Chemokine Receptor PET/CT Provides Relevant Staging and Management Changes in Marginal Zone Lymphoma.

Humans Positron Emission Tomography Computed Tomography / methods Retrospective Studies Lymphoma, B-Cell, Marginal Zone / pathology Prognosis Proportional Hazards Models Fluorodeoxyglucose F18 Neoplasm Staging
CXCR4 PET/CT marginal zone lymphoma mucosa-associated lymphoid tissue lymphoma theranostics

Journal

Journal of nuclear medicine : official publication, Society of Nuclear Medicine
ISSN: 1535-5667
Titre abrégé: J Nucl Med
Pays: United States
ID NLM: 0217410

Informations de publication

Date de publication:
01 Dec 2023
Historique:
received: 25 05 2023
revised: 07 09 2023
medline: 4 12 2023
pubmed: 6 10 2023
entrez: 5 10 2023
Statut: epublish

Résumé

Because of gastral and extranodal manifestations, guideline-compatible diagnostic work-up of marginal zone lymphoma is challenging. We aimed to determine the diagnostic performance of C-X-C motif chemokine receptor 4 (CXCR4)-directed PET/CT compared with routine diagnostics, along with PET/CT-based retrospective changes in therapeutic management. The predictive potential of the PET signal was also investigated, and the number of patients eligible for CXCR4-directed radioligand therapy in a theranostic setting was determined.

Identifiants

DOI: 10.2967/jnumed.123.266074 PMID: 37797975
pubmed: 37797975
pii: jnumed.123.266074
doi: 10.2967/jnumed.123.266074
doi:

Substances chimiques

Fluorodeoxyglucose F18 0Z5B2CJX4D

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1889-1894

Informations de copyright

© 2023 by the Society of Nuclear Medicine and Molecular Imaging.

Auteurs

Johannes Duell (J)

Medical Department II, University Hospital Würzburg, Würzburg, Germany.

Andreas K Buck (AK)

Department of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany.

Philipp E Hartrampf (PE)

Department of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany.

Wiebke Schlötelburg (W)

Department of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany.

Simone Schneid (S)

Department of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany.

Alexander Weich (A)

Medical Department II, University Hospital Würzburg, Würzburg, Germany.

Niklas Dreher (N)

Department of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany.

Constantin Lapa (C)

Nuclear Medicine, Faculty of Medicine, University of Augsburg, Augsburg, Germany.

Malte Kircher (M)

Nuclear Medicine, Faculty of Medicine, University of Augsburg, Augsburg, Germany.

Takahiro Higuchi (T)

Department of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany.

Samuel Samnick (S)

Department of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany.

Sebastian E Serfling (SE)

Department of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany.

Markus Raderer (M)

Department of Internal Medicine I, Medical University Vienna, Vienna, Austria.

Leo Rasche (L)

Medical Department II, University Hospital Würzburg, Würzburg, Germany.
Comprehensive Cancer Center Mainfranken, University Hospital Würzburg, Würzburg, Germany; and.

Hermann Einsele (H)

Medical Department II, University Hospital Würzburg, Würzburg, Germany.
Comprehensive Cancer Center Mainfranken, University Hospital Würzburg, Würzburg, Germany; and.

Max S Topp (MS)

Medical Department II, University Hospital Würzburg, Würzburg, Germany.
Comprehensive Cancer Center Mainfranken, University Hospital Würzburg, Würzburg, Germany; and.

Aleksander Kosmala (A)

Department of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany; kosmala_a@ukw.de.

Rudolf A Werner (RA)

Department of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany.
Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins School of Medicine, Baltimore, Maryland.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Chemokine Receptor PET/CT Provides Relevant...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Techniques de diagnostic radioisotopique › Scintigraphie › Tomoscintigraphie › Tomographie par émission de positons › Tomographie par émission de positons couplée à la tomodensitométrie › Chemokine Receptor PET/CT Provides Relevant...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études de cohortes › Études rétrospectives › Chemokine Receptor PET/CT Provides Relevant...
questionsmedicales.fr › Maladies du système immunitaire › Syndromes immunoprolifératifs › Syndromes lymphoprolifératifs › Lymphomes › Lymphome malin non hodgkinien › Lymphome B › Lymphome B de la zone marginale › Chemokine Receptor PET/CT Provides Relevant...
questionsmedicales.fr › Diagnostic › Pronostic › Chemokine Receptor PET/CT Provides Relevant...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Statistiques comme sujet › Analyse de survie › Modèles des risques proportionnels › Chemokine Receptor PET/CT Provides Relevant...
questionsmedicales.fr › Glucides › Désoses › Désoxyglucose › Fluorodésoxyglucose F18 › Chemokine Receptor PET/CT Provides Relevant...
questionsmedicales.fr › Diagnostic › Pronostic › Stadification tumorale › Chemokine Receptor PET/CT Provides Relevant...