Uncoupling of the center-to-periphery arterial stiffness gradient and pulse pressure amplification in viral pneumonia infection.
Aortic stiffness
Arterial stiffness gradient
Blood pressure
Hemodynamics
Journal
BMC infectious diseases
ISSN: 1471-2334
Titre abrégé: BMC Infect Dis
Pays: England
ID NLM: 100968551
Informations de publication
Date de publication:
05 Oct 2023
05 Oct 2023
Historique:
received:
15
05
2023
accepted:
26
09
2023
medline:
1
11
2023
pubmed:
6
10
2023
entrez:
5
10
2023
Statut:
epublish
Résumé
Arterial stiffness is a common manifestation of viral pneumonia infections, including COVID-19. Nevertheless, the relationship between the center-to-periphery arterial stiffness gradient and pulse pressure amplification (PPA) in infectious diseases remains unclear. This study aimed to investigate this relationship utilizing arterial pressure volume index (API) and arterial velocity pulse index (AVI) ratio. API/AVI and PPA were measured in 219 participants with COVID-19 and 374 normal participants. Multiple linear regression was used to assess the association of API/AVI and PPA, and restricted cubic spline was used to investigate the non-linear relationship between API/AVI and PPA. Receiver operating characteristic curve (ROC) analysis was used to evaluate the effects of API/AVI in identifying COVID-19 infection and severe stage. There was a significant J-shaped relationship between API/AVI and PPA in COVID-19 group, while a M-shaped relationship was observed in normal group. API/AVI decreased rapidly as PPA decreased until API/AVI decreased slowly at PPA of 1.07, and then API/AVI decreased slowly again at PPA of 0.78. ROC results showed that API/AVI demonstrated excellent accuracy in identifying COVID-19 infection (AUC = 0.781) and a high specificity (84.88%) in identifying severe stage. There was a J-shaped association between the API/AVI and PPA in viral infected patients, while a M-shaped relationship in the normal participants. API/AVI is better for identifying infected and uninfected patients, with a high specificity in identifying those in severe stages of the disease. The attenuation or reversal of API/AVI may be associated with the loss of PPA coupling.
Identifiants
pubmed: 37798630
doi: 10.1186/s12879-023-08650-w
pii: 10.1186/s12879-023-08650-w
pmc: PMC10552441
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
657Subventions
Organisme : Natural Science Foundation of Shanghai
ID : 21ZR1451400
Organisme : Shanghai Health and Family Planning Commission Fund
ID : 202240235
Organisme : Shanghai Jiading District Health and Family Planning Commission Fund
ID : 2021-KY-10
Informations de copyright
© 2023. BioMed Central Ltd., part of Springer Nature.
Références
European Society of Cardiology guidance for the. Diagnosis and management of cardiovascular disease during the COVID-19 pandemic: part 1-epidemiology, pathophysiology, and diagnosis. Eur Heart J. 2022;43(11):1033–58.
doi: 10.1093/eurheartj/ehab696
Olsen FJ, Lassen MCH, Skaarup KG, Christensen J, Davidovski FS, Alhakak AS, Sengeløv M, Nielsen AB, Johansen ND, Graff C, et al. Myocardial work in patients hospitalized with COVID-19: relation to biomarkers, COVID-19 severity, and all-cause mortality. J Am Heart Assoc. 2022;11(19):e026571.
doi: 10.1161/JAHA.122.026571
pubmed: 36129046
pmcid: 9673715
Schnaubelt S, Oppenauer J, Tihanyi D, Mueller M, Maldonado-Gonzalez E, Zejnilovic S, Haslacher H, Perkmann T, Strassl R, Anders S, et al. Arterial stiffness in acute COVID-19 and potential associations with clinical outcome. J Intern Med. 2021;290(2):437–43.
doi: 10.1111/joim.13275
pubmed: 33651387
pmcid: 8013324
Szeghy RE, Province VM, Stute NL, Augenreich MA, Koontz LK, Stickford JL, Stickford ASL, Ratchford SM. Carotid stiffness, intima-media thickness and aortic augmentation index among adults with SARS-CoV-2. Exp Physiol. 2022;107(7):694–707.
doi: 10.1113/EP089481
pubmed: 33904234
Lambadiari V, Mitrakou A, Kountouri A, Thymis J, Katogiannis K, Korakas E, Varlamos C, Andreadou I, Tsoumani M, Triantafyllidi H, et al. Association of COVID-19 with impaired endothelial glycocalyx, vascular function and myocardial deformation 4 months after infection. Eur J Heart Fail. 2021;23(11):1916–26.
doi: 10.1002/ejhf.2326
pubmed: 34415085
Fortier C, Mac-Way F, Desmeules S, Marquis K, De Serres SA, Lebel M, Boutouyrie P, Agharazii M. Aortic-brachial stiffness mismatch and mortality in dialysis population. Hypertension. 2015;65(2):378–84.
