Triple Threat: HDV, HBV, HIV Coinfection.

Humans Hepatitis B virus Hepatitis Delta Virus HIV Infections / complications Carcinoma, Hepatocellular / epidemiology Coinfection Liver Neoplasms / epidemiology Hepatitis B / complications
Coinfection HDV HIV Hepatitis delta Liver disease Viral hepatitis

Journal

Clinics in liver disease
ISSN: 1557-8224
Titre abrégé: Clin Liver Dis
Pays: United States
ID NLM: 9710002

Informations de publication

Date de publication:
11 2023
Historique:
medline: 3 10 2023
pubmed: 2 10 2023
entrez: 1 10 2023
Statut: ppublish

Résumé

Hepatitis delta virus (HDV) only infects patients with hepatitis B virus (HBV) due to its reliance on HBV surface proteins to form its envelope. With shared routes of transmission, HDV coinfection is estimated to occur in 15% of patients with HIV and HBV. However, HDV is often underdiagnosed and may be missed particularly in people living with HIV (PLWH) who are already on antiretroviral therapy with anti-HBV activity and coincidental HBV suppression. At the same time, HDV causes the most severe form of chronic viral hepatitis and leads to faster progression of liver disease and hepatocellular carcinoma. Thus, increased recognition and effective treatment are paramount, and as novel treatment options approach global markets, the study of their efficacy in PLWH should be pursued.

Identifiants

DOI: 10.1016/j.cld.2023.05.010 PMID: 37778779
pubmed: 37778779
pii: S1089-3261(23)00070-3
doi: 10.1016/j.cld.2023.05.010
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

955-972

Informations de copyright

Copyright © 2023 Elsevier Inc. All rights reserved.

Auteurs

Debra W Yen (DW)

Division of Digestive Diseases, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA.

Vicente Soriano (V)

Health Sciences School & Medical Center, Universidad Internacional La Rioja (UNIR), Madrid, Spain.

Pablo Barreiro (P)

Public Health Regional Laboratory, Hospital Isabel Zendal, Universidad Rey Juan Carlos, Madrid, Spain.

Kenneth E Sherman (KE)

Division of Digestive Diseases, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA. Electronic address: Kenneth.Sherman@UC.edu.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Triple Threat: HDV, HBV, HIV Coinfection.
questionsmedicales.fr › Virus › Virus de l'hépatite › Hepadnaviridae › Orthohepadnavirus › Virus de l'hépatite B › Triple Threat: HDV, HBV, HIV Coinfection.
questionsmedicales.fr › Virus › Virus à ARN › Virus à ARN de polarité négative › Virus de l'hépatite delta › Triple Threat: HDV, HBV, HIV Coinfection.
questionsmedicales.fr › Maladies du système immunitaire › Déficits immunitaires › Infections à VIH › Triple Threat: HDV, HBV, HIV Coinfection.
questionsmedicales.fr › Maladies de l'appareil digestif › Maladies du foie › Tumeurs du foie › Carcinome hépatocellulaire › Triple Threat: HDV, HBV, HIV Coinfection.
questionsmedicales.fr › Infection › Co-infection › Triple Threat: HDV, HBV, HIV Coinfection.
questionsmedicales.fr › Maladies de l'appareil digestif › Maladies du foie › Tumeurs du foie › Triple Threat: HDV, HBV, HIV Coinfection.
questionsmedicales.fr › Maladies de l'appareil digestif › Maladies du foie › Hépatite › Hépatites virales humaines › Hépatite B › Triple Threat: HDV, HBV, HIV Coinfection.