Fluorination Influences the Bioisostery of Myo-Inositol Pyrophosphate Analogs.

fluorine inositol pyrophosphates phosphoramidite phosphorylation protein structures

Journal

Chemistry (Weinheim an der Bergstrasse, Germany)
ISSN: 1521-3765
Titre abrégé: Chemistry
Pays: Germany
ID NLM: 9513783

Informations de publication

Date de publication:
01 Dec 2023
Historique:
received: 27 07 2023
medline: 4 12 2023
pubmed: 29 9 2023
entrez: 29 9 2023
Statut: ppublish

Résumé

Inositol pyrophosphates (PP-IPs) are densely phosphorylated messenger molecules involved in numerous biological processes. PP-IPs contain one or two pyrophosphate group(s) attached to a phosphorylated myo-inositol ring. 5PP-IP

Identifiants

pubmed: 37773020
doi: 10.1002/chem.202302426
pmc: PMC7615343
mid: EMS189741
doi:

Substances chimiques

Diphosphates 0
Inositol Phosphates 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e202302426

Subventions

Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : Intramural NIH HHS
ID : Z01 ES080046
Pays : United States
Organisme : Swiss National Science Foundation
ID : CRSII5_170925
Pays : Switzerland
Organisme : Wellcome Trust
ID : 101010
Pays : United Kingdom

Informations de copyright

© 2023 The Authors. Chemistry - A European Journal published by Wiley-VCH GmbH.

Références

Nat Chem Biol. 2011 Nov 27;8(1):111-6
pubmed: 22119861
Proc Natl Acad Sci U S A. 2020 Aug 11;117(32):19245-19253
pubmed: 32727897
Org Lett. 2009 Apr 2;11(7):1551-4
pubmed: 19253999
Medchemcomm. 2019 Jun 7;10(7):1165-1172
pubmed: 31391889
Biochem J. 2013 Aug 1;453(3):413-26
pubmed: 23682967
J Am Chem Soc. 2010 Jun 9;132(22):7617-25
pubmed: 20465217
Molecules. 2022 Feb 02;27(3):
pubmed: 35164270
Biomolecules. 2023 Jan 12;13(1):
pubmed: 36671538
Sci Adv. 2021 Apr 23;7(17):
pubmed: 33893105
FEBS Lett. 2013 Nov 1;587(21):3464-70
pubmed: 24021644
Nucleic Acids Res. 1998 Feb 15;26(4):1046-50
pubmed: 9461466
J Biol Chem. 2000 Apr 28;275(17):12730-6
pubmed: 10777568
Chem Rev. 2006 Sep;106(9):3868-935
pubmed: 16967924
Proc Natl Acad Sci U S A. 2020 Feb 18;117(7):3568-3574
pubmed: 32019887
Curr Opin Chem Biol. 2022 Oct;70:102177
pubmed: 35780751
Chem Sci. 2013 Jan;4(1):405-410
pubmed: 23378892
Angew Chem Int Ed Engl. 2014 Sep 1;53(36):9508-11
pubmed: 25044992
J Biol Chem. 2007 Oct 19;282(42):30763-75
pubmed: 17702752
Angew Chem Int Ed Engl. 2014 Jul 7;53(28):7192-7
pubmed: 24888434
Science. 2016 May 20;352(6288):986-90
pubmed: 27080106
Chem Sci. 2021 Jul 8;12(32):10696-10702
pubmed: 34476054
Chemistry. 2016 Jul 18;22(30):10284-93
pubmed: 27334601
Chemistry. 2023 Dec 1;29(67):e202302426
pubmed: 37773020
Biol Chem. 2012 Sep;393(9):979-98
pubmed: 22944697
Bioorg Med Chem Lett. 2007 Jan 1;17(1):183-8
pubmed: 17045478
Chemistry. 2016 Aug 22;22(35):12406-14
pubmed: 27460418
Chem Biol. 2014 May 22;21(5):689-99
pubmed: 24768307
FASEB J. 2021 Feb;35(2):e21275
pubmed: 33475202
Biochem J. 2013 Jun 15;452(3):369-79
pubmed: 23725456
Nat Immunol. 2011 Jun 19;12(8):752-60
pubmed: 21685907
Adv Biol Regul. 2020 Jan;75:100674
pubmed: 31776069
Proc Natl Acad Sci U S A. 2010 Sep 7;107(36):15693-8
pubmed: 20724659
Trends Biochem Sci. 2017 Mar;42(3):219-231
pubmed: 27876550
Curr Biol. 1999 Nov 18;9(22):1323-6
pubmed: 10574768
Angew Chem Int Ed Engl. 2017 Mar 6;56(11):2955-2959
pubmed: 28170152
Chem Biol. 2008 Mar;15(3):274-86
pubmed: 18355727
Science. 2004 Dec 17;306(5704):2101-5
pubmed: 15604408
Cell. 2010 Dec 10;143(6):897-910
pubmed: 21145457
J Biol Chem. 2009 Jan 16;284(3):1863-72
pubmed: 18981179
J Chem Inf Model. 2021 Feb 22;61(2):743-755
pubmed: 33544592
Chem Commun (Camb). 2012 Nov 28;48(92):11292-4
pubmed: 23032903
Chem Commun (Camb). 2015 Aug 14;51(63):12605-8
pubmed: 26153667
Proc Natl Acad Sci U S A. 2007 Sep 25;104(39):15305-10
pubmed: 17873058

Auteurs

Sarah Hostachy (S)

Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Robert-Rössle-Straße 10, 13125, Berlin, Germany.

Huanchen Wang (H)

Inositol Signaling Group, National Institutes of Health, Research Triangle Park, North Carolina, 27709, USA.

Guangning Zong (G)

Inositol Signaling Group, National Institutes of Health, Research Triangle Park, North Carolina, 27709, USA.

Katy Franke (K)

Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Robert-Rössle-Straße 10, 13125, Berlin, Germany.

Andrew M Riley (AM)

Medicinal Chemistry & Drug Discovery Department of Pharmacology, University of Oxford, Oxford, OX1 3QT, UK.

Peter Schmieder (P)

Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Robert-Rössle-Straße 10, 13125, Berlin, Germany.

Barry V L Potter (BVL)

Medicinal Chemistry & Drug Discovery Department of Pharmacology, University of Oxford, Oxford, OX1 3QT, UK.

Stephen B Shears (SB)

Inositol Signaling Group, National Institutes of Health, Research Triangle Park, North Carolina, 27709, USA.

Dorothea Fiedler (D)

Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Robert-Rössle-Straße 10, 13125, Berlin, Germany.
Institut für Chemie, Humboldt-Universität zu Berlin, Brook-Taylor-Str. 2, 12489, Berlin, Germany.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH