Adaptation and Uncertainty: A Qualitative Examination of Provider Experiences With Prone Positioning for Intubated Patients With COVID-19 ARDS.

COVID-19 acute respiratory distress syndrome implementation science prone position

Journal

CHEST critical care
ISSN: 2949-7884
Titre abrégé: CHEST Crit Care
Pays: United States
ID NLM: 9918681585806676

Informations de publication

Date de publication:
Sep 2023
Historique:
medline: 9 10 2023
pubmed: 9 10 2023
entrez: 9 10 2023
Statut: ppublish

Résumé

Prone positioning was widely adopted for use in patients with ARDS from COVID-19. However, proning was also delivered in ways that differed from historical evidence and practice. In implementation research, these changes are referred to as adaptations, and they occur constantly as evidence-based interventions are used in real-world practice. Adaptations can alter the delivered intervention, impacting patient and implementation outcomes. How have clinicians adapted prone positioning to COVID-19 ARDS, and what uncertainties remain regarding optimal proning use? We conducted a qualitative study using semi-structured interviews with ICU clinicians from two hospitals in Baltimore, MD, from February to July 2021. We interviewed physicians (MDs), registered nurses (RNs), respiratory therapists (RTs), advanced practice providers (APPs), and physical therapists (PTs) involved with proning mechanically ventilated patients with COVID-19 ARDS. We used thematic analysis of interviews to classify proning adaptations and clinician uncertainties about best practice for prone positioning. Forty ICU clinicians (12 MDs, 4 APPs, 12 RNs, 7 RTs, and 5 PTs) were interviewed. Clinicians described several adaptations to the practice of prone positioning, including earlier proning initiation, extended duration of proning sessions, and less use of concomitant neuromuscular blockade. Clinicians expressed uncertainty regarding the optimal timing of initiation and duration of prone positioning. This uncertainty was viewed as a driver of practice variation. Although prescribers intended to use less deep sedation and paralysis in proned patients compared with historical evidence and practice, this raised concerns regarding patient comfort and safety amongst RNs and RTs. Prone positioning in patients with COVID-19 ARDS has been adapted from historically described practice. Understanding the impact of these adaptations on patient and implementation outcomes and addressing clinician uncertainties are priority areas for future research to optimize the use of prone positioning.

Sections du résumé

BACKGROUND BACKGROUND
Prone positioning was widely adopted for use in patients with ARDS from COVID-19. However, proning was also delivered in ways that differed from historical evidence and practice. In implementation research, these changes are referred to as adaptations, and they occur constantly as evidence-based interventions are used in real-world practice. Adaptations can alter the delivered intervention, impacting patient and implementation outcomes.
RESEARCH QUESTION OBJECTIVE
How have clinicians adapted prone positioning to COVID-19 ARDS, and what uncertainties remain regarding optimal proning use?
STUDY DESIGN AND METHODS METHODS
We conducted a qualitative study using semi-structured interviews with ICU clinicians from two hospitals in Baltimore, MD, from February to July 2021. We interviewed physicians (MDs), registered nurses (RNs), respiratory therapists (RTs), advanced practice providers (APPs), and physical therapists (PTs) involved with proning mechanically ventilated patients with COVID-19 ARDS. We used thematic analysis of interviews to classify proning adaptations and clinician uncertainties about best practice for prone positioning.
RESULTS RESULTS
Forty ICU clinicians (12 MDs, 4 APPs, 12 RNs, 7 RTs, and 5 PTs) were interviewed. Clinicians described several adaptations to the practice of prone positioning, including earlier proning initiation, extended duration of proning sessions, and less use of concomitant neuromuscular blockade. Clinicians expressed uncertainty regarding the optimal timing of initiation and duration of prone positioning. This uncertainty was viewed as a driver of practice variation. Although prescribers intended to use less deep sedation and paralysis in proned patients compared with historical evidence and practice, this raised concerns regarding patient comfort and safety amongst RNs and RTs.
INTERPRETATION CONCLUSIONS
Prone positioning in patients with COVID-19 ARDS has been adapted from historically described practice. Understanding the impact of these adaptations on patient and implementation outcomes and addressing clinician uncertainties are priority areas for future research to optimize the use of prone positioning.

Identifiants

pubmed: 37810258
doi: 10.1016/j.chstcc.2023.100008
pmc: PMC10560392
mid: NIHMS1933150
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : NHLBI NIH HHS
ID : F32 HL160039
Pays : United States
Organisme : NHLBI NIH HHS
ID : T32 HL007534
Pays : United States

Références

Am J Respir Crit Care Med. 2021 Jun 1;203(11):1366-1377
pubmed: 33406009
JAMA. 2016 Feb 23;315(8):788-800
pubmed: 26903337
Crit Care Explor. 2022 May 13;4(5):e0695
pubmed: 35783548
Respir Care. 2020 Apr;65(4):413-419
pubmed: 31992664
J Crit Care. 2020 Dec;60:230-234
pubmed: 32916611
Lancet Respir Med. 2021 Feb;9(2):139-148
pubmed: 33169671
Annu Rev Public Health. 2018 Apr 1;39:55-76
pubmed: 29328872
J Crit Care. 2012 Apr;27(2):218.e1-7
pubmed: 22227084
Int J Qual Health Care. 2018 Apr 20;30(suppl_1):20-23
pubmed: 29878138
Am J Crit Care. 2020 May 1;29(3):e52-e59
pubmed: 32355970
Crit Care Med. 2022 Apr 1;50(4):633-643
pubmed: 34582426
J Crit Care. 2015 Aug;30(4):698-704
pubmed: 25837800
N Engl J Med. 2013 Jun 6;368(23):2159-68
pubmed: 23688302
Ann Am Thorac Soc. 2017 Oct;14(Supplement_4):S280-S288
pubmed: 29068269
Chest. 2020 Jun;157(6):1497-1505
pubmed: 32088180
Crit Care. 2022 Mar 24;26(1):71
pubmed: 35331332
J Intensive Care Med. 2022 Jul;37(7):883-889
pubmed: 35195460
Chest. 2021 Oct;160(4):1304-1315
pubmed: 34089739
Crit Care Explor. 2022 Feb 21;4(2):e0646
pubmed: 35211685
Ann Am Thorac Soc. 2017 Dec;14(12):1818-1826
pubmed: 28910146
Int J Qual Health Care. 2007 Dec;19(6):349-57
pubmed: 17872937
Chest. 2023 Mar;163(3):533-542
pubmed: 36343687
Crit Care Explor. 2022 Feb 18;10(2):e0638
pubmed: 35211681
Intensive Care Med. 2018 Jan;44(1):22-37
pubmed: 29218379
Am J Prev Med. 2016 Oct;51(4 Suppl 2):S124-31
pubmed: 27371105
Implement Sci. 2020 Jul 20;15(1):56
pubmed: 32690104
Crit Care. 2021 Apr 6;25(1):128
pubmed: 33823862
Crit Care Med. 2021 Mar 1;49(3):490-502
pubmed: 33405409
Ann Am Thorac Soc. 2023 Jan;20(1):83-93
pubmed: 35947776
Lancet Respir Med. 2021 Sep;9(9):989-998
pubmed: 34224674
Crit Care Explor. 2021 Mar 12;3(3):e0361
pubmed: 33786437

Auteurs

Chad H Hochberg (CH)

Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University, Baltimore, MD.

Mary E Card (ME)

Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University, Baltimore, MD.

Bhavna Seth (B)

Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University, Baltimore, MD.

David N Hager (DN)

Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University, Baltimore, MD.

Michelle N Eakin (MN)

Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University, Baltimore, MD.

Classifications MeSH