Congenital thymoma.
Congenital Abnormalities
Hospitals, Pediatric
Thymoma
Thymus Hyperplasia
Thymus Neoplasms
Journal
Autopsy & case reports
ISSN: 2236-1960
Titre abrégé: Autops Case Rep
Pays: Brazil
ID NLM: 101640070
Informations de publication
Date de publication:
2021
2021
Historique:
received:
24
08
2020
accepted:
02
08
2021
medline:
22
9
2021
pubmed:
22
9
2021
entrez:
2
10
2023
Statut:
epublish
Résumé
Thymomas are a heterogeneous group of tumors arising from the epithelium of the thymus. They are categorized by the proportion of neoplastic epithelia to lymphocytes and by the degree of cytologic atypia. Thymomas constitute 0.2-1.5% of all malignancies and nearly all occur in patients over 20 years. We reviewed the available literature and found less than 50 cases of thymoma reported in children (<18 years of age), the youngest being 4 years old, and no cases in newborns. They represent less than 1% of all mediastinal tumors in children. Due to the limited number of cases in the pediatric population, the diagnosis and treatment in this population is extremely challenging. Thymomas in all age groups may be associated with paraneoplastic syndromes, being myasthenia gravis the most common, which is associated with a worse prognosis in the pediatric population. We present the first case of a newborn infant with congenital thymoma. This case demonstrates a rare tumor in an unusual age group and emphasizes the importance of multidisciplinary teamwork in the decision-making and management of this condition.
Identifiants
pubmed: 37780405
doi: 10.4322/acr.2021.327
pii: acrep080521_EN
pmc: PMC10538989
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
e2021327Informations de copyright
Copyright © 2021 The Author(s).
Déclaration de conflit d'intérêts
Conflict of interest: none
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