Endogenous Regeneration of Alveolar Bone by Decellularized Tooth Matrix.
alveolar bone defect
decellularized extracellular matrix
decellularized tooth matrix
endogenous bone regeneration
Journal
Bulletin of experimental biology and medicine
ISSN: 1573-8221
Titre abrégé: Bull Exp Biol Med
Pays: United States
ID NLM: 0372557
Informations de publication
Date de publication:
Aug 2023
Aug 2023
Historique:
received:
22
11
2022
pubmed:
28
9
2023
medline:
28
9
2023
entrez:
28
9
2023
Statut:
ppublish
Résumé
The efficiency of bone tissue regeneration by decellularized tooth matrix, demineralized tooth matrix, and commercial xenograft Bio-Oss Spongiosa was compared on the model of a critical-size circular defect in the alveolar bone of the upper jaw of adult Wistar rats. The defect healing dynamics was assessed using histological, histomorphometrical, and immunohistochemical methods on days 30 and 60. In contrast to demineralized matrix and commercial xenograft, decellularized matrix induces the formation of the new bone tissue by day 60. Decellularized matrix can be considered as a biomaterial for cell-free tissue engineering for alveolar bone restoration in dentistry and maxillofacial surgery.
Identifiants
pubmed: 37768453
doi: 10.1007/s10517-023-05908-w
pii: 10.1007/s10517-023-05908-w
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
592-599Informations de copyright
© 2023. Springer Science+Business Media, LLC, part of Springer Nature.
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