Evidence for a dissociation between moral reasoning and moral decision-making in Tourette syndrome.

Tourette syndrome moral decision-making moral reasoning inhibitory control

Journal

Journal of neuropsychology
ISSN: 1748-6653
Titre abrégé: J Neuropsychol
Pays: England
ID NLM: 101468753

Informations de publication

Date de publication:
03 Oct 2023
Historique:
revised: 11 07 2023
received: 05 12 2022
accepted: 22 09 2023
medline: 4 10 2023
pubmed: 4 10 2023
entrez: 4 10 2023
Statut: aheadofprint

Résumé

Despite the growing interest on how Tourette syndrome (TS) affects social cognition skills, this field remains to date relatively under-explored. Here, we aim to advance knowledge on the topic by studying moral decision-making and moral reasoning in a group of adolescents with TS and a group of healthy controls. Overall, we found higher endorsement (i.e. a greater 'yes' response rate) for utilitarian solutions of incidental and instrumental moral dilemmas in TS compared to controls. By contrast, we reported an overall higher tendency of TS individuals to apply principles described in the moral foundation questionnaire to establish whether something is morally right or wrong. Our results document intact moral reasoning in TS and suggest that a deficit in suppressing inappropriate behaviours and/or altered sense of agency might be responsible for their higher utilitarian moral decision-making.

Identifiants

pubmed: 37789746
doi: 10.1111/jnp.12350
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2023 The Authors. Journal of Neuropsychology published by John Wiley & Sons Ltd on behalf of The British Psychological Society.

