Chemotherapy regimen for recurrent uterine leiomyosarcoma.


Journal

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners
ISSN: 1477-092X
Titre abrégé: J Oncol Pharm Pract
Pays: England
ID NLM: 9511372

Informations de publication

Date de publication:
Mar 2024
Historique:
medline: 18 3 2024
pubmed: 3 10 2023
entrez: 3 10 2023
Statut: ppublish

Résumé

Uterine leiomyosarcoma is a rare gynecological malignancy, the limited literature indicated that doxorubicin alone or gemcitabine/docetaxel combination is the preferred chemotherapy regimen. Given the rarity of the disease and the lack of high-level clinical evidence, there is no consensus on the best treatment. We report a case of a patient with uterine leiomyosarcoma who recurred after adjustment treatment with doxorubicin, gemcitabine, docetaxel, and anlotinib; and required a new chemotherapy regimen. The follow-up chemotherapy regimen was doxorubicin-liposome 40 mg/m It is important to comprehensively consider the patient's condition, and fully consider the efficacy, dosage, and adverse reactions of the chemotherapy regimen to determine the appropriate plan, in order to achieve the best therapeutic benefits for patients.

Identifiants

pubmed: 37787402
doi: 10.1177/10781552231205203
doi:

Substances chimiques

Gemcitabine 0
Docetaxel 15H5577CQD
Deoxycytidine 0W860991D6
Doxorubicin 80168379AG

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

400-403

Déclaration de conflit d'intérêts

Declaration of conflicting interestsThe authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Auteurs

Fang Hu (F)

First People's Hospital of Tianshui, Tianshui City, Gansu Province, China.

Yiqing Ye (Y)

Women's Hospital School of Medicine Zhejiang University, Hangzhou City, Zhejiang Province, China.

Hazeera Begum (H)

Zhejiang University School of Medicine, Hangzhou City, Zhejiang Province, China.

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Classifications MeSH