Influence of different heat stress models on nutrient digestibility and markers of stress, inflammation, lipid, and protein metabolism in broilers.
digestibility
gene expression
heat stress
inflammation
metabolism
Journal
Poultry science
ISSN: 1525-3171
Titre abrégé: Poult Sci
Pays: England
ID NLM: 0401150
Informations de publication
Date de publication:
Nov 2023
Nov 2023
Historique:
received:
16
05
2023
revised:
03
08
2023
accepted:
16
08
2023
medline:
2
11
2023
pubmed:
5
10
2023
entrez:
5
10
2023
Statut:
ppublish
Résumé
This experiment determined the effects of different HS models and pair-feeding (PF) on nutrient digestibility and markers of stress, inflammation, and metabolism in broilers. Birds (720 total) were allocated into 12 environmentally controlled chambers and reared under thermoneutral conditions until 20 d. Until 41 d birds were exposed to 4 treatments, including: thermoneutral at 24°C (TN-al), daily cyclic HS (12 h at 24 and 12 h at 35°C; cyHS), constant HS at 35°C (coHS), and PF birds maintained at 24°C and fed to equalize FI with coHS birds (TN-coPF). At d 41, ileal digesta were collected to determine nutrient apparent ileal digestibility (AID). Blood, liver, and breast tissues were collected from 8 birds per treatment to determine the mRNA expression of stress, inflammation, and metabolism markers. An additional 8 TN-al birds were sampled after acute HS exposure at 35°C for 4 h (aHS), and 8 cyHS birds were sampled either right before or 4 h after HS initiation. Data were analyzed by 1-way ANOVA and means were separated using Tukey's HSD test. Compared with TN-al birds, AID of nitrogen and ether extract were reduced in coHS birds, and both cyHS and coHS reduced (P < 0.05) AID of total essential amino acids. TNFα and SOD2 expression were increased (P < 0.05) under aHS, coHS, and TN-coPF conditions. IL6 and HSP70 were increased (P < 0.05) under coHS and aHS, respectively. Expression of lipogenic enzymes ACCα and FASN were reduced by coHS and TN-coPF, while coHS increased the lipolytic enzyme ATGL (P < 0.05). IGF1 was lowered in coHS birds, and p70S6K and MyoG were reduced under coHS and TN-coPF (P < 0.05). Interestingly, MuRF1 and MAFbx were increased (P < 0.05) under coHS only. Overall, these results indicate that coHS has a greater impact on nutrient digestibility and metabolism than aHS and cyHS. Interestingly, increased protein degradation during HS appears to be mostly driven by HS per se and not the reduced FI.
Identifiants
pubmed: 37797358
pii: S0032-5791(23)00567-9
doi: 10.1016/j.psj.2023.103048
pmc: PMC10613759
pii:
doi:
Substances chimiques
Lipids
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
103048Informations de copyright
Copyright © 2023 The Authors. Published by Elsevier Inc. All rights reserved.
Références
Cell Stress Chaperones. 2021 May;26(3):563-574
pubmed: 33743152
Front Physiol. 2022 Aug 08;13:943612
pubmed: 36003648
J Therm Biol. 2017 Dec;70(Pt B):9-14
pubmed: 29108563
Front Physiol. 2022 Aug 04;13:934381
pubmed: 35991182
Res Vet Sci. 2019 Feb;122:193-199
pubmed: 30550926
Comp Biochem Physiol. 1968 Jul;26(1):111-20
pubmed: 5758294
Poult Sci. 2011 Oct;90(10):2311-20
pubmed: 21934015
Adv Exp Med Biol. 2017;1000:187-210
pubmed: 29098623
Poult Sci. 2018 Sep 1;97(9):3358-3368
pubmed: 30137545
J Therm Biol. 2017 Oct;69:184-190
pubmed: 29037381
Poult Sci. 2021 Mar;100(3):100801
pubmed: 33518325
Poult Sci. 2017 Dec 1;96(12):4325-4332
pubmed: 29053872
PLoS One. 2017 Jul 31;12(7):e0181900
pubmed: 28759571
Ann Allergy Asthma Immunol. 2008 Apr;100(4):333-7
pubmed: 18450118
J Physiol Pharmacol. 2005 Jun;56 Suppl 3:25-35
pubmed: 16077194
Poult Sci. 1993 Feb;72(2):289-95
pubmed: 8441731
Trends Endocrinol Metab. 2009 Sep;20(7):349-56
pubmed: 19729319
Curr Med Chem. 2012;19(28):4850-60
pubmed: 22709007
Eur J Appl Physiol. 2008 Feb;102(3):253-63
pubmed: 17940791
