Species-differences in the in vitro biotransformation of trifluoroethene (HFO-1123).
19F-NMR
HFO-1123
In vitro biotransformation
LC–MS/MS
Mercapturic acid pathway
Trifluoroethene
β-Lyase
Journal
Archives of toxicology
ISSN: 1432-0738
Titre abrégé: Arch Toxicol
Pays: Germany
ID NLM: 0417615
Informations de publication
Date de publication:
12 2023
12 2023
Historique:
received:
02
08
2023
accepted:
30
08
2023
medline:
1
11
2023
pubmed:
4
10
2023
entrez:
4
10
2023
Statut:
ppublish
Résumé
1,1,2-Trifluoroethene (HFO-1123) is anticipated for use as a refrigerant with low global warming potential. Inhalation studies on HFO-1123 in rats indicated a low potential for toxicity (NOAELs ≥ 20,000 ppm). In contrast, single inhalation exposure of Goettingen
Identifiants
pubmed: 37792044
doi: 10.1007/s00204-023-03603-3
pii: 10.1007/s00204-023-03603-3
pmc: PMC10567879
doi:
Substances chimiques
trifluoroethene
Z2866M3Z1A
Acetylcysteine
WYQ7N0BPYC
Lyases
EC 4.-
Glutathione
GAN16C9B8O
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
3095-3111Commentaires et corrections
Type : ErratumIn
Informations de copyright
© 2023. The Author(s).
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