Factors associated with short- and long-term outcomes in lung cancer patients requiring unplanned invasive mechanical ventilation.

Cáncer de pulmón Destete ventilatorio Intubación Intubation Long-term prognosis Lung cancer Mechanical ventilation Pronóstico a largo plazo Ventilación mecánica Ventilator weaning

Journal

Medicina intensiva
ISSN: 2173-5727
Titre abrégé: Med Intensiva (Engl Ed)
Pays: Spain
ID NLM: 101717568

Informations de publication

Date de publication:
06 Oct 2023
Historique:
received: 29 03 2023
accepted: 07 07 2023
medline: 9 10 2023
pubmed: 9 10 2023
entrez: 8 10 2023
Statut: aheadofprint

Résumé

Unplanned invasive mechanical ventilation (IMV) is associated with high mortality in lung cancer patients. We aimed to identify factors associated with weaning from IMV, intensive care unit (ICU) survival and 1-year survival in lung cancer patients requiring unplanned IMV. Retrospective observational study (2007-2017). University-affiliated ICU. Lung cancer patients requiring unplanned IMV. None. Weaning from IMV, ICU and 1-year survival. Of the 136 patients included in the analysis (age 64 (9) years, male 110 (81%), metastatic disease 97 (62%)), 52 (38%) were weaned from IMV, 51 (38%) were discharged from ICU and 22 (16%) were alive at 1year. The main indication for intubation was acute respiratory failure. In multivariate analysis, PaO A significant proportion of patients with lung cancer treated with unplanned IMV could be weaned from IMV and survived to ICU discharge, especially in the absence of severe hypoxemia at ICU admission. The low one-year survival was mostly driven by metastatic status.

Identifiants

pubmed: 37806828
pii: S2173-5727(23)00137-6
doi: 10.1016/j.medine.2023.07.014
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2023 Elsevier España, S.L.U. and SEMICYUC. All rights reserved.

Auteurs

Emeric Chatelain (E)

Hospices Civils de Lyon, Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation, F-69437, Lyon, France.

Marie Simon (M)

Hospices Civils de Lyon, Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation, F-69437, Lyon, France.

Romain Hernu (R)

Hospices Civils de Lyon, Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation, F-69437, Lyon, France.

Laurent Argaud (L)

Hospices Civils de Lyon, Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation, F-69437, Lyon, France; Université de Lyon, Université Claude Bernard Lyon 1, Faculté de Médecine Lyon-Est, F-69373, Lyon, France.

Martin Cour (M)

Hospices Civils de Lyon, Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation, F-69437, Lyon, France; Université de Lyon, Université Claude Bernard Lyon 1, Faculté de Médecine Lyon-Est, F-69373, Lyon, France. Electronic address: martin.cour@chu-lyon.fr.

Classifications MeSH