Voice analysis results in individuals with Alzheimer's disease: How do age and cognitive status affect voice parameters?
Alzheimer's disease
cognitive
dementia
voice analysis
voice disorders
voice therapy
Journal
Brain and behavior
ISSN: 2162-3279
Titre abrégé: Brain Behav
Pays: United States
ID NLM: 101570837
Informations de publication
Date de publication:
11 2023
11 2023
Historique:
revised:
17
09
2023
received:
10
08
2023
accepted:
23
09
2023
medline:
13
11
2023
pubmed:
5
10
2023
entrez:
5
10
2023
Statut:
ppublish
Résumé
Reports of acoustic changes in the voice in individuals with Alzheimer's disease (AD) and the relationship of acoustic changes with age and cognitive status are still limited. This study aims to determine the changes in voice analysis results in AD, as well as the effects of age and cognitive status on voice parameters. The study included 47 (AD: 30; healthy: 17) women with a mean age of 76.13 years. The acoustic voice parameters mean fundamental frequency (F0), relative average perturbation (RAP), jitter percent (Jitt), shimmer percent (Shim), and noise-to-harmonic ratio were detected. The mini-mental state examination (MMSE) was utilized. F0, Shim, Jitt, and RAP values were found to be statistically significantly higher in individuals with AD compared to healthy individuals. There was a significant negative correlation between MMSE and F0, Jitt, RAP and Shim, and the MMSE score had a significant negative effect on F0, Jitt, and RAP (p < .05). Cognitive status was discovered to significantly impact the voice, with fundamental frequency and frequency and amplitude perturbations increasing as cognitive level decreases. In order to contribute to the therapy process for voice disorders, cognitive functions can be focused on in addition to voice therapy.
Sections du résumé
BACKGROUND
Reports of acoustic changes in the voice in individuals with Alzheimer's disease (AD) and the relationship of acoustic changes with age and cognitive status are still limited.
OBJECTIVE
This study aims to determine the changes in voice analysis results in AD, as well as the effects of age and cognitive status on voice parameters.
METHODS
The study included 47 (AD: 30; healthy: 17) women with a mean age of 76.13 years. The acoustic voice parameters mean fundamental frequency (F0), relative average perturbation (RAP), jitter percent (Jitt), shimmer percent (Shim), and noise-to-harmonic ratio were detected. The mini-mental state examination (MMSE) was utilized.
RESULTS
F0, Shim, Jitt, and RAP values were found to be statistically significantly higher in individuals with AD compared to healthy individuals. There was a significant negative correlation between MMSE and F0, Jitt, RAP and Shim, and the MMSE score had a significant negative effect on F0, Jitt, and RAP (p < .05).
CONCLUSION
Cognitive status was discovered to significantly impact the voice, with fundamental frequency and frequency and amplitude perturbations increasing as cognitive level decreases. In order to contribute to the therapy process for voice disorders, cognitive functions can be focused on in addition to voice therapy.
Identifiants
pubmed: 37794703
doi: 10.1002/brb3.3271
pmc: PMC10636380
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e3271Informations de copyright
© 2023 The Authors. Brain and Behavior published by Wiley Periodicals LLC.
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