Clinical Applications of Photon-counting CT: A Review of Pioneer Studies and a Glimpse into the Future.

Humans Tomography, X-Ray Computed Arteries Artifacts Bronchi Contrast Media

Journal

Radiology
ISSN: 1527-1315
Titre abrégé: Radiology
Pays: United States
ID NLM: 0401260

Informations de publication

Date de publication:
10 2023
Historique:
pmc-release: 01 10 2024
medline: 4 10 2023
pubmed: 3 10 2023
entrez: 3 10 2023
Statut: ppublish

Résumé

CT systems equipped with photon-counting detectors (PCDs), referred to as photon-counting CT (PCCT), are beginning to change imaging in several subspecialties, such as cardiac, vascular, thoracic, and musculoskeletal radiology. Evidence has been building in the literature underpinning the many advantages of PCCT for different clinical applications. These benefits derive from the distinct features of PCDs, which are made of semiconductor materials capable of converting photons directly into electric signal. PCCT advancements include, among the most important, improved spatial resolution, noise reduction, and spectral properties. PCCT spatial resolution on the order of 0.25 mm allows for the improved visualization of small structures (eg, small vessels, arterial walls, distal bronchi, and bone trabeculations) and their pathologies, as well as the identification of previously undetectable anomalies. In addition, blooming artifacts from calcifications, stents, and other dense structures are reduced. The benefits of the spectral capabilities of PCCT are broad and include reducing radiation and contrast material dose for patients. In addition, multiple types of information can be extracted from a single data set (ie, multiparametric imaging), including quantitative data often regarded as surrogates of functional information (eg, lung perfusion). PCCT also allows for a novel type of CT imaging, K-edge imaging. This technique, combined with new contrast materials specifically designed for this modality, opens the door to new applications for imaging in the future.

Identifiants

DOI: 10.1148/radiol.222432 PMID: 37787672 PMC: PMC10623209
pubmed: 37787672
doi: 10.1148/radiol.222432
pmc: PMC10623209
doi:

Substances chimiques

Contrast Media 0

Types de publication

Journal Article Review Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e222432

Subventions

Organisme : NIBIB NIH HHS
ID : R21 EB030373
Pays : United States

Informations de copyright

© RSNA, 2023.

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Auteurs

Philippe C Douek (PC)

From the University of Lyon, INSA-Lyon, Claude Bernard Lyon 1 University, UJM-Saint Etienne, CNRS, Inserm, Villeurbanne, France (P.C.D., L.B., S.A.S.M.); Department of Cardiovascular and Thoracic Radiology, Louis Pradel Hospital, Hospices Civils de Lyon, 59 Boulevard Pinel, 69500 Bron, France (P.C.D., S.B., L.B., S.A.S.M.); Claude Bernard Lyon 1 University, Villeurbanne, France (S.B.); Department of Radiology and Nuclear Medicine, Erasmus Medical Center, Rotterdam, the Netherlands (E.H.G.O., R.P.J.B.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.P.C.); Department of Radiology and Imaging Sciences, Emory University, Atlanta, Ga (A.P.); Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Ga (A.P.); and Winship Cancer Institute, Atlanta, Ga (A.P.).
ORCID: 0000-0002-5096-4698

Sara Boccalini (S)

From the University of Lyon, INSA-Lyon, Claude Bernard Lyon 1 University, UJM-Saint Etienne, CNRS, Inserm, Villeurbanne, France (P.C.D., L.B., S.A.S.M.); Department of Cardiovascular and Thoracic Radiology, Louis Pradel Hospital, Hospices Civils de Lyon, 59 Boulevard Pinel, 69500 Bron, France (P.C.D., S.B., L.B., S.A.S.M.); Claude Bernard Lyon 1 University, Villeurbanne, France (S.B.); Department of Radiology and Nuclear Medicine, Erasmus Medical Center, Rotterdam, the Netherlands (E.H.G.O., R.P.J.B.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.P.C.); Department of Radiology and Imaging Sciences, Emory University, Atlanta, Ga (A.P.); Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Ga (A.P.); and Winship Cancer Institute, Atlanta, Ga (A.P.).

Edwin H G Oei (EHG)

From the University of Lyon, INSA-Lyon, Claude Bernard Lyon 1 University, UJM-Saint Etienne, CNRS, Inserm, Villeurbanne, France (P.C.D., L.B., S.A.S.M.); Department of Cardiovascular and Thoracic Radiology, Louis Pradel Hospital, Hospices Civils de Lyon, 59 Boulevard Pinel, 69500 Bron, France (P.C.D., S.B., L.B., S.A.S.M.); Claude Bernard Lyon 1 University, Villeurbanne, France (S.B.); Department of Radiology and Nuclear Medicine, Erasmus Medical Center, Rotterdam, the Netherlands (E.H.G.O., R.P.J.B.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.P.C.); Department of Radiology and Imaging Sciences, Emory University, Atlanta, Ga (A.P.); Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Ga (A.P.); and Winship Cancer Institute, Atlanta, Ga (A.P.).
ORCID: 0000-0003-3727-3427

David P Cormode (DP)

From the University of Lyon, INSA-Lyon, Claude Bernard Lyon 1 University, UJM-Saint Etienne, CNRS, Inserm, Villeurbanne, France (P.C.D., L.B., S.A.S.M.); Department of Cardiovascular and Thoracic Radiology, Louis Pradel Hospital, Hospices Civils de Lyon, 59 Boulevard Pinel, 69500 Bron, France (P.C.D., S.B., L.B., S.A.S.M.); Claude Bernard Lyon 1 University, Villeurbanne, France (S.B.); Department of Radiology and Nuclear Medicine, Erasmus Medical Center, Rotterdam, the Netherlands (E.H.G.O., R.P.J.B.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.P.C.); Department of Radiology and Imaging Sciences, Emory University, Atlanta, Ga (A.P.); Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Ga (A.P.); and Winship Cancer Institute, Atlanta, Ga (A.P.).