doi: 10.1161/HYPERTENSIONAHA.114.04587
pubmed: 25452473
Covic A, Siriopol D. Pulse wave velocity ratio: the new gold standard for measuring arterial stiffness. Hypertension. 2015;65(2):289–90.
doi: 10.1161/HYPERTENSIONAHA.114.04678
pubmed: 25452468
London GM, Pannier B, Safar ME. Arterial stiffness gradient, systemic reflection coefficient, and pulsatile pressure Wave Transmission in essential hypertension. Hypertension. 2019;74(6):1366–72.
doi: 10.1161/HYPERTENSIONAHA.119.13387
pubmed: 31679422
Jin L, Tong L, Shen C, Du L, Mao J, Liu L, Li Z. Association of Arterial Stiffness Indices with Framingham Cardiovascular Disease Risk Score. RCM 2022, 23(8):287.
Ueda T, Miura S, Suematsu Y, Shiga Y, Kuwano T, Sugihara M, Ike A, Iwata A, Nishikawa H, Fujimi K, et al. Association of arterial pressure volume Index with the Presence of significantly stenosed coronary vessels. J Clin Med Res. 2016;8(8):598–604.
doi: 10.14740/jocmr2615w
pubmed: 27429681
pmcid: 4931806
Okamoto M, Nakamura F, Musha T, Kobayashi Y. Association between novel arterial stiffness indices and risk factors of cardiovascular disease. BMC Cardiovasc Disord. 2016;16(1):211.
doi: 10.1186/s12872-016-0389-x
pubmed: 27821070
pmcid: 5100265
Nilsson PM, Cederholm J, Eeg-Olofsson K, Eliasson B, Zethelius B, Gudbjörnsdóttir S. Pulse pressure strongly predicts cardiovascular disease risk in patients with type 2 diabetes from the Swedish National Diabetes Register (NDR). Diabetes Metab. 2009;35(6):439–46.
doi: 10.1016/j.diabet.2009.04.010
pubmed: 19819740
Chirinos JA, Segers P, Gillebert TC, De Buyzere ML, Van Daele CM, Khan ZA, Khawar U, De Bacquer D, Rietzschel ER. Central pulse pressure and its hemodynamic determinants in middle-aged adults with impaired fasting glucose and diabetes: the Asklepios study. Diabetes Care. 2013;36(8):2359–65.
doi: 10.2337/dc12-1463
pubmed: 23610081
pmcid: 3714490
Avolio AP, Van Bortel LM, Boutouyrie P, Cockcroft JR, McEniery CM, Protogerou AD, Roman MJ, Safar ME, Segers P, Smulyan H. Role of pulse pressure amplification in arterial hypertension: experts’ opinion and review of the data. Hypertension. 2009;54(2):375–83.
doi: 10.1161/HYPERTENSIONAHA.109.134379
pubmed: 19564542
Benetos A, Thomas F, Joly L, Blacher J, Pannier B, Labat C, Salvi P, Smulyan H, Safar ME. Pulse pressure amplification a mechanical biomarker of cardiovascular risk. J Am Coll Cardiol. 2010;55(10):1032–7.
doi: 10.1016/j.jacc.2009.09.061
pubmed: 20202520
Kanazawa M, Fukuyama H, Kinefuchi Y, Takiguchi M, Suzuki T. Relationship between aortic-to-radial arterial pressure gradient after cardiopulmonary bypass and changes in arterial elasticity. Anesthesiology. 2003;99(1):48–53.
doi: 10.1097/00000542-200307000-00011
pubmed: 12826841
Saeed S, Mancia G. Arterial stiffness and COVID-19: a bidirectional cause-effect relationship. J Clin Hypertens (Greenwich). 2021;23(6):1099–103.
doi: 10.1111/jch.14259
pubmed: 33951308
Commission NH. Diagnosis and treatment protocol for novel coronavirus pneumonia (trial 10th version). Chin J Clin Infect Dis. 2023;16(1):1–9.
Faqin Lv J, Wang X, Yu A, Yang J-B, Liu L, Qian H, Xu L, Cui M, Xie X, Liu, et al. Chinese Expert Consensus on critical care Ultrasound Applications at COVID-19 pandemic. Adv Ultrasound Diagnosis Therapy. 2020;4(2):27–42.
doi: 10.37015/AUDT.2020.200029
Sasaki-Nakashima R, Kino T, Chen L, Doi H, Minegishi S, Abe K, Sugano T, Taguri M, Ishigami T. Successful prediction of cardiovascular risk by new non-invasive vascular indexes using suprasystolic cuff oscillometric waveform analysis. J Cardiol. 2017;69(1):30–7.
doi: 10.1016/j.jjcc.2016.06.004
pubmed: 27590415
Jin L, Chen J, Zhang M, Sha L, Cao M, Tong L, Chen Q, Shen C, Du L, Li Z et al. Relationship of arterial stiffness and central hemodynamics with cardiovascular risk in hypertension. Am J Hypertens 2023.
