin lymphoma. The whole body FDG-PET scan was an important tool to assess the diagnosis as well as for the staging. The patient was treated with chemotherapy. Another unusual aspect is the tracheobronchial metastasis confirmed by a bronchial biopsy. Thus, our patient was put on a second-line chemotherapy. She died one year after the initial diagnosis. To conclude, it is an atypical clinical presentation of an Hodgkin lymphoma with a tracheobronchial relapse. It should be considered in the differential diagnosis of asthma or a tracheal tumor.

Identifiants

pubmed: 37767019
doi: 10.12688/f1000research.130928.2
pmc: PMC10521064
doi:

Types de publication

Case Reports

Langues

eng

Sous-ensembles de citation

IM

Pagination

404

Informations de copyright

Copyright: © 2023 Daboussi S et al.

Déclaration de conflit d'intérêts

No competing interests were disclosed.

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Auteurs

Selsabil Daboussi (S)

University of Tunis El Manar, Tunis, Tunisia.
Pneumology Department, Military Hospital of Tunis, Tunisia, 1008, Tunisia.

Asma Saidane (A)

Pneumology Department, Military Hospital of Tunis, Tunisia, 1008, Tunisia.

Samira Mhamdi (S)

University of Tunis El Manar, Tunis, Tunisia.
Pneumology Department, Military Hospital of Tunis, Tunisia, 1008, Tunisia.

Nouha Boubaker (N)

Pneumology Department, Military Hospital of Tunis, Tunisia, 1008, Tunisia.

Chaabane Mariem (C)

Pneumology Department, Military Hospital of Tunis, Tunisia, 1008, Tunisia.

Chiraz Aichaouia (C)

University of Tunis El Manar, Tunis, Tunisia.
Pneumology Department, Military Hospital of Tunis, Tunisia, 1008, Tunisia.

Ghedira Hela (G)

University of Tunis El Manar, Tunis, Tunisia.
Hematology Department, Military hospital of Tunis,, Tunis, 10008, Tunisia.

Fehmi Msadek (F)

University of Tunis El Manar, Tunis, Tunisia.
Hematology Department, Military hospital of Tunis,, Tunis, 10008, Tunisia.

Moetemri Zied (M)

University of Tunis El Manar, Tunis, Tunisia.
Pneumology Department, Military Hospital of Tunis, Tunisia, 1008, Tunisia.

Classifications MeSH