Amir Pourmorteza (A)

From the University of Lyon, INSA-Lyon, Claude Bernard Lyon 1 University, UJM-Saint Etienne, CNRS, Inserm, Villeurbanne, France (P.C.D., L.B., S.A.S.M.); Department of Cardiovascular and Thoracic Radiology, Louis Pradel Hospital, Hospices Civils de Lyon, 59 Boulevard Pinel, 69500 Bron, France (P.C.D., S.B., L.B., S.A.S.M.); Claude Bernard Lyon 1 University, Villeurbanne, France (S.B.); Department of Radiology and Nuclear Medicine, Erasmus Medical Center, Rotterdam, the Netherlands (E.H.G.O., R.P.J.B.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.P.C.); Department of Radiology and Imaging Sciences, Emory University, Atlanta, Ga (A.P.); Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Ga (A.P.); and Winship Cancer Institute, Atlanta, Ga (A.P.).
ORCID: 0000-0001-7149-5424

Loic Boussel (L)

From the University of Lyon, INSA-Lyon, Claude Bernard Lyon 1 University, UJM-Saint Etienne, CNRS, Inserm, Villeurbanne, France (P.C.D., L.B., S.A.S.M.); Department of Cardiovascular and Thoracic Radiology, Louis Pradel Hospital, Hospices Civils de Lyon, 59 Boulevard Pinel, 69500 Bron, France (P.C.D., S.B., L.B., S.A.S.M.); Claude Bernard Lyon 1 University, Villeurbanne, France (S.B.); Department of Radiology and Nuclear Medicine, Erasmus Medical Center, Rotterdam, the Netherlands (E.H.G.O., R.P.J.B.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.P.C.); Department of Radiology and Imaging Sciences, Emory University, Atlanta, Ga (A.P.); Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Ga (A.P.); and Winship Cancer Institute, Atlanta, Ga (A.P.).
ORCID: 0000-0001-9053-8127

Salim A Si-Mohamed (SA)

From the University of Lyon, INSA-Lyon, Claude Bernard Lyon 1 University, UJM-Saint Etienne, CNRS, Inserm, Villeurbanne, France (P.C.D., L.B., S.A.S.M.); Department of Cardiovascular and Thoracic Radiology, Louis Pradel Hospital, Hospices Civils de Lyon, 59 Boulevard Pinel, 69500 Bron, France (P.C.D., S.B., L.B., S.A.S.M.); Claude Bernard Lyon 1 University, Villeurbanne, France (S.B.); Department of Radiology and Nuclear Medicine, Erasmus Medical Center, Rotterdam, the Netherlands (E.H.G.O., R.P.J.B.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.P.C.); Department of Radiology and Imaging Sciences, Emory University, Atlanta, Ga (A.P.); Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Ga (A.P.); and Winship Cancer Institute, Atlanta, Ga (A.P.).
ORCID: 0000-0003-0314-4010

Ricardo P J Budde (RPJ)

From the University of Lyon, INSA-Lyon, Claude Bernard Lyon 1 University, UJM-Saint Etienne, CNRS, Inserm, Villeurbanne, France (P.C.D., L.B., S.A.S.M.); Department of Cardiovascular and Thoracic Radiology, Louis Pradel Hospital, Hospices Civils de Lyon, 59 Boulevard Pinel, 69500 Bron, France (P.C.D., S.B., L.B., S.A.S.M.); Claude Bernard Lyon 1 University, Villeurbanne, France (S.B.); Department of Radiology and Nuclear Medicine, Erasmus Medical Center, Rotterdam, the Netherlands (E.H.G.O., R.P.J.B.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.P.C.); Department of Radiology and Imaging Sciences, Emory University, Atlanta, Ga (A.P.); Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Ga (A.P.); and Winship Cancer Institute, Atlanta, Ga (A.P.).
ORCID: 0000-0003-3792-615X

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Clinical Applications of Photon-counting CT: A...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Imagerie diagnostique › Tomographie › Tomographie à rayons X › Tomodensitométrie › Clinical Applications of Photon-counting CT: A...
questionsmedicales.fr › Système cardiovasculaire › Vaisseaux sanguins › Artères › Clinical Applications of Photon-counting CT: A...
questionsmedicales.fr › Techniques d'investigation › Artéfacts › Clinical Applications of Photon-counting CT: A...
questionsmedicales.fr › Appareil respiratoire › Poumon › Bronches › Clinical Applications of Photon-counting CT: A...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Produits de contraste › Clinical Applications of Photon-counting CT: A...