Rapid multi-residue LC-MS/MS determination of nitrofuran metabolites, nitroimidazoles, amphenicols, and quinolones in honey with ultrasonic-assisted derivatization - magnetic solid-phase extraction.
Chromatography, Liquid
/ methods
Chloramphenicol
/ analysis
Nitroimidazoles
/ analysis
Quinolones
/ analysis
Honey
/ analysis
Veterinary Drugs
/ analysis
Ultrasonics
Tandem Mass Spectrometry
/ methods
Anti-Bacterial Agents
/ analysis
Nitrofurans
/ analysis
Solid Phase Extraction
/ methods
Magnetic Phenomena
Chromatography, High Pressure Liquid
/ methods
Honey
LC-MS/MS
Magnetic solid-phase extraction
Multiresidue analysis
Veterinary drugs
Journal
Journal of pharmaceutical and biomedical analysis
ISSN: 1873-264X
Titre abrégé: J Pharm Biomed Anal
Pays: England
ID NLM: 8309336
Informations de publication
Date de publication:
05 Jan 2024
05 Jan 2024
Historique:
received:
09
07
2023
revised:
05
09
2023
accepted:
02
10
2023
medline:
3
11
2023
pubmed:
8
10
2023
entrez:
7
10
2023
Statut:
ppublish
Résumé
A rapid multi-residue LC-MS/MS method for the identification and determination of banned veterinary drugs in honey was developed. A total of 31 investigated veterinary drugs belonging to 4 classes including nitrofurans metabolites, nitroimidazoles, amphenicols, and quinolones were quantified by LC-MS/MS with ESI using one single injection. The sample preparation included treatment with 5-nitro-2-furaldehyde (5-NFA) in a thermostated ultrasonic bath (80 °C, 0.5М НСl, 20 min) to liberate matrix-bound residues of nitrofurans. Magnetic hypercrosslinked polystyrene (HCP/Fe
Identifiants
pubmed: 37804641
pii: S0731-7085(23)00533-2
doi: 10.1016/j.jpba.2023.115764
pii:
doi:
Substances chimiques
Chloramphenicol
66974FR9Q1
Nitroimidazoles
0
Quinolones
0
Veterinary Drugs
0
Anti-Bacterial Agents
0
Nitrofurans
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
115764Informations de copyright
Copyright © 2023 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.