Assessing the Severity of Cervical Dystonia: Ask the Doctor or Ask the Patient?
anxiety
cervical dystonia
depression
dystonia
patient‐reported outcome measure
rating scale
torticollis
Journal
Movement disorders clinical practice
ISSN: 2330-1619
Titre abrégé: Mov Disord Clin Pract
Pays: United States
ID NLM: 101630279
Informations de publication
Date de publication:
Sep 2023
Sep 2023
Historique:
received:
10
02
2023
revised:
04
05
2023
accepted:
11
06
2023
pmc-release:
03
08
2024
medline:
29
9
2023
pubmed:
29
9
2023
entrez:
29
9
2023
Statut:
epublish
Résumé
Assessing disease severity can be performed using either clinician-rated scales (CRS) or patient-rated outcome (PRO) tools. These two measures frequently demonstrate poor correlations. To determine if the correlation between a CRS and PRO for motor features of cervical dystonia (CD) improves by accounting for non-motor features. Subjects with CD (N = 209) were evaluated using a CRS (Toronto Western Spasmodic Torticollis Rating Scale, TWSTRS) and a PRO (Cervical Dystonia Impact Profile, CDIP-58). Linear regression revealed a weak correlation between the two measures, even when considering only the motor subscales of each. The strength of this relationship improved with a regression model that included non-motor symptoms of pain, depression, and disability. These results argue that the results of motor assessments in a PRO for CD cannot be fully appreciated without simultaneous assessment of non-motor co-morbidities. This conclusion might apply to other disorders, especially those with frequent non-motor co-morbidities.
Sections du résumé
Background
UNASSIGNED
Assessing disease severity can be performed using either clinician-rated scales (CRS) or patient-rated outcome (PRO) tools. These two measures frequently demonstrate poor correlations.
Objectives
UNASSIGNED
To determine if the correlation between a CRS and PRO for motor features of cervical dystonia (CD) improves by accounting for non-motor features.
Methods
UNASSIGNED
Subjects with CD (N = 209) were evaluated using a CRS (Toronto Western Spasmodic Torticollis Rating Scale, TWSTRS) and a PRO (Cervical Dystonia Impact Profile, CDIP-58).
Results
UNASSIGNED
Linear regression revealed a weak correlation between the two measures, even when considering only the motor subscales of each. The strength of this relationship improved with a regression model that included non-motor symptoms of pain, depression, and disability.
Conclusions
UNASSIGNED
These results argue that the results of motor assessments in a PRO for CD cannot be fully appreciated without simultaneous assessment of non-motor co-morbidities. This conclusion might apply to other disorders, especially those with frequent non-motor co-morbidities.
Identifiants
pubmed: 37772296
doi: 10.1002/mdc3.13827
pii: MDC313827
pmc: PMC10525044
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1399-1403Subventions
Organisme : NINDS NIH HHS
ID : U54 NS065701
Pays : United States
Organisme : NCATS NIH HHS
ID : U54 TR001456
Pays : United States
Informations de copyright
© 2023 International Parkinson and Movement Disorder Society.
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