Distinct and targetable role of calcium-sensing receptor in leukaemia.


Journal

Nature communications
ISSN: 2041-1723
Titre abrégé: Nat Commun
Pays: England
ID NLM: 101528555

Informations de publication

Date de publication:
06 10 2023
Historique:
received: 30 09 2022
accepted: 12 09 2023
medline: 2 11 2023
pubmed: 7 10 2023
entrez: 6 10 2023
Statut: epublish

Résumé

Haematopoietic stem cells (HSC) reside in the bone marrow microenvironment (BMM), where they respond to extracellular calcium [eCa

Identifiants

pubmed: 37802982
doi: 10.1038/s41467-023-41770-0
pii: 10.1038/s41467-023-41770-0
pmc: PMC10558580
doi:

Substances chimiques

Receptors, Calcium-Sensing 0
Proto-Oncogene Proteins c-myc 0
Calcium SY7Q814VUP
Oncogene Proteins, Fusion 0
Cytarabine 04079A1RDZ

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

6242

Informations de copyright

© 2023. Springer Nature Limited.

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Auteurs

Raquel S Pereira (RS)

Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt am Main, Germany.

Rahul Kumar (R)

Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt am Main, Germany.

Alessia Cais (A)

Pediatric Neurooncology, Hopp Children's Cancer Center Heidelberg (KiTZ) and German Cancer Research Center (DKFZ), Heidelberg, Germany.

Lara Paulini (L)

Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt am Main, Germany.

Alisa Kahler (A)

Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt am Main, Germany.

Jimena Bravo (J)

Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt am Main, Germany.

Valentina R Minciacchi (VR)

Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt am Main, Germany.

Theresa Krack (T)

Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt am Main, Germany.

Eric Kowarz (E)

Institute of Pharmaceutical Biology, Goethe University, Frankfurt am Main, Germany.

Costanza Zanetti (C)

University Medical Center, Johannes Gutenberg University Mainz, Mainz, Germany.

Parimala Sonika Godavarthy (PS)

Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt am Main, Germany.

Fabian Hoeller (F)

Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt am Main, Germany.

Pablo Llavona (P)

Institute of Molecular Biology gGmbH (IMB), Mainz, Germany.

Tabea Stark (T)

Institute of Biochemistry II, Faculty of Medicine, Goethe University, Frankfurt am Main, Germany.

Georg Tascher (G)

Institute of Biochemistry II, Faculty of Medicine, Goethe University, Frankfurt am Main, Germany.

Daniel Nowak (D)

Department of Hematology and Oncology, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.

Eshwar Meduri (E)

Department of Haematology, University of Cambridge, Cambridge, United Kingdom.

Brian J P Huntly (BJP)

Department of Haematology, University of Cambridge, Cambridge, United Kingdom.

Christian Münch (C)

Institute of Biochemistry II, Faculty of Medicine, Goethe University, Frankfurt am Main, Germany.

Francesco Pampaloni (F)

Buchmann Institute for Molecular Life Sciences (BMLS, CEF-MC), Goethe University, Frankfurt am Main, Germany.

Rolf Marschalek (R)

Institute of Pharmaceutical Biology, Goethe University, Frankfurt am Main, Germany.

Daniela S Krause (DS)

Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt am Main, Germany. Krause@gsh.uni-frankfurt.de.
Institute of Biochemistry II, Faculty of Medicine, Goethe University, Frankfurt am Main, Germany. Krause@gsh.uni-frankfurt.de.
Institute of General Pharmacology and Toxicology, Goethe-University, Frankfurt am Main, Germany. Krause@gsh.uni-frankfurt.de.
German Cancer Research Center (DKFZ), Heidelberg, Germany. Krause@gsh.uni-frankfurt.de.
German Cancer Consortium (DKTK), Heidelberg, Germany. Krause@gsh.uni-frankfurt.de.
Frankfurt Cancer Institute, Frankfurt, Germany. Krause@gsh.uni-frankfurt.de.

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