Treating facial overfilled syndrome with impaired facial expression-Presenting clinical experience with ultrasound imaging.


Journal

Journal of cosmetic dermatology
ISSN: 1473-2165
Titre abrégé: J Cosmet Dermatol
Pays: England
ID NLM: 101130964

Informations de publication

Date de publication:
Dec 2023
Historique:
revised: 26 08 2023
received: 19 07 2023
accepted: 19 09 2023
medline: 4 12 2023
pubmed: 29 9 2023
entrez: 29 9 2023
Statut: ppublish

Résumé

Facial overfilled syndrome is an adverse event following minimally invasive soft tissue filler injections. It presents in most cases as excess midfacial volume and/or as unnatural smile which is difficult to detect due to the absence of standardized evaluation methods. To showcase how to identify, evaluate, and treat facial overfilled syndrome by utilizing facial ultrasound and simultaneous hyaluronidase injections. Twenty-eight consecutive patients (26 females, 2 males) were enrolled in this study in which facial ultrasound was performed to evaluate the location previously implanted filler material. The position of the oral commissure was objectively measured in relation to bony landmarks, and the severity of lateral canthal lines was assessed by independent and blinded raters. The material was identified in 35.7% inside the subdermal fatty layer, in 28.6% inside the deep supra-periosteal fatty layer, in 10.7% inside the fibrous layer deep to the subdermal fatty layer, whereas in 25.0%, the product was not possible to locate clearly inside one specific layer. On average, 81.6 I.U. [range: 75-150] of hyaluronidase were injected. Lateral canthal line severity was before the treatment 2.28 (1.4) and was after the hyaluronidase treatment 2.02 (1.3) with p = 0.578. The position of the oral commissure increased by 0.60 cm in vertical and by 0.30 cm in horizontal directions (both p < 0.001). Facial overfilled syndrome following aesthetic soft tissue filler injections can present as excess midfacial volume but also as unnatural smile. Targeted hyaluronidase injections into the culprit pockets inside the midfacial soft tissues have shown to re-establish a natural smile, to reduce excess midfacial volume, and to decrease lateral canthal line severity.

Sections du résumé

BACKGROUND BACKGROUND
Facial overfilled syndrome is an adverse event following minimally invasive soft tissue filler injections. It presents in most cases as excess midfacial volume and/or as unnatural smile which is difficult to detect due to the absence of standardized evaluation methods.
OBJECTIVE OBJECTIVE
To showcase how to identify, evaluate, and treat facial overfilled syndrome by utilizing facial ultrasound and simultaneous hyaluronidase injections.
METHODS METHODS
Twenty-eight consecutive patients (26 females, 2 males) were enrolled in this study in which facial ultrasound was performed to evaluate the location previously implanted filler material. The position of the oral commissure was objectively measured in relation to bony landmarks, and the severity of lateral canthal lines was assessed by independent and blinded raters.
RESULTS RESULTS
The material was identified in 35.7% inside the subdermal fatty layer, in 28.6% inside the deep supra-periosteal fatty layer, in 10.7% inside the fibrous layer deep to the subdermal fatty layer, whereas in 25.0%, the product was not possible to locate clearly inside one specific layer. On average, 81.6 I.U. [range: 75-150] of hyaluronidase were injected. Lateral canthal line severity was before the treatment 2.28 (1.4) and was after the hyaluronidase treatment 2.02 (1.3) with p = 0.578. The position of the oral commissure increased by 0.60 cm in vertical and by 0.30 cm in horizontal directions (both p < 0.001).
CONCLUSION CONCLUSIONS
Facial overfilled syndrome following aesthetic soft tissue filler injections can present as excess midfacial volume but also as unnatural smile. Targeted hyaluronidase injections into the culprit pockets inside the midfacial soft tissues have shown to re-establish a natural smile, to reduce excess midfacial volume, and to decrease lateral canthal line severity.

Identifiants

pubmed: 37772766
doi: 10.1111/jocd.16013
doi:

Substances chimiques

Hyaluronoglucosaminidase EC 3.2.1.35
Dermal Fillers 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

3252-3260

Informations de copyright

© 2023 The Authors. Journal of Cosmetic Dermatology published by Wiley Periodicals LLC.

Références

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Auteurs

Leonie Schelke (L)

Department of Dermatology, Erasmus University Medical Center, Rotterdam, The Netherlands.

Steven Harris (S)

Harris Clinic, Crouch Hall Road Surgery, London, UK.

Hugues Cartier (H)

Clinic of Dermatology, Arras, France.

Michael Alfertshofer (M)

Division of Hand, Plastic and Aesthetic Surgery, Ludwig-Maximilians-University Munich, Munich, Germany.

Marwah Doestzada (M)

Aestec, Amsterdam, The Netherlands.

Sebastian Cotofana (S)

Department of Dermatology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Centre for Cutaneous Research, Blizard Institute, Queen Mary University of London, London, UK.

Peter J Velthuis (PJ)

Department of Dermatology, Erasmus University Medical Center, Rotterdam, The Netherlands.

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Classifications MeSH