Prognostic value of gender and primary tumor location in metastatic colon cancer.

Gender Metastatic colorectal cancer (mCRC) Prognosis RAS status Tumor location

Journal

Journal of Cancer
ISSN: 1837-9664
Titre abrégé: J Cancer
Pays: Australia
ID NLM: 101535920

Informations de publication

Date de publication:
2023
Historique:
received: 30 04 2023
accepted: 07 07 2023
medline: 2 10 2023
pubmed: 2 10 2023
entrez: 2 10 2023
Statut: epublish

Résumé

Sex might influence prognosis in patients affected by colorectal cancer. We retrospectively studied a cohort of patients affected by metastatic colon cancer (mCC) stratified by sex and primary tumor location. RAS mutational status was also included in the analysis. Overall, 616 patients met the eligibility criteria, 261 women and 355 men. Neither gender, nor RAS mutational status influenced overall survival (OS) in the entire population. As expected, patients with right-sided colon cancer (RCC) had a significant shorter OS compared to those with left-sided colon cancer (LCC) (21.3

Identifiants

DOI: 10.7150/jca.85748 PMID: 37781086 PMC: PMC10539565
pubmed: 37781086
doi: 10.7150/jca.85748
pii: jcav14p2751
pmc: PMC10539565
doi:

Types de publication

Journal Article

Langues

eng

Pagination

2751-2758

Informations de copyright

© The author(s).

Déclaration de conflit d'intérêts

Competing Interests: The authors have declared that no competing interest exists.

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Auteurs

Antonino Grassadonia (A)

Department of Innovative Technologies in Medicine and Dentistry, and Center for Advanced Studies and Technology (CAST), G. D'Annunzio University Chieti-Pescara, 66100 Chieti, Italy.

Erminia Carletti (E)

Department of Medical, Oral and Biotechnological Sciences, and Center for Advanced Studies and Technology (CAST), G. D'Annunzio University Chieti-Pescara, 66100 Chieti, Italy.

Antonella De Luca (A)

Department of Medical, Oral and Biotechnological Sciences, and Center for Advanced Studies and Technology (CAST), G. D'Annunzio University Chieti-Pescara, 66100 Chieti, Italy.

Patrizia Vici (P)

Unit of Phase IV Trials, IRCCS Regina Elena National Cancer Institute, 00144 Rome, Italy.

Francesca Sofia Di Lisa (FS)

Unit of Phase IV Trials, IRCCS Regina Elena National Cancer Institute, 00144 Rome, Italy.

Lorena Filomeno (L)

Unit of Phase IV Trials, IRCCS Regina Elena National Cancer Institute, 00144 Rome, Italy.

Giuseppe Cicero (G)

Department of Surgical, Oncological and Oral Sciences, Section of Medical Oncology, University of Palermo, 90133 Palermo, Italy.

Laura De Lellis (L)

Department of Pharmacy, G. D'Annunzio University, Chieti-Pescara, 66100 Chieti, Italy.

Serena Veschi (S)

Department of Pharmacy, G. D'Annunzio University, Chieti-Pescara, 66100 Chieti, Italy.

Rosalba Florio (R)

Department of Pharmacy, G. D'Annunzio University, Chieti-Pescara, 66100 Chieti, Italy.

Davide Brocco (D)

Department of Pharmacy, G. D'Annunzio University, Chieti-Pescara, 66100 Chieti, Italy.

Pietro Di Marino (P)

Clinical Oncology, S.S. Annunziata Hospital, 66100 Chieti, Italy.

Saverio Alberti (S)

Unit of Medical Genetics, Department of Biomedical Sciences-BIOMORF, University of Messina, 98125 Messina, Italy.

Teresa Gamucci (T)

Medical Oncology, Sandro Pertini Hospital, 00159 Rome, Italy.

Paola Borrelli (P)

Laboratory of Biostatistics, Department of Medical, Oral and Biotechnological Sciences, G. D'Annunzio University Chieti-Pescara, 66100 Chieti, Italy.

Alessandro Cama (A)

Department of Pharmacy, G. D'Annunzio University, Chieti-Pescara, 66100 Chieti, Italy.

Nicola Tinari (N)

Department of Medical, Oral and Biotechnological Sciences, and Center for Advanced Studies and Technology (CAST), G. D'Annunzio University Chieti-Pescara, 66100 Chieti, Italy.

Classifications MeSH