Phages as delivery vehicles and phage display.

Applications Bacteriophage Delivery vehicle Phage display

Journal

Progress in molecular biology and translational science
ISSN: 1878-0814
Titre abrégé: Prog Mol Biol Transl Sci
Pays: Netherlands
ID NLM: 101498165

Informations de publication

Date de publication:
2023
Historique:
medline: 3 10 2023
pubmed: 29 9 2023
entrez: 28 9 2023
Statut: ppublish

Résumé

Bacteriophages (Phages in short) were introduced as the natural enemy of bacteria that may act as alternatives to antibiotics to overcome the challenge of antibiotic resistance. However, in the recent history of science, phages have been employed in different molecular tools and used in numerous therapeutic and diagnostic approaches. Furthermore, thanks to the phage`s highly specific host range limited to prokaryotes, phage particles can be used as safe delivery vehicles and display systems. In this chapter, different phage display systems are introduced, in addition to various applications of phage display as a molecular and therapeutic tool in developing vaccines, antibacterial, and anti-cancer treatments.

Identifiants

pubmed: 37770167
pii: S1877-1173(23)00072-8
doi: 10.1016/bs.pmbts.2023.03.013
pii:
doi:

Substances chimiques

Anti-Bacterial Agents 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

119-132

Informations de copyright

Copyright © 2023. Published by Elsevier Inc.

Auteurs

Salsabil Makky (S)

Center for Microbiology and Phage Therapy, Zewail City of Science and Technology, October Gardens, 6th of October City, Giza, Egypt.

Fatma Abdelrahman (F)

Center for Microbiology and Phage Therapy, Zewail City of Science and Technology, October Gardens, 6th of October City, Giza, Egypt.

Maheswaran Easwaran (M)

Department of Biomedical Engineering, Sethu Institute of Technology, Virudhunagar, Tamil Nadu, India.

Anan Safwat (A)

Center for Microbiology and Phage Therapy, Zewail City of Science and Technology, October Gardens, 6th of October City, Giza, Egypt.

Ayman El-Shibiny (A)

Center for Microbiology and Phage Therapy, Zewail City of Science and Technology, October Gardens, 6th of October City, Giza, Egypt; Faculty of Environmental Agricultural Sciences, Arish University, Arish, Egypt. Electronic address: aelshibiny@zewailcity.edu.eg.

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Classifications MeSH