The prevalence of autism among children with albinism.

congenital and stationary retinal disease < RETINA genetic disease / congenital abnormalities < PEDIATRIC OPHTHALMOLOGY genetics < GENETICS molecular < GENETICS practice management < SOCIOECONOMICS AND EDUCATION IN MEDICINE/OPHTHALMOLOGY

Journal

European journal of ophthalmology
ISSN: 1724-6016
Titre abrégé: Eur J Ophthalmol
Pays: United States
ID NLM: 9110772

Informations de publication

Date de publication:
03 Oct 2023
Historique:
medline: 3 10 2023
pubmed: 3 10 2023
entrez: 3 10 2023
Statut: aheadofprint

Résumé

The association between Autism spectrum disorders (ASD) and visual impairment has been mentioned in the literature. The aim of our study was to investigate the prevalence of autism among children with albinism compared to the prevalence of ASD in children with visual impairment secondary to other causes. Retrospective study of children with albinism from January 2015 to December 2020. A control group was created with children with early onset visual impairment of similar visual range and age, secondary to diagnosis other than albinism. Patients with associated Autism were identified in both groups. Seven hundred and eight children aged 1-18 years with visual impairment were included in the study. 401 children had a diagnosis of albinism, of whom 14 were also diagnosed with ASD. In the control group, composed of 307 patients, only 3 had ASD (p: 0·03). The prevalence of ASD in patients with albinism was 1 in 28, while in children with visual impairment from other causes was 1 in 102. We aim to raise awareness of the higher prevalence of autism in children diagnosed with albinism in order to reach earlier diagnosis and support.

Sections du résumé

BACKGROUND BACKGROUND
The association between Autism spectrum disorders (ASD) and visual impairment has been mentioned in the literature. The aim of our study was to investigate the prevalence of autism among children with albinism compared to the prevalence of ASD in children with visual impairment secondary to other causes.
METHODS METHODS
Retrospective study of children with albinism from January 2015 to December 2020. A control group was created with children with early onset visual impairment of similar visual range and age, secondary to diagnosis other than albinism. Patients with associated Autism were identified in both groups.
RESULTS RESULTS
Seven hundred and eight children aged 1-18 years with visual impairment were included in the study. 401 children had a diagnosis of albinism, of whom 14 were also diagnosed with ASD. In the control group, composed of 307 patients, only 3 had ASD (p: 0·03).
CONCLUSIONS CONCLUSIONS
The prevalence of ASD in patients with albinism was 1 in 28, while in children with visual impairment from other causes was 1 in 102. We aim to raise awareness of the higher prevalence of autism in children diagnosed with albinism in order to reach earlier diagnosis and support.

Identifiants

pubmed: 37787167
doi: 10.1177/11206721231206091
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

11206721231206091

Déclaration de conflit d'intérêts

Declaration of conflicting interestsThe authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Auteurs

Stav Gunz (S)

Faculty of Medicine, Hebrew University of Jerusalem, Israel.

Irit Rozen-Knisbacher (I)

Department of Ophthalmology, Hadassah Medical Center, Jerusalem, Israel.

Anat Blumenfeld (A)

Department of Ophthalmology, Hadassah Medical Center, Jerusalem, Israel.

Karen Hendler (K)

Department of Ophthalmology, Hadassah Medical Center, Jerusalem, Israel.

Claudia Yahalom (C)

Faculty of Medicine, Hebrew University of Jerusalem, Israel.
Department of Ophthalmology, Hadassah Medical Center, Jerusalem, Israel.

Classifications MeSH