Physical activity and exercise for the prevention and management of mild cognitive impairment and dementia: a collaborative international guideline.
Cognition
Dementia
Exercise
Guidelines
Mild cognitive impairment
Older adult
Physical activity
Journal
European geriatric medicine
ISSN: 1878-7649
Titre abrégé: Eur Geriatr Med
Pays: Switzerland
ID NLM: 101533694
Informations de publication
Date de publication:
Oct 2023
Oct 2023
Historique:
received:
01
08
2023
accepted:
28
08
2023
pubmed:
28
9
2023
medline:
28
9
2023
entrez:
28
9
2023
Statut:
ppublish
Résumé
Physical activity and exercise have been suggested as effective interventions for the prevention and management of mild cognitive impairment (MCI) and dementia, but there are no international guidelines. To create a set of evidence- and expert consensus-based prevention and management recommendations regarding physical activity (any bodily movement produced by skeletal muscles that results in energy expenditure) and exercise (a subset of physical activity that is planned, structured, repetitive), applicable to a range of individuals from healthy older adults to those with MCI/dementia. Guideline content was developed with input from several scientific and lay representatives' societies. A systematic search across multidisciplinary databases was carried out until October 2021. Recommendations for prevention and management were developed according to the GRADE and complemented by consensus statements from the expert panels. Physical activity may be considered for the primary prevention of dementia. In people with MCI there is continued uncertainty about the role of physical activity in slowing the conversion to dementia. Mind-body interventions have the greatest supporting evidence. In people with moderate dementia, exercise may be used for maintaining disability and cognition. All these recommendations were based on a very low/low certainty of evidence. Although the scientific evidence on the beneficial role of physical activity and exercise in preserving cognitive functions in subjects with normal cognition, MCI or dementia is inconclusive, this panel, composed of scientific societies and other stakeholders, recommends their implementation based on their beneficial effects on almost all facets of health.
Sections du résumé
BACKGROUND
BACKGROUND
Physical activity and exercise have been suggested as effective interventions for the prevention and management of mild cognitive impairment (MCI) and dementia, but there are no international guidelines.
OBJECTIVES
OBJECTIVE
To create a set of evidence- and expert consensus-based prevention and management recommendations regarding physical activity (any bodily movement produced by skeletal muscles that results in energy expenditure) and exercise (a subset of physical activity that is planned, structured, repetitive), applicable to a range of individuals from healthy older adults to those with MCI/dementia.
METHODS
METHODS
Guideline content was developed with input from several scientific and lay representatives' societies. A systematic search across multidisciplinary databases was carried out until October 2021. Recommendations for prevention and management were developed according to the GRADE and complemented by consensus statements from the expert panels.
RECOMMENDATIONS
CONCLUSIONS
Physical activity may be considered for the primary prevention of dementia. In people with MCI there is continued uncertainty about the role of physical activity in slowing the conversion to dementia. Mind-body interventions have the greatest supporting evidence. In people with moderate dementia, exercise may be used for maintaining disability and cognition. All these recommendations were based on a very low/low certainty of evidence.
CONCLUSIONS
CONCLUSIONS
Although the scientific evidence on the beneficial role of physical activity and exercise in preserving cognitive functions in subjects with normal cognition, MCI or dementia is inconclusive, this panel, composed of scientific societies and other stakeholders, recommends their implementation based on their beneficial effects on almost all facets of health.
Identifiants
pubmed: 37768499
doi: 10.1007/s41999-023-00858-y
pii: 10.1007/s41999-023-00858-y
pmc: PMC10587099
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
925-952Investigateurs
Jean Georges
(J)
Paolo Fusar-Poli
(P)
Marco Solmi
(M)
Javier Alonso Ramirez
(JA)
Mariana Alves
(M)
Gülistan Bahat
(G)
Jurgen Bauer
(J)
Ivan Bautman
(I)
Rui Buzaco
(R)
Álvaro Casas Herrero
(ÁC)
Matteo Cesari
(M)
Yaohua Chen
(Y)
Antonio Cherubini
(A)
Grazia Maria Corbi
(GM)
Alfonso Cruz Jentoft
(AC)
Anne-Marie De Cock
(AM)
Jacopo Demurtas
(J)
Burcu Balam Dogu
(BB)
Ellen Freiberger
(E)
Miriam L Haaksma
(ML)
Marina Kotsani
(M)
Sarah Lamb
(S)
Mounir Lamloum
(M)
Evelyne Liuu
(E)
Rene Melis
(R)
Laura Monica Perez Bazan
(LMP)
Maria Cristina Polidori
(MC)
Joan Ars Ricart
(JA)
Almudena Medina Rincon
(AM)
Yves Rolland
(Y)
Roman Romero-Ortuno
(R)
Guillaume Sacco
(G)
Mathias Schlögl
(M)
Daniel Schoene
(D)
Debbie Shapiro
(D)
Susan Shenkin
(S)
Cornel Sieber
(C)
Lee Smith
(L)
Pinar Soysal
(P)
Thomas Tannou
(T)
Nicola Veronese
(N)
Ozlem Yilmaz
(O)
Agar Brugiavini
(A)
Federica Limongi
(F)
Stefania Maggi
(S)
Olivier Bruyère
(O)
Daniel Pinto
(D)
Jean-Yves Reginster
(JY)
Mario Barbagallo
(M)
Nikos Christodoulou
(N)
Olga Karpenko
(O)
Andreas S Lappas
(AS)
Rodrigo Ramalho
(R)
Joao Duraes
(J)
Reinhold Schmidt
(R)
Kristian Steen Frederiksen
(KS)
Informations de copyright
© 2023. The Author(s).
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