Hashimoto J, Ito S. Aortic stiffness determines diastolic blood flow reversal in the descending thoracic aorta: potential implication for retrograde embolic stroke in hypertension. Hypertension. 2013;62(3):542–9.
doi: 10.1161/HYPERTENSIONAHA.113.01318
pubmed: 23798349
Nägele MP, Haubner B, Tanner FC, Ruschitzka F, Flammer AJ. Endothelial dysfunction in COVID-19: current findings and therapeutic implications. Atherosclerosis. 2020;314:58–62.
doi: 10.1016/j.atherosclerosis.2020.10.014
pubmed: 33161318
pmcid: 7554490
Kaur S, Tripathi DM, Yadav A. The Enigma of Endothelium in COVID-19. Front Physiol. 2020;11:989.
doi: 10.3389/fphys.2020.00989
pubmed: 32848893
pmcid: 7417426
Varga Z, Flammer AJ, Steiger P, Haberecker M, Andermatt R, Zinkernagel AS, Mehra MR, Schuepbach RA, Ruschitzka F, Moch H. Endothelial cell infection and endotheliitis in COVID-19. Lancet. 2020;395(10234):1417–8.
doi: 10.1016/S0140-6736(20)30937-5
pubmed: 32325026
pmcid: 7172722
Bonetti PO, Lerman LO, Lerman A. Endothelial dysfunction: a marker of atherosclerotic risk. Arterioscler Thromb Vasc Biol. 2003;23(2):168–75.
doi: 10.1161/01.ATV.0000051384.43104.FC
pubmed: 12588755
Tomiyama H, Shiina K. State of the art review: brachial-ankle PWV. J Atheroscler Thromb. 2020;27(7):621–36.
doi: 10.5551/jat.RV17041
pubmed: 32448827
pmcid: 7406407
Vlachopoulos C, Xaplanteris P, Aboyans V, Brodmann M, Cífková R, Cosentino F, De Carlo M, Gallino A, Landmesser U, Laurent S, et al. The role of vascular biomarkers for primary and secondary prevention. A position paper from the European Society of Cardiology Working Group on peripheral circulation: endorsed by the Association for Research into arterial structure and physiology (ARTERY) society. Atherosclerosis. 2015;241(2):507–32.
doi: 10.1016/j.atherosclerosis.2015.05.007
pubmed: 26117398
Wang B, Zhang L, Zhang D, Yuan H, Wu C, Zhang Y, He L, Wang R, Wang J. Mingxing Xie: Bedside Ultrasound in Assessment of 510 severe and critical patients with COVID-19 pneumonia in Wuhan, China. Adv Ultrasound Diagnosis Therapy. 2020;4(2):60–6.
doi: 10.37015/AUDT.2020.200018
Zanoli L, Briet M, Empana JP, Cunha PG, Mäki-Petäjä KM, Protogerou AD, Tedgui A, Touyz RM, Schiffrin EL, Spronck B, et al. Vascular consequences of inflammation: a position statement from the ESH Working Group on Vascular structure and function and the ARTERY Society. J Hypertens. 2020;38(9):1682–98.
doi: 10.1097/HJH.0000000000002508
pubmed: 32649623
pmcid: 7610698
Zanoli L, Boutouyrie P, Fatuzzo P, Granata A, Lentini P, Oztürk K, Cappello M, Theocharidou E, Tuttolomondo A, Pinto A et al. Inflammation and aortic stiffness: an individual Participant Data Meta-Analysis in patients with inflammatory bowel disease. J Am Heart Assoc 2017, 6(10).
Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, Wang B, Xiang H, Cheng Z, Xiong Y, et al. Clinical characteristics of 138 hospitalized patients with 2019 Novel Coronavirus-Infected pneumonia in Wuhan, China. JAMA. 2020;323(11):1061–9.
doi: 10.1001/jama.2020.1585
pubmed: 32031570
pmcid: 7042881
Russell G, Lightman S. The human stress response. Nat Rev Endocrinol. 2019;15(9):525–34.
doi: 10.1038/s41574-019-0228-0
pubmed: 31249398
Cianfarani S, Pampanini V. The impact of stress on Health in Childhood and Adolescence in the era of the COVID-19 pandemic. Horm Res Paediatr. 2023;96(1):83–7.
doi: 10.1159/000517460
pubmed: 34261075
Zhou X, Lu H, Sang M, Qiu S, Yuan Y, Wu T, Chen J, Sun Z. Impaired antibody response to inactivated COVID-19 vaccines in hospitalized patients with type 2 diabetes. Hum Vaccin Immunother. 2023;19(1):2184754.
doi: 10.1080/21645515.2023.2184754
pubmed: 36864628
pmcid: 10026888