Free Radic Biol Med. 2006 Sep 1;41(5):709-21
pubmed: 16895791
Comp Biochem Physiol. 1969 Jan;28(1):431-5
pubmed: 5777391
Am J Physiol. 1967 Jul;213(1):245-9
pubmed: 6027925
J Nutr. 2000 Apr;130(4):813-9
pubmed: 10736335
Int J Biometeorol. 2019 Dec;63(12):1569-1584
pubmed: 31352522
Front Vet Sci. 2021 Jul 23;8:699081
pubmed: 34368284
Poult Sci. 2019 Feb 1;98(2):878-886
pubmed: 30239846
J Agric Food Chem. 2017 Dec 27;65(51):11251-11258
pubmed: 29212325
Int J Biometeorol. 2017 Dec;61(12):2111-2118
pubmed: 28799035
Animals (Basel). 2020 Dec 16;10(12):
pubmed: 33339245
PLoS One. 2014 Jul 29;9(7):e102204
pubmed: 25072282
Domest Anim Endocrinol. 2021 Jan;74:106487
pubmed: 32861191
Semin Cell Dev Biol. 2017 Dec;72:10-18
pubmed: 29127045
Comp Biochem Physiol A Mol Integr Physiol. 2006 May;144(1):11-7
pubmed: 16517194
Poult Sci. 2018 Dec 1;97(12):4150-4158
pubmed: 29982693
J Sci Food Agric. 2015 Jan;95(2):429-36
pubmed: 24871527
Nat Protoc. 2008;3(6):1101-8
pubmed: 18546601
Mol Cell. 2004 May 7;14(3):395-403
pubmed: 15125842
Poult Sci. 2022 Aug;101(8):101963
pubmed: 35709683
Antioxidants (Basel). 2020 Dec 30;10(1):
pubmed: 33396952
Poult Sci. 2019 Sep 1;98(9):3695-3704
pubmed: 30809677
Animals (Basel). 2013 Apr 24;3(2):356-69
pubmed: 26487407
J Appl Physiol (1985). 2007 Jul;103(1):378-87
pubmed: 17332274
PLoS One. 2015 Sep 24;10(9):e0138975
pubmed: 26402906
J Anim Sci Biotechnol. 2022 Jul 18;13(1):79
pubmed: 35843965
Meta Gene. 2015 Aug 31;6:17-25
pubmed: 26380816
Biol Trace Elem Res. 2012 Sep;148(3):322-30
pubmed: 22426748
Poult Sci. 2012 Nov;91(11):2931-7
pubmed: 23091152
Antioxidants (Basel). 2019 Jul 22;8(7):
pubmed: 31336672
Cell Stress Chaperones. 2007 Autumn;12(3):245-54
pubmed: 17915557
Br Poult Sci. 1984 Jul;25(3):401-7
pubmed: 6478282
Front Physiol. 2017 Nov 27;8:919
pubmed: 29230177
Poult Sci. 2017 Jul 1;96(7):2312-2319
pubmed: 28339933
Poult Sci. 2018 Feb 1;97(2):430-437
pubmed: 29077887
Poult Sci. 1997 Jun;76(6):857-63
pubmed: 9181619
Poult Sci. 2019 Dec 1;98(12):6378-6387
pubmed: 31406997
J Anim Sci. 2015 May;93(5):2144-53
pubmed: 26020310
Poult Sci. 2021 Jan;100(1):215-223
pubmed: 33357684
Br J Nutr. 1996 Feb;75(2):195-204
pubmed: 8785198
Front Physiol. 2021 Jul 22;12:707757
pubmed: 34366895
Viruses. 2021 Jul 29;13(8):
pubmed: 34452353
J Sci Food Agric. 2019 Oct;99(13):5631-5637
pubmed: 31106428
Br Poult Sci. 1996 May;37(2):443-9
pubmed: 8773853
Poult Sci. 2010 Jan;89(1):115-22
pubmed: 20008809
Int J Biometeorol. 2015 Feb;59(2):127-35
pubmed: 24736810
Animals (Basel). 2021 Jun 30;11(7):
pubmed: 34208851
Poult Sci. 2012 Apr;91(4):781-9
pubmed: 22399715
Poult Sci. 2014 Jan;93(1):54-62
pubmed: 24570423
Poult Sci. 2019 Sep 1;98(9):4113-4122
pubmed: 31065718
Comp Biochem Physiol A Mol Integr Physiol. 2010 Nov;157(3):266-71
pubmed: 20656050
Front Genet. 2017 Dec 05;8:192
pubmed: 29259622
Nature. 2011 May 19;473(7347):337-42
pubmed: 21593866
J Anim Sci Biotechnol. 2016 Jun 28;7:37
pubmed: 27354915
Animals (Basel). 2021 May 20;11(5):
pubmed: 34065334
Comp Biochem Physiol C Toxicol Pharmacol. 2010 Mar;151(2):204-8
pubmed: 19883793
Animal. 2016 Jan;10(1):163-71
pubmed: 26677935
J Therm Biol. 2018 May;74:337-343
pubmed: 29801647
J Sci Food Agric. 2023 Mar 30;103(5):2367-2377
pubmed: 36606563
Science. 2004 Nov 19;306(5700):1383-6
pubmed: 15550674
J Sci Food Agric. 2021 Mar 30;101(5):2125-2134
pubmed: 32978773
Domest Anim Endocrinol. 1997 Jul;14(4):199-229
pubmed: 9260060
J Anim Sci. 2020 Mar 1;98(3):
pubmed: 32047923
Am J Physiol Endocrinol Metab. 2004 Oct;287(4):E591-601
pubmed: 15100091
Comp Biochem Physiol A Mol Integr Physiol. 2010 Mar;155(3):401-6
pubmed: 20036750
J Nutr. 1999 Jan;129(1S Suppl):227S-237S
pubmed: 9915905
Growth Horm IGF Res. 2003 Feb;13(1):8-18
pubmed: 12550077
Poult Sci. 1999 Oct;78(10):1341-6
pubmed: 10536779
PLoS One. 2017 Oct 11;12(10):e0186083
pubmed: 29020081