The Importance of Incorporating Proportional Alignment in Adult Cervical Deformity Corrections Relative to Regional and Global Alignment: Steps Toward Development of a Cervical-Specific Score.


Journal

Spine
ISSN: 1528-1159
Titre abrégé: Spine (Phila Pa 1976)
Pays: United States
ID NLM: 7610646

Informations de publication

Date de publication:
05 Oct 2023
Historique:
received: 17 07 2022
accepted: 19 09 2023
medline: 5 10 2023
pubmed: 5 10 2023
entrez: 5 10 2023
Statut: aheadofprint

Résumé

The Global Alignment and Proportion(GAP) Score is widely used in adult spinal deformity surgery. However, it is not specific to the parameters used in adult cervical deformity(ACD). Create a cervicothoracic alignment and proportion(CAP) score in operative ACD patients. Retrospective single-center study. ACD patients with two-year(2Y) data were included. Parameters consisted of: relative McGregor's Slope[RMGS =(MGS*1.5)/0.9], relative cervical lordosis[RCL=CL - Thoracic Kyphosis(TK)], Cervical Lordosis Distribution Index(CLDI=C2-Apex*100/C2-T2), relative pelvic version(RPV=SS - PI*0.59+9), and a frailty factor(greater than 0.33). Cutoff points were chosen where the cross-tabulation of parameter subgroups reached maximal rate of meeting Optimal Outcome. Optimal outcome was defined as meeting Good Clinical Outcome(GCO) criteria without occurrence of distal junctional failure(DJF) or reoperation. CAP was scored between 0-13 and categorized accordingly: ≤3(Proportioned), 4-6(Moderately Disproportioned), >6(Severely Disproportioned). Multivariable logistic regression analysis determined the relationship between CAP categories, overall score and development of distal junctional kyphosis(DJK), DJF, reoperation, and Optimal Outcome by two years. 105 operative ACD patients were included. Assessment of three-month CAP score found a mean of 5.2/13 possible points. There were 22.7% of patients who were proportioned, 49.5% moderately disproportioned, and 27.8% severely disproportioned. DJK occurred in 34.5% and DJF in 8.7% DJF, 20.0% underwent reoperation, and 55.7% achieved Optimal Outcome. Patients severely disproportioned in CAP had higher odds of DJK (OR: 6.0,[2.1-17.7];P=0.001), DJF (OR: 9.7[1.8-51.8];P=0.008), reoperation(OR: 3.3,[1.9-10.6];P=0.011), and lower odds of meeting the optimal outcome(OR: 0.3,[0.1-0.7]; P=0.007) by two years, while Proportioned patients suffered zero occurrences of DJK or DJF. The regional alignment and proportion score is a method of analyzing the cervical spine relative to global alignment and demonstrates the importance of maintaining horizontal gaze, while also matching overall cervical and thoracolumbar alignment to limit complications and maximize clinical improvement.

Sections du résumé

BACKGROUND BACKGROUND
The Global Alignment and Proportion(GAP) Score is widely used in adult spinal deformity surgery. However, it is not specific to the parameters used in adult cervical deformity(ACD).
PURPOSE OBJECTIVE
Create a cervicothoracic alignment and proportion(CAP) score in operative ACD patients.
STUDY DESIGN/SETTING METHODS
Retrospective single-center study.
METHODS METHODS
ACD patients with two-year(2Y) data were included. Parameters consisted of: relative McGregor's Slope[RMGS =(MGS*1.5)/0.9], relative cervical lordosis[RCL=CL - Thoracic Kyphosis(TK)], Cervical Lordosis Distribution Index(CLDI=C2-Apex*100/C2-T2), relative pelvic version(RPV=SS - PI*0.59+9), and a frailty factor(greater than 0.33). Cutoff points were chosen where the cross-tabulation of parameter subgroups reached maximal rate of meeting Optimal Outcome. Optimal outcome was defined as meeting Good Clinical Outcome(GCO) criteria without occurrence of distal junctional failure(DJF) or reoperation. CAP was scored between 0-13 and categorized accordingly: ≤3(Proportioned), 4-6(Moderately Disproportioned), >6(Severely Disproportioned). Multivariable logistic regression analysis determined the relationship between CAP categories, overall score and development of distal junctional kyphosis(DJK), DJF, reoperation, and Optimal Outcome by two years.
RESULTS RESULTS
105 operative ACD patients were included. Assessment of three-month CAP score found a mean of 5.2/13 possible points. There were 22.7% of patients who were proportioned, 49.5% moderately disproportioned, and 27.8% severely disproportioned. DJK occurred in 34.5% and DJF in 8.7% DJF, 20.0% underwent reoperation, and 55.7% achieved Optimal Outcome. Patients severely disproportioned in CAP had higher odds of DJK (OR: 6.0,[2.1-17.7];P=0.001), DJF (OR: 9.7[1.8-51.8];P=0.008), reoperation(OR: 3.3,[1.9-10.6];P=0.011), and lower odds of meeting the optimal outcome(OR: 0.3,[0.1-0.7]; P=0.007) by two years, while Proportioned patients suffered zero occurrences of DJK or DJF.
CONCLUSION CONCLUSIONS
The regional alignment and proportion score is a method of analyzing the cervical spine relative to global alignment and demonstrates the importance of maintaining horizontal gaze, while also matching overall cervical and thoracolumbar alignment to limit complications and maximize clinical improvement.

