Chemotherapy regimen for recurrent uterine leiomyosarcoma.
Female
Humans
Leiomyosarcoma
/ drug therapy
Gemcitabine
Docetaxel
/ therapeutic use
Deoxycytidine
Disease-Free Survival
Neoplasm Recurrence, Local
/ drug therapy
Uterine Neoplasms
/ drug therapy
Doxorubicin
/ adverse effects
Pelvic Neoplasms
/ drug therapy
Antineoplastic Combined Chemotherapy Protocols
Uterine leiomyosarcoma
adverse reactions
dacarbazine
doxorubicin liposomes
Journal
Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners
ISSN: 1477-092X
Titre abrégé: J Oncol Pharm Pract
Pays: England
ID NLM: 9511372
Informations de publication
Date de publication:
Mar 2024
Mar 2024
Historique:
medline:
18
3
2024
pubmed:
3
10
2023
entrez:
3
10
2023
Statut:
ppublish
Résumé
Uterine leiomyosarcoma is a rare gynecological malignancy, the limited literature indicated that doxorubicin alone or gemcitabine/docetaxel combination is the preferred chemotherapy regimen. Given the rarity of the disease and the lack of high-level clinical evidence, there is no consensus on the best treatment. We report a case of a patient with uterine leiomyosarcoma who recurred after adjustment treatment with doxorubicin, gemcitabine, docetaxel, and anlotinib; and required a new chemotherapy regimen. The follow-up chemotherapy regimen was doxorubicin-liposome 40 mg/m It is important to comprehensively consider the patient's condition, and fully consider the efficacy, dosage, and adverse reactions of the chemotherapy regimen to determine the appropriate plan, in order to achieve the best therapeutic benefits for patients.
Identifiants
pubmed: 37787402
doi: 10.1177/10781552231205203
doi:
Substances chimiques
Gemcitabine
0
Docetaxel
15H5577CQD
Deoxycytidine
0W860991D6
Doxorubicin
80168379AG
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
400-403Déclaration de conflit d'intérêts
Declaration of conflicting interestsThe authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.