Restriction spectrum imaging with elastic image registration for automated evaluation of response to neoadjuvant therapy in breast cancer.

Dynamic contrast-enhanced MRI (DCE) and apparent diffusion coefficient (ADC) are currently used to evaluate treatment response of breast cancer. The purpose of the current study was to evaluate the three-component Restriction Spectrum Imaging model (RSI Breast cancer patients ( Ten patients experienced pCR. Prediction of non-pCR using ROC AUC (95% CI) for change in measured tumor size from pre-treatment time point to early-treatment time point was 0.65 (0.38-0.92) for the RSI The automatic RSI

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Copyright © 2023 Andreassen, Loubrie, Tong, Fang, Seibert, Wallace, Zare, Ojeda-Fournier, Kuperman, Hahn, Jerome, Bathen, Rodríguez-Soto, Dale and Rakow-Penner.

Déclaration de conflit d'intérêts

Author AMD is employed and holds equity in CorTechs Labs, Inc., and serves on its Scientific Advisory Board. He is a member of the Scientific Advisory Board of Human Longevity, Inc. Author RRP is a consultant of Human Longevity, Inc. She has equity interest in CorTechs Labs, Inc. and is on their Scientific Advisory Board, Inc. She has equity interest in Curemetrix and is on the Scientific Advisory Board of Imagine Scientific. Author TMS reports honoraria from Varian Medical Systems and WebMD; he has an equity interest in CorTechs Labs, Inc. and serves on its Scientific Advisory Board. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.