A Recurrent Mutation in Growth Hormone Receptor (

delayed puberty facial dysmorphism growth hormone insensitivity short stature truncal obesity widely-spaced breasts

Journal

The Yale journal of biology and medicine
ISSN: 1551-4056
Titre abrégé: Yale J Biol Med
Pays: United States
ID NLM: 0417414

Informations de publication

Date de publication:
09 2023
Historique:
medline: 3 10 2023
pubmed: 2 10 2023
entrez: 2 10 2023
Statut: epublish

Résumé

Laron syndrome (LS) is a rare autosomal recessively segregating disorder of severe short stature. The condition is characterized by short limbs, delayed puberty, hypoglycemia in infancy, and obesity. Mutations in growth hormone receptor (

Identifiants

pubmed: 37780997
doi: 10.59249/TCAA2040
pii: yjbm963313
pmc: PMC10524814
doi:

Substances chimiques

Receptors, Somatotropin 0

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

313-325

Informations de copyright

Copyright ©2023, Yale Journal of Biology and Medicine.

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Auteurs

Rana Muhammad Kamran Shabbir (RMK)

Department of Zoology, Division of Science and Technology, University of Education, Lahore, Pakistan.

Gökhan Nalbant (G)

Department of Molecular Biology and Genetics, MOBGAM, Istanbul Technical University, Istanbul, Türkiye.

Qamar Zaman (Q)

Human Genetics Program, Department of Zoology, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.

Aslıhan Tolun (A)

Department of Molecular Biology and Genetics, MOBGAM, Istanbul Technical University, Istanbul, Türkiye.

Sajid Malik (S)

Human Genetics Program, Department of Zoology, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.

Sara Mumtaz (S)

Department of Biological Sciences, National University of Medical Sciences, Rawalpindi, Pakistan.

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Classifications MeSH