Single-cell sequencing of tumor-associated macrophages in a

Drosophila melanogaster ScRNA-seq hemocyte macrophages single-cell transcriptomics tumor model

Journal

Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960

Informations de publication

Date de publication:
2023
Historique:
received: 21 06 2023
accepted: 31 08 2023
medline: 6 10 2023
pubmed: 5 10 2023
entrez: 5 10 2023
Statut: epublish

Résumé

Tumor-associated macrophages may act to either limit or promote tumor growth, yet the molecular basis for either path is poorly characterized. We use a larval We identified five distinct hemocyte clusters. In addition to Ras

Identifiants

pubmed: 37795097
doi: 10.3389/fimmu.2023.1243797
pmc: PMC10546068
doi:

Substances chimiques

Drosophila Proteins 0
Caspases EC 3.4.22.-

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1243797

Informations de copyright

Copyright © 2023 Khalili, Mohammed, Kunc, Sindlerova, Ankarklev and Theopold.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Références

Nat Commun. 2020 Sep 8;11(1):4483
pubmed: 32900993
Nat Protoc. 2014 Jan;9(1):171-81
pubmed: 24385147
Innovation (Camb). 2021 Jul 01;2(3):100141
pubmed: 34557778
Curr Biol. 2016 Mar 7;26(5):575-84
pubmed: 26898463
Cancer Sci. 2020 Aug;111(8):2726-2735
pubmed: 32437078
Front Oncol. 2023 Apr 28;13:1170122
pubmed: 37188187
Elife. 2015 Feb 04;4:
pubmed: 25650737
Cytometry A. 2016 Jun;89(6):594-600
pubmed: 27144818
Microbiol Spectr. 2023 Feb 27;:e0367122
pubmed: 36847501
Cell. 2013 Oct 10;155(2):435-47
pubmed: 24075010
Bioinformatics. 2013 Jan 1;29(1):15-21
pubmed: 23104886
Cell Rep. 2022 Apr 19;39(3):110718
pubmed: 35443185
Biochem Biophys Res Commun. 2018 Nov 2;505(3):726-732
pubmed: 30292413
Sci Rep. 2016 Jun 10;6:27680
pubmed: 27282340
J Mol Biol. 2022 Feb 28;434(4):167333
pubmed: 34756921
Bioinformatics. 2015 Jan 15;31(2):166-9
pubmed: 25260700
Nat Rev Cancer. 2021 Nov;21(11):687-700
pubmed: 34389815
Sci Rep. 2020 Aug 31;10(1):14333
pubmed: 32868786
Nat Biotechnol. 2020 Dec;38(12):1408-1414
pubmed: 32747759
Insect Biochem Mol Biol. 2019 Jun;109:63-71
pubmed: 30974174
Philos Trans R Soc Lond B Biol Sci. 2018 Jan 5;373(1737):
pubmed: 29158317
J Genet Genomics. 2020 Apr 20;47(4):175-186
pubmed: 32487456
BMC Biol. 2015 Oct 01;13:81
pubmed: 26437768
Biol Open. 2014 Apr 15;3(4):250-60
pubmed: 24659248
Front Immunol. 2019 Jul 03;10:1462
pubmed: 31333642
Cancers (Basel). 2022 May 31;14(11):
pubmed: 35681725
Front Immunol. 2022 Jul 28;13:891220
pubmed: 35967383
Cell. 2021 Jun 24;184(13):3573-3587.e29
pubmed: 34062119
Elife. 2020 May 12;9:
pubmed: 32396065
Front Immunol. 2020 Jan 31;11:63
pubmed: 32082322
Cell Death Differ. 2017 Aug;24(8):1390-1400
pubmed: 28362431
Int J Mol Sci. 2022 Jan 25;23(3):
pubmed: 35163253
Cancers (Basel). 2021 Jun 29;13(13):
pubmed: 34209840
J Innate Immun. 2022;14(1):51-68
pubmed: 34247159
Int J Mol Sci. 2021 Dec 21;23(1):
pubmed: 35008434
Cell Res. 2015 Jul;25(7):771-84
pubmed: 26045163
Nat Methods. 2017 Apr;14(4):381-387
pubmed: 28263961
Nucleic Acids Res. 2018 Jan 4;46(D1):D809-D815
pubmed: 29069479
Curr Biol. 2020 Mar 23;30(6):R246-R248
pubmed: 32208142
Cell. 2018 Mar 22;173(1):275
pubmed: 29570995
J Innate Immun. 2021;13(6):376-390
pubmed: 34000729
Sci Adv. 2020 Jan 01;6(1):eaay6354
pubmed: 31911950
PLoS Pathog. 2016 Jul 14;12(7):e1005746
pubmed: 27414410
Dis Model Mech. 2008 Sep-Oct;1(2-3):144-54; discussion 153
pubmed: 19048077
Cell. 2018 Jan 11;172(1-2):262-274.e11
pubmed: 29328915
Elife. 2020 Dec 24;9:
pubmed: 33357377
Elife. 2020 Dec 30;9:
pubmed: 33377870

Auteurs

Dilan Khalili (D)

The Wenner-Gren Institute, Department of Molecular Biosciences, Stockholm University, Stockholm, Sweden.

Mubasher Mohammed (M)

The Wenner-Gren Institute, Department of Molecular Biosciences, Stockholm University, Stockholm, Sweden.

Martin Kunc (M)

The Wenner-Gren Institute, Department of Molecular Biosciences, Stockholm University, Stockholm, Sweden.
Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.

Martina Sindlerova (M)

The Wenner-Gren Institute, Department of Molecular Biosciences, Stockholm University, Stockholm, Sweden.

Johan Ankarklev (J)

The Wenner-Gren Institute, Department of Molecular Biosciences, Stockholm University, Stockholm, Sweden.

Ulrich Theopold (U)

The Wenner-Gren Institute, Department of Molecular Biosciences, Stockholm University, Stockholm, Sweden.

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Classifications MeSH