Identifiants

pubmed: 37796161
doi: 10.1097/BRS.0000000000004843
pii: 00007632-990000000-00480
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.

Déclaration de conflit d'intérêts

Funding: No funding was obtained for the current work. Conflicts of interest outside this study are reported below.

Auteurs

Peter G Passias (PG)

Departments of Orthopaedic and Neurological Surgery, NYU Langone Orthopedic Hospital; New York Spine Institute, New York, NY, USA.

Tyler K Williamson (TK)

Departments of Orthopaedic and Neurological Surgery, NYU Langone Orthopedic Hospital; New York Spine Institute, New York, NY, USA.

Katherine E Pierce (KE)

Departments of Orthopaedic and Neurological Surgery, NYU Langone Orthopedic Hospital; New York Spine Institute, New York, NY, USA.

Andrew J Schoenfeld (AJ)

Department of Orthopedic Surgery, Brigham and Women's Center for Surgery and Public Health, Boston, MA, USA.

Oscar Krol (O)

Departments of Orthopaedic and Neurological Surgery, NYU Langone Orthopedic Hospital; New York Spine Institute, New York, NY, USA.

Bailey Imbo (B)

Departments of Orthopaedic and Neurological Surgery, NYU Langone Orthopedic Hospital; New York Spine Institute, New York, NY, USA.

Rachel Joujon-Roche (R)

Departments of Orthopaedic and Neurological Surgery, NYU Langone Orthopedic Hospital; New York Spine Institute, New York, NY, USA.

Peter Tretiakov (P)

Departments of Orthopaedic and Neurological Surgery, NYU Langone Orthopedic Hospital; New York Spine Institute, New York, NY, USA.

Salman Ahmad (S)

Departments of Orthopaedic and Neurological Surgery, NYU Langone Orthopedic Hospital; New York Spine Institute, New York, NY, USA.

Claudia Bennett-Caso (C)

Departments of Orthopaedic and Neurological Surgery, NYU Langone Orthopedic Hospital; New York Spine Institute, New York, NY, USA.

Jamshaid Mir (J)

Departments of Orthopaedic and Neurological Surgery, NYU Langone Orthopedic Hospital; New York Spine Institute, New York, NY, USA.

Pooja Dave (P)

Departments of Orthopaedic and Neurological Surgery, NYU Langone Orthopedic Hospital; New York Spine Institute, New York, NY, USA.

Kimberly McFarland (K)

Departments of Orthopaedic and Neurological Surgery, NYU Langone Orthopedic Hospital; New York Spine Institute, New York, NY, USA.

Stephane Owusu-Sarpong (S)

Department of Orthopaedic Surgery, NYU Langone Orthopedic Hospital, New York, New York, USA.

Jordan A Lebovic (JA)

Department of Orthopaedic Surgery, NYU Langone Orthopedic Hospital, New York, New York, USA.

M Burhan Janjua (MB)

Department of Neurotrauma, Neuro-oncology, and Spine, Mercy Health, Chicago, IL, USA.

Rafael de la Garza-Ramos (R)

Department of Neurological Surgery, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, NY, USA.

Shaleen Vira (S)

Department of Orthopaedic Surgery, UT Southwestern Medical Center, Dallas, TX, USA.

Bassel Diebo (B)

Department of Orthopedic Surgery, SUNY Downstate Medical Center, Brooklyn, NY, USA.

Heiko Koller (H)

International Center for Spinal Disorders and Deformity, Orthopedic Department II, Asklepios Clinics Bad Abbach, Germany.

Themistocles S Protopsaltis (TS)

Department of Orthopaedic Surgery, NYU Langone Orthopedic Hospital, New York, New York, USA.

Renaud Lafage (R)

Department of Orthopaedic Surgery, Lenox Hill Hospital; New York, NY, USA.

Virginie Lafage (V)

Department of Orthopaedic Surgery, Lenox Hill Hospital; New York, NY, USA.

Classifications MeSH