Development of a plant-based oral vaccine candidate against the bovine respiratory pathogen
Mannheimia haemolytica
agroinfiltration
bovine respiratory disease
molecular farming
mucosal immunity
oral vaccine
plant-made vaccine
Journal
Frontiers in plant science
ISSN: 1664-462X
Titre abrégé: Front Plant Sci
Pays: Switzerland
ID NLM: 101568200
Informations de publication
Date de publication:
2023
2023
Historique:
received:
30
06
2023
accepted:
07
08
2023
medline:
4
10
2023
pubmed:
4
10
2023
entrez:
4
10
2023
Statut:
epublish
Résumé
Bovine respiratory disease (BRD) affects feedlot cattle across North America, resulting in economic losses due to animal treatment and reduced performance. In an effort to develop a vaccine candidate targeting a primary bacterial agent contributing to BRD, we produced a tripartite antigen consisting of segments of the virulence factor Leukotoxin A (LktA) and lipoprotein PlpE from
Identifiants
pubmed: 37790785
doi: 10.3389/fpls.2023.1251046
pmc: PMC10542578
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1251046Informations de copyright
Copyright © 2023 His Majesty the King in Right of Canada, as represented by the Minister of Agriculture and Agri-Food Canada for the contribution of Angelo Kaldis, Muhammed Salah Uddin, Jose Ortiz Guluarte, Coby Martin, Trevor W. Alexander, Rima Menassa.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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