Repeat expansions in

NOP56 SCA36 repeat expansion spinocerebellar ataxia whole-genome sequencing

Journal

Brain communications
ISSN: 2632-1297
Titre abrégé: Brain Commun
Pays: England
ID NLM: 101755125

Informations de publication

Date de publication:
2023
Historique:
received: 16 01 2023
revised: 11 07 2023
accepted: 12 09 2023
medline: 9 10 2023
pubmed: 9 10 2023
entrez: 9 10 2023
Statut: epublish

Résumé

Spinocerebellar ataxias form a clinically and genetically heterogeneous group of neurodegenerative disorders characterized by progressive cerebellar ataxia. Their prevalence varies among populations and ethnicities. Spinocerebellar ataxia 36 is caused by a GGCCTG repeat expansion in the first intron of the

Identifiants

pubmed: 37810464
doi: 10.1093/braincomms/fcad244
pii: fcad244
pmc: PMC10558097
doi:

Types de publication

Journal Article

Langues

eng

Pagination

fcad244

Subventions

Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/S006753/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/S01165X/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/T001712/1
Pays : United Kingdom

Investigateurs

J C Ambrose (JC)
P Arumugam (P)
R Bevers (R)
M Bleda (M)
F Boardman-Pretty (F)
C R Boustred (CR)
H Brittain (H)
M A Brown (MA)
M J Caulfield (MJ)
G C Chan (GC)
A Giess (A)
J N Griffin (JN)
A Hamblin (A)
S Henderson (S)
T J P Hubbard (TJP)
R Jackson (R)
L J Jones (LJ)
D Kasperaviciute (D)
M Kayikci (M)
A Kousathanas (A)
L Lahnstein (L)
A Lakey (A)
S E A Leigh (SEA)
I U S Leong (IUS)
F J Lopez (FJ)
F Maleady-Crowe (F)
M McEntagart (M)
F Minneci (F)
J Mitchell (J)
L Moutsianas (L)
M Mueller (M)
N Murugaesu (N)
A C Need (AC)
P O'Donovan (P)
C A Odhams (CA)
C Patch (C)
D Perez-Gil (D)
M B Pereira (MB)
J Pullinger (J)
T Rahim (T)
A Rendon (A)
T Rogers (T)
K Savage (K)
K Sawant (K)
R H Scott (RH)
A Siddiq (A)
A Sieghart (A)
S C Smith (SC)
A Sosinsky (A)
A Stuckey (A)
M Tanguy (M)
A L Taylor Tavares (AL)
E R A Thomas (ERA)
S R Thompson (SR)
A Tucci (A)
M J Welland (MJ)
E Williams (E)
K Witkowska (K)
S M Wood (SM)
M Zarowiecki (M)

Informations de copyright

© The Author(s) 2023. Published by Oxford University Press on behalf of the Guarantors of Brain.

Déclaration de conflit d'intérêts

The authors report no competing interests.

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Auteurs

Tanya Lam (T)

Department of Clinical Genetics, Great Ormond Street Hospital NHS Trust, London, WC1N 3JH, UK.

Clarissa Rocca (C)

Clinical Pharmacology, William Harvey Research Institute, School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK.
Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, London, WC1N 3BG, UK.

Kristina Ibanez (K)

Clinical Pharmacology, William Harvey Research Institute, School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK.

Anupriya Dalmia (A)

Clinical Pharmacology, William Harvey Research Institute, School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK.

Samuel Tallman (S)

Genomics England, London, E14 5AB, UK.

Marios Hadjivassiliou (M)

Academic Department of Neurosciences and Neuroradiology, Sheffield Teaching Hospitals NHS Trust, Sheffield, S10 2JF, UK.

Anke Hensiek (A)

Department of Clinical Neurosciences, Addenbrookes Hospital, Cambridge, CB2 0QQ, UK.

Andrea Nemeth (A)

Oxford Centre for Genomic Medicine, Oxford University Hospitals National Health Service Foundation Trust, Oxford, OX3 9DU, UK.

Stefano Facchini (S)

Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, London, WC1N 3BG, UK.

Nicholas Wood (N)

Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, London, WC1N 3BG, UK.

Andrea Cortese (A)

Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, London, WC1N 3BG, UK.
Department of Brain and Behavioural Sciences, University of Pavia, Pavia, 27100, Italy.

Henry Houlden (H)

Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, London, WC1N 3BG, UK.

Arianna Tucci (A)

Clinical Pharmacology, William Harvey Research Institute, School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK.

Classifications MeSH