Increased 68 Ga-FAPI Activity in Primary Small Cell Neuroendocrine Carcinoma of the Gallbladder.


Journal

Clinical nuclear medicine
ISSN: 1536-0229
Titre abrégé: Clin Nucl Med
Pays: United States
ID NLM: 7611109

Informations de publication

Date de publication:
01 Nov 2023
Historique:
medline: 10 10 2023
pubmed: 5 10 2023
entrez: 5 10 2023
Statut: ppublish

Résumé

Primary small cell neuroendocrine carcinomas are extremely rare heterogeneous neoplasms. We present 68 Ga-FAPI (fibroblast activation protein inhibitor) PET/CT findings of small cell neuroendocrine carcinoma of the gallbladder in a 57-year-old woman. This rare gallbladder small cell neuroendocrine carcinoma demonstrated intense tracer uptake on 68 Ga-FAPI PET/CT. This demonstrates the potential value of 68 Ga-FAPI PET/CT for evaluation of gallbladder small cell neuroendocrine carcinoma.

Identifiants

pubmed: 37796160
doi: 10.1097/RLU.0000000000004855
pii: 00003072-202311000-00028
doi:

Substances chimiques

Gallium-68 98B30EPP5S
Fluorodeoxyglucose F18 0Z5B2CJX4D

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1003-1005

Informations de copyright

Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.

Déclaration de conflit d'intérêts

Conflicts of interest and sources of funding: This work was supported by the Natural Science Foundation of Chongqing (CSTB2022NSCQ-MSX1004).

Références

Wang Y, Huang B, Fu Q, et al. Comprehensive clinical analysis of gallbladder neuroendocrine neoplasms: a large-volume multicenter study during one decade. Ann Surg Oncol . 2022;29:7619–7630.
Faraoun SA, Guerrache Y, Dautry R, et al. Computed tomographic features of primary small cell neuroendocrine tumors of the gallbladder. J Comput Assist Tomogr . 2018;42:707–713.
Sharma P, Singh SS, Gayana S. Fibroblast activation protein inhibitor PET/CT: a promising molecular imaging tool. Clin Nucl Med . 2021;46:e141–e150.
Ou L, Zhou Y, Sun R, et al. Increased 68 Ga-FAPI activity in hepatic inflammatory myofibroblastoma. Clin Nucl Med . 2023;48:522–524.
Sun R, Huang Z, Wei J, et al. 68 Ga-FAPI and 18 F-FDG PET/CT findings in a patient with pancreatic tuberculosis mimicking malignant tumor. Clin Nucl Med . 2022;47:653–654.
Zhang Z, Dong H, Zhang L, et al. Xanthogranulomatous cholecystitis masquerading as gallbladder carcinoma on 68 Ga-FAPI-04 PET. Clin Nucl Med . 2022;47:895–896.
Peng D, Yang X, Yan Q, et al. Increased 68 Ga-FAPI uptake in psammomatous meningioma in a patient with gallbladder cancer. Clin Nucl Med . 2023;48:73–74.
Ting YY, John A, Maddern G, et al. Small cell neuroendocrine carcinoma of the gallbladder. ANZ J Surg . 2021;91:E357–E359.
Wang W, Yang CX, Yu XZ, et al. Clinicopathological characteristics and prognostic factors of patients with primary gallbladder neuroendocrine carcinomas. J Dig Dis . 2022;23:166–173.
Kepil N, Akinci O, Batur S, et al. A rare tumor of the gallbladder: small cell neuroendocrine carcinoma. North Clin Istanb . 2020;7:624–627.
Fichman V, Marques de Macedo P, Francis Saraiva Freitas D, et al. Zoonotic sporotrichosis in renal transplant recipients from Rio de Janeiro, Brazil. Transpl Infect Dis . 2021;23:e13485.

Auteurs

Longlan Chen (L)

From the Department of Nuclear Medicine, Chongqing University Cancer Hospital, Chongqing.

Lisheng Liu (L)

From the Department of Nuclear Medicine, Chongqing University Cancer Hospital, Chongqing.

Jun Hua (J)

From the Department of Nuclear Medicine, Chongqing University Cancer Hospital, Chongqing.

Xiaoliang Chen (X)

From the Department of Nuclear Medicine, Chongqing University Cancer Hospital, Chongqing.

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Classifications MeSH