She didn't start the fire: Mammary duct epithelial cells suppress adipocyte thermogenesis.
Journal
Cell metabolism
ISSN: 1932-7420
Titre abrégé: Cell Metab
Pays: United States
ID NLM: 101233170
Informations de publication
Date de publication:
03 10 2023
03 10 2023
Historique:
received:
11
09
2023
revised:
11
09
2023
accepted:
12
09
2023
medline:
6
10
2023
pubmed:
5
10
2023
entrez:
4
10
2023
Statut:
ppublish
Résumé
Male and female mice display highly divergent responses to cold-induced thermogenic beiging of subcutaneous adipose tissues. Recently in Nature, Patel et al. showed that mammary duct epithelial cells respond to cold-induced sympathetic activity, triggering the secretion of lipocalin 2 (LCN2) to inhibit thermogenic differentiation of adjacent mammary adipocytes.
Identifiants
pubmed: 37793344
pii: S1550-4131(23)00338-8
doi: 10.1016/j.cmet.2023.09.007
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1679-1680Informations de copyright
Copyright © 2023. Published by Elsevier Inc.
Déclaration de conflit d'intérêts
Declaration of interests The author declares no competing interests.