Genetic insights into crossbred dairy cattle of Pakistan: exploring allele frequency, linkage disequilibrium, and effective population size at a genome-wide scale.


Journal

Mammalian genome : official journal of the International Mammalian Genome Society
ISSN: 1432-1777
Titre abrégé: Mamm Genome
Pays: United States
ID NLM: 9100916

Informations de publication

Date de publication:
12 2023
Historique:
received: 27 06 2023
accepted: 13 09 2023
medline: 7 11 2023
pubmed: 7 10 2023
entrez: 7 10 2023
Statut: ppublish

Résumé

Linkage disequilibrium (LD) affects genomic studies accuracy. High-density genotyping platforms identify SNPs across animal genomes, increasing LD evaluation resolution for accurate analysis. This study aimed to evaluate the decay and magnitude of LD in a cohort of 81 crossbred dairy cattle using the GGP_HDv3_C Bead Chip. After quality control, 116,710 Single Nucleotide Polymorphisms (SNPs) across 2520.241 Mb of autosomes were retained. LD extent was assessed between autosomal SNPs within a 10 Mb range using the r

Identifiants

pubmed: 37804434
doi: 10.1007/s00335-023-10019-y
pii: 10.1007/s00335-023-10019-y
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

602-614

Informations de copyright

© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

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Auteurs

Fakhar Un Nisa (FU)

Agricultural Biotechnology Division, National Institute for Biotechnology and Genetic Engineering College (NIBGE-C), Faisalabad, Pakistan.
Pakistan Institute of Engineering and Applied Sciences (PIEAS), Nilore, Islamabad, Pakistan.
Department of Animal Breeding and Genetics, University of Veterinary and Animal Sciences, Lahore, Pakistan.

Haiba Kaul (H)

Department of Animal Breeding and Genetics, University of Veterinary and Animal Sciences, Lahore, Pakistan.

Muhammad Asif (M)

Agricultural Biotechnology Division, National Institute for Biotechnology and Genetic Engineering College (NIBGE-C), Faisalabad, Pakistan.
Pakistan Institute of Engineering and Applied Sciences (PIEAS), Nilore, Islamabad, Pakistan.

Imran Amin (I)

Agricultural Biotechnology Division, National Institute for Biotechnology and Genetic Engineering College (NIBGE-C), Faisalabad, Pakistan.
Pakistan Institute of Engineering and Applied Sciences (PIEAS), Nilore, Islamabad, Pakistan.

Raphael Mrode (R)

Animal Biosciences, International Livestock Research Institute, Nairobi, Kenya.
Animal and Veterinary Sciences, Scotland's Rural College, Edinburgh, UK.

Shahid Mansoor (S)

Agricultural Biotechnology Division, National Institute for Biotechnology and Genetic Engineering College (NIBGE-C), Faisalabad, Pakistan.
Pakistan Institute of Engineering and Applied Sciences (PIEAS), Nilore, Islamabad, Pakistan.
International Centre for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan.

Zahid Mukhtar (Z)

Agricultural Biotechnology Division, National Institute for Biotechnology and Genetic Engineering College (NIBGE-C), Faisalabad, Pakistan. zahidmukhtar@yahoo.com.
Pakistan Institute of Engineering and Applied Sciences (PIEAS), Nilore, Islamabad, Pakistan. zahidmukhtar@yahoo.com.

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