Références

Albin, R. L. (2018). Tourette syndrome: A disorder of the social decision-making network. Brain, 141(2), 332-347.
Atkinson-Clement, C., Sofia, F., Fernandez-Egea, E., de Liege, A., Beranger, B., Klein, Y., Deniau, E., Roze, E., Hartmann, A., & Worbe, Y. (2020). Structural and functional abnormalities within sensori-motor and limbic networks underpin intermittent explosive symptoms in Tourette disorder. Journal of Psychiatric Research, 125, 1-6.
Cheung, M. Y., Shahed, J., & Jankovic, J. (2007). Malignant Tourette syndrome. Movement Disorders, 22(12), 1743-1750.
Eddy, C. M. (2018). Social cognition and self-other distinctions in neuropsychiatry: Insights from schizophrenia and Tourette syndrome. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 82, 69-85.
Eskine, K. J., Kacinik, N. A., & Prinz, J. J. (2011). A bad taste in the mouth: Gustatory disgust influences moral judgment. Psychological Science, 22(3), 295-299.
Graham, J., Nosek, B. A., Haidt, J., Iyer, R., Koleva, S., & Ditto, P. H. (2011). Mapping the moral domain. Journal of Personality and Social Psychology, 101(2), 366-385.
Grasso, G. M., Lucifora, C., Perconti, P., & Plebe, A. (2020). Integrating human acceptable morality in autonomous vehicles. Advances in Intelligent Systems and Computing, 1131, 41-45.
Haidt, J., & Joseph, C. (2004). Intuitive ethics: How innately prepared intuitions generate culturally variable virtues. Daedalus, 133, 55-66.
Haidt, J., McCauley, C., & Rozin, P. (1994). Individual differences in sensitivity to disgust: A scale sampling seven domains of disgust elicitors. Personality and Individual Differences, 16(5), 701-713.
Jackson, S. R., Parkinson, A., Jung, J., Ryan, S. E., Morgan, P. S., Hollis, C., & Jackson, G. M. (2011). Compensatory neural reorganization in Tourette syndrome. Current Biology, 21(7), 580-585.
Koenigs, M., Young, L., Adolphs, R., Tranel, D., Cushman, F., Hauser, M., & Damasio, A. (2007). Damage to the prefrontal cortex increases utilitarian moral judgements. Nature, 446(7138), 908-911.
Kurvits, L., Martino, D., & Ganos, C. (2020). Clinical features that evoke the concept of disinhibition in Tourette syndrome. Frontiers in Psychiatry, 11, 21.
Lotto, L., Manfrinati, A., & Sarlo, M. (2014). A new set of moral dilemmas: Norms for moral acceptability, decision times, and emotional salience. Journal of Behavioral Decision Making, 27, 57-65.
Lucifora, C., Grasso, G. M., Perconti, P., & Plebe, A. (2020). Moral dilemmas in self-driving cars. Rivista Internazionale di Filosofia e Psicologia, 11(2), 238-250.
Lucifora, C., Grasso, G. M., Perconti, P., & Plebe, A. (2021). Moral reasoning and automatic risk reaction during driving. Cognition, Technology and Work, 23(4), 705-713.
Lucifora, C., Martino, G., Curcuruto, A., Salehinejad, M. A., & Vicario, C. M. (2021). How self-control predicts moral decision making: An exploratory study on healthy participants. International Journal of Environmental Research and Public Health, 18(7), 3840.
Martino, D., Leckman, J. F., & Okun, M. S. (2022). Why some individuals with Tourette syndrome experience assault and perpetrate criminal behavior. JAMA Neurology, 79(5), 442-444.
Mataix-Cols, D., Virtanen, S., Sidorchuk, A., Fernández de la Cruz, L., Larsson, H., Lichtenstein, P., & Latvala, A. (2022). Association of tourette syndrome and chronic tic disorder with violent assault and criminal convictions. JAMA Neurology, 79(5), 459-467.
Metzlaff, J., Finis, J., Münchau, A., Müller-Vahl, K., Schnitzler, A., Bellebaum, C., Biermann-Ruben, K., & Niccolai, V. (2022). Altered performance monitoring in Tourette syndrome: An MEG investigation. Scientific Reports, 12(1), 8300.
Morand-Beaulieu, S., Grot, S., Lavoie, J., Leclerc, J. B., Luck, D., & Lavoie, M. E. (2017). The puzzling question of inhibitory control in Tourette syndrome: A meta-analysis. Neuroscience and Biobehavioral Reviews, 80, 240-262.
Piazza, J., & Landy, J. F. (2020). Folk beliefs about the relationships anger and disgust have with moral disapproval. Cognition and Emotion, 34(2), 229-241.
Russell, P. S., & Giner-Sorolla, R. (2013). Bodily moral disgust: What it is, how it is different from anger, and why it is an unreasoned emotion. Psychological Bulletin, 139(2), 328-351.
Senberg, A., Münchau, A., Münte, T., Beste, C., & Roessner, V. (2021). Swearing and coprophenomena - a multidimensional approach. Neuroscience and Biobehavioral Reviews, 126, 12-22.
Singer, H. S. (2013). Motor control, habits, complex motor stereotypies, and Tourette syndrome. Annals of the New York Academy of Sciences, 1304, 22-31.
Van Lancker, D., & Cummings, J. L. (1999). Expletives: Neurolinguistic and neurobehavioral perspectives on swearing. Brain Research. Brain Research Reviews, 31(1), 83-104.
Vicario, C. M. (2016). Emotional appraisal of moral dilemmas: What neuroimaging can tell about the disgust-morality link. The Journal of Neuroscience, 36(2), 263-264.
Vicario, C. M., Gulisano, M., Martino, D., & Rizzo, R. (2016). Timing recalibration in childhood Tourette syndrome associated with persistent pimozide treatment. Journal of Neuropsychology, 10(2), 211-222.
Vicario, C. M., Gulisano, M., Maugeri, N., Albin, R. L., & Rizzo, R. (2021). Moral decision-making in adolescents with Tourette syndrome. Movement Disorders, 36(9), 2205-2206.
Vicario, C. M., Gulisano, M., Maugeri, N., & Rizzo, R. (2020). Delay reward discounting in adolescents with Tourette's syndrome. Movement Disorders, 35(7), 1279-1280.
Vicario, C. M., Kuran, K. A., Rogers, R., & Rafal, R. D. (2018). The effect of hunger and satiety in the judgment of ethical violations. Brain and Cognition, 125, 32-36.
Vicario, C. M., & Lucifora, C. (2021). Neuroethics: What the study of brain disorders can tell about moral behavior. AIMS Neuroscience, 8(4), 543-547.
Vicario, C. M., Martino, D., Spata, F., Defazio, G., Giacchè, R., Martino, V., Rappo, G., Pepi, A. M., Silvestri, P. R., & Cardona, F. (2010). Time processing in children with Tourette's syndrome. Brain and Cognition, 73(1), 28-34.
Vicario, C. M., & Rafal, R. D. (2017). Relationship between body mass index and moral disapproval rating for ethical violations. Personality and Individual Differences, 104, 8-11.
Vicario, C. M., Rafal, R. D., di Pellegrino, G., Lucifora, C., Salehinejad, M. A., Nitsche, M. A., & Avenanti, A. (2022). Indignation for moral violations suppresses the tongue motor cortex: Preliminary TMS evidence. Social Cognitive and Affective Neuroscience, 17(1), 151-159.
Wright, A., Rickards, H., & Cavanna, A. E. (2012). Impulse-control disorders in gilles de la tourette syndrome. The Journal of Neuropsychiatry and Clinical Neurosciences, 2, 16-27.
Yu, J., Tseng, P., Hung, D. L., Wu, S. W., & Juan, C. H. (2015). Brain stimulation improves cognitive control by modulating medial-frontal activity and preSMA-vmPFC functional connectivity. Human Brain Mapping, 36(10), 4004-4015.
Zanatto, D., Chattington, M., & Noyes, J. (2021). Sense of agency in human-machine interaction. In H. Ayaz, U. Asgher, & L. Paletta (Eds.), Advances in Neuroergonomics and cognitive engineering. AHFE 2021. Lecture Notes in Networks and Systems (Vol. 259). Springer. https://doi.org/10.1007/978-3-030-80285-1_41
Zapparoli, L., Seghezzi, S., Devoto, F., Mariano, M., Banfi, G., Porta, M., & Paulesu, E. (2020). Altered sense of agency in Gilles de la Tourette syndrome: Behavioural, clinical and functional magnetic resonance imaging findings. Brain Communications, 2(2), fcaa204.

Auteurs

Carmelo Mario Vicario (CM)

Department of Cognitive Sciences, Psychology, Education and Cultural Studies, University of Messina, Messina, Italy.

Nicoletta Maugeri (N)

Child Neuropsychiatry Unit, Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy.

Chiara Lucifora (C)

STLab, ISTC-CNR, Rome, Italy.

Adriana Prato (A)

Department of Cognitive Sciences, Psychology, Education and Cultural Studies, University of Messina, Messina, Italy.
Child Neuropsychiatry Unit, Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy.

Massimo Mucciardi (M)

Department of Cognitive Sciences, Psychology, Education and Cultural Studies, University of Messina, Messina, Italy.

Davide Martino (D)

Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada.
Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada.
Alberta Children's Hospital Research Institute, University of Calgary, Calgary, Alberta, Canada.

Renata Rizzo (R)

Child Neuropsychiatry Unit, Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy.

Classifications MeSH