Theranostic Nuclear Medicine with Gallium-68, Lutetium-177, Copper-64/67, Actinium-225, and Lead-212/203 Radionuclides.
Journal
Chemical reviews
ISSN: 1520-6890
Titre abrégé: Chem Rev
Pays: United States
ID NLM: 2985134R
Informations de publication
Date de publication:
25 Oct 2023
25 Oct 2023
Historique:
medline:
26
10
2023
pubmed:
5
10
2023
entrez:
5
10
2023
Statut:
ppublish
Résumé
Molecular changes in malignant tissue can lead to an increase in the expression levels of various proteins or receptors that can be used to target the disease. In oncology, diagnostic imaging and radiotherapy of tumors is possible by attaching an appropriate radionuclide to molecules that selectively bind to these target proteins. The term "theranostics" describes the use of a diagnostic tool to predict the efficacy of a therapeutic option. Molecules radiolabeled with γ-emitting or β
Identifiants
pubmed: 37796539
doi: 10.1021/acs.chemrev.3c00456
doi:
Substances chimiques
Lutetium-177
BRH40Y9V1Q
Copper-67
0
Copper Radioisotopes
0
Gallium-68
98B30EPP5S
Lead-212
0
Actinium-225
0
Lead Radioisotopes
0
Lutetium
5H0DOZ21UJ
Radiopharmaceuticals
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM