Endogenous Regeneration of Alveolar Bone by Decellularized Tooth Matrix.

alveolar bone defect decellularized extracellular matrix decellularized tooth matrix endogenous bone regeneration

Journal

Bulletin of experimental biology and medicine
ISSN: 1573-8221
Titre abrégé: Bull Exp Biol Med
Pays: United States
ID NLM: 0372557

Informations de publication

Date de publication:
Aug 2023
Historique:
received: 22 11 2022
pubmed: 28 9 2023
medline: 28 9 2023
entrez: 28 9 2023
Statut: ppublish

Résumé

The efficiency of bone tissue regeneration by decellularized tooth matrix, demineralized tooth matrix, and commercial xenograft Bio-Oss Spongiosa was compared on the model of a critical-size circular defect in the alveolar bone of the upper jaw of adult Wistar rats. The defect healing dynamics was assessed using histological, histomorphometrical, and immunohistochemical methods on days 30 and 60. In contrast to demineralized matrix and commercial xenograft, decellularized matrix induces the formation of the new bone tissue by day 60. Decellularized matrix can be considered as a biomaterial for cell-free tissue engineering for alveolar bone restoration in dentistry and maxillofacial surgery.

Identifiants

pubmed: 37768453
doi: 10.1007/s10517-023-05908-w
pii: 10.1007/s10517-023-05908-w
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

592-599

Informations de copyright

© 2023. Springer Science+Business Media, LLC, part of Springer Nature.

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Auteurs

A V Latyshev (AV)

A. I. Yevdokimov Moscow State University of Medicine and Dentistry c caйтa, Ministry of Health of the Russian Federation, Moscow, Russia.

T I Danilova (TI)

A. I. Yevdokimov Moscow State University of Medicine and Dentistry c caйтa, Ministry of Health of the Russian Federation, Moscow, Russia.

A V Kuznetsova (AV)

A. I. Yevdokimov Moscow State University of Medicine and Dentistry c caйтa, Ministry of Health of the Russian Federation, Moscow, Russia.
N. K. Koltsov Institute of Developmental Biology, Russian Academy of Sciences, Moscow, Russia.

O P Popova (OP)

A. I. Yevdokimov Moscow State University of Medicine and Dentistry c caйтa, Ministry of Health of the Russian Federation, Moscow, Russia.

N N Butorina (NN)

N. K. Koltsov Institute of Developmental Biology, Russian Academy of Sciences, Moscow, Russia.

A Yu Drobyshev (AY)

A. I. Yevdokimov Moscow State University of Medicine and Dentistry c caйтa, Ministry of Health of the Russian Federation, Moscow, Russia.

A A Ivanov (AA)

A. I. Yevdokimov Moscow State University of Medicine and Dentistry c caйтa, Ministry of Health of the Russian Federation, Moscow, Russia. butivanov@yandex.ru.

Classifications MeSH