Functional outcome following intracapsular resection of head and neck peripheral nerve sheath tumors: a retrospective cohort.

En bloc resection Intracapsular resection Intraoperative nerve monitoring Peripheral nerve sheath tumor Schwannoma

Journal

Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
ISSN: 1916-0216
Titre abrégé: J Otolaryngol Head Neck Surg
Pays: England
ID NLM: 101479544

Informations de publication

Date de publication:
03 Oct 2023
Historique:
received: 27 12 2022
accepted: 29 05 2023
medline: 5 10 2023
pubmed: 4 10 2023
entrez: 3 10 2023
Statut: epublish

Résumé

Intracapsular resection of head and neck peripheral nerve sheath tumors (PNST) has emerged as a nerve-preserving technique compared to en bloc resection. The aim of this study was to evaluate and compare the functional outcome of both surgical techniques performed at a single tertiary referral center. This is a retrospective cohort of patients with head and neck PNST undergoing surgical resection from 2011 to 2021 at the Tel Aviv Sourasky Medical Center. Demographic data, the nerve of origin and surgical technique, including the use of intraoperative nerve monitoring were recorded and analyzed in association with postoperative functional outcomes. Overall, 25 patients who had a cervical or parapharyngeal PNST resected were included. Nerve function was preserved in 11 of 18 patients (61%) who underwent intracapsular resection, while all those who underwent en bloc resections inevitably suffered from neurologic deficits (100%, N = 7). Sympathetic chain origin and an apparent neurologic deficit pre-operatively were associated with postoperative neural compromise. Improved functional outcome can be anticipated following intracapsular resection of extracranial head and neck PNST compared to complete resection, particularly in asymptomatic patients.

Sections du résumé

BACKGROUND BACKGROUND
Intracapsular resection of head and neck peripheral nerve sheath tumors (PNST) has emerged as a nerve-preserving technique compared to en bloc resection. The aim of this study was to evaluate and compare the functional outcome of both surgical techniques performed at a single tertiary referral center.
METHODS METHODS
This is a retrospective cohort of patients with head and neck PNST undergoing surgical resection from 2011 to 2021 at the Tel Aviv Sourasky Medical Center. Demographic data, the nerve of origin and surgical technique, including the use of intraoperative nerve monitoring were recorded and analyzed in association with postoperative functional outcomes.
RESULTS RESULTS
Overall, 25 patients who had a cervical or parapharyngeal PNST resected were included. Nerve function was preserved in 11 of 18 patients (61%) who underwent intracapsular resection, while all those who underwent en bloc resections inevitably suffered from neurologic deficits (100%, N = 7). Sympathetic chain origin and an apparent neurologic deficit pre-operatively were associated with postoperative neural compromise.
CONCLUSION CONCLUSIONS
Improved functional outcome can be anticipated following intracapsular resection of extracranial head and neck PNST compared to complete resection, particularly in asymptomatic patients.

Identifiants

pubmed: 37789466
doi: 10.1186/s40463-023-00646-5
pii: 10.1186/s40463-023-00646-5
pmc: PMC10546627
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

65

Informations de copyright

© 2023. Canadian Society Of Otolaryngology-Head & Neck Surgery.

Références

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Auteurs

Liyona Kampel (L)

The Department of Otolaryngology Head & Neck Surgery and Maxillofacial Surgery, The Interdisciplinary Center for Head & Neck Surgical Oncology, Tel Aviv Sourasky Medical Center, 6 Weizman St, 6423906, Tel Aviv, Israel.

Marga Serafimova (M)

The Department of Neurosurgery, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, Affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Shaun Edalati (S)

The Department of Otolaryngology Head & Neck Surgery and Maxillofacial Surgery, The Interdisciplinary Center for Head & Neck Surgical Oncology, Tel Aviv Sourasky Medical Center, 6 Weizman St, 6423906, Tel Aviv, Israel.

Adi Brenner (A)

The Radiology and Neuroradiology Unit, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, Affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Razan Masarwy (R)

The Department of Otolaryngology Head & Neck Surgery and Maxillofacial Surgery, The Interdisciplinary Center for Head & Neck Surgical Oncology, Tel Aviv Sourasky Medical Center, 6 Weizman St, 6423906, Tel Aviv, Israel.

Anton Warshavsky (A)

The Department of Otolaryngology Head & Neck Surgery and Maxillofacial Surgery, The Interdisciplinary Center for Head & Neck Surgical Oncology, Tel Aviv Sourasky Medical Center, 6 Weizman St, 6423906, Tel Aviv, Israel.

Gilad Horowitz (G)

The Department of Otolaryngology Head & Neck Surgery and Maxillofacial Surgery, The Interdisciplinary Center for Head & Neck Surgical Oncology, Tel Aviv Sourasky Medical Center, 6 Weizman St, 6423906, Tel Aviv, Israel.

Yuval Shapira (Y)

The Department of Neurosurgery, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, Affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Nidal Muhanna (N)

The Department of Otolaryngology Head & Neck Surgery and Maxillofacial Surgery, The Interdisciplinary Center for Head & Neck Surgical Oncology, Tel Aviv Sourasky Medical Center, 6 Weizman St, 6423906, Tel Aviv, Israel. Nidalm@tlvmc.gov